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Germinoma in cerebral hemisphere associated with Down syndrome

Child's Nervous System volume 13, pages 563–566 (1997)Cite this article

Abstract

A Down syndrome patient with germinoma developing in the cerebral hemisphere is reported. A review of the literature yielded only 14 cases of Down syndrome with brain tumors, including our case. This finding of brain tumors in patients with Down syndrome may reflect chance occurrence. However, it is of interest in this regard that in 6 of the 14 (43%) reported cases the lesions were intracranial germ cell tumors.

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Affiliations

  1. Department of Neurosurgery, Gifu University School of Medicine, 40 Tsukasamachi, Gifu, 500 Japan Tel.: (81) 58-265-1241 Fax: (81) 58-265-9025, JP

    T. Nakashima, Yasuaki Nishimura, Noboru Sakai & Hiromu Yamada

  2. Department of Pathology, Gifu University School of Medicine, Gifu, 500 Japan, JP

    Akira Hara

Authors
  1. T. Nakashima
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  2. Yasuaki Nishimura
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  3. Noboru Sakai
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  4. Hiromu Yamada
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  5. Akira Hara
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Additional information

Received: 15 March 1996 Revised: 20 May 1996

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Cite this article

Nakashima, T., Nishimura, Y., Sakai, N. et al. Germinoma in cerebral hemisphere associated with Down syndrome. Child's Nerv Syst 13, 563–566 (1997). https://doi.org/10.1007/s003810050139

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  • DOI: https://doi.org/10.1007/s003810050139

  • Key words Down syndrome
  • Brain tumor
  • Germ cell tumor
  • Germinoma