Abstract
Two cases of recurrent pilocytic astrocytoma with leptomeningeal dissemination (LMD) are described. A 6-year-old boy presented with a cerebellar tumor, which was subtotally removed. Tumor recurrence with LMD occurred 4 years later. Reoperation for tumor removal followed by craniospinal irradiation stabilized the LMD over 5 years. A 4-year-old girl presented with a chiasmatic-hypothalamic tumor. Partial removal of the tumor was followed by radiation therapy. Tumor regrowth with LMD occurred 4 years later and was managed by reoperation, chemotherapy and radiotherapy. Tumor recurrence with LMD can be stabilized by multimodal treatment without tumor progression.
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Received: 20 June 1997 Revised: 10 November 1997
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Tamura, M., Zama, A., Kurihara, H. et al. Management of recurrent pilocytic astrocytoma with leptomeningeal dissemination in childhood. Child's Nerv Syst 14, 617–622 (1998). https://doi.org/10.1007/s003810050286
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DOI: https://doi.org/10.1007/s003810050286