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Hypertrophic pyloric stenosis in twins: same genes or same environments?

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Abstract

The aetiology of infantile hypertrophic pyloric stenosis (IHPS) remains obscure. Cases in twins, usually monozygotic, have been sporadically reported as evidence for the genetic origin of the disease. We present a case of IHPS in a pair of dizygotic male twins together with a review of the literature, focusing on the question of whether the twin cases actually support a genetic or an acquired nature of IHPS.

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Authors and Affiliations

  1. Department of Paediatric Surgery, University of Crete, P.O. Box 2208, Heraklion, 71003, Greece

    K. Velaoras & G. Charissis

  2. Department of Paediatrics, University Hospital of Heraklion, P.O. Box 1352, 71500, Heraklion, Greece

    M. Bitsori

  3. Department of Paediatrics, University of Crete, P.O. Box 2208, Heraklion, 71003, Greece

    E. Galanakis

Authors
  1. K. Velaoras
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  2. M. Bitsori
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  3. E. Galanakis
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  4. G. Charissis
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Corresponding author

Correspondence to M. Bitsori.

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Velaoras, K., Bitsori, M., Galanakis, E. et al. Hypertrophic pyloric stenosis in twins: same genes or same environments?. Ped Surgery Int 21, 669–671 (2005). https://doi.org/10.1007/s00383-005-1435-4

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  • DOI: https://doi.org/10.1007/s00383-005-1435-4

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