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Family with recurrent cases of neural tube defects in Niamey (Niger)

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Summary

A series of patients affected by neural tube defects have been studied in Niamey (Niger). This population is highly consanguineous and we try estimating the number of cases in which a previous identical malformation has been reported in the family. We found only 4 families indicating that the percentage of such families is not increased in our population. However, we think that studying genetic factors in this specific population could allow to demonstrate susceptibility genes that can act on this pathology.

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References

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Authors and Affiliations

  1. Service de Neurochirurgie Hôpital National de Niamey (HNN), Niamey, Niger

    A. B. Kelani

  2. Faculté des Sciences de la Santé–Université, Abdou Moumouni (UAM) de Niamey, Niamey, Niger

    A. B. Kelani

  3. Sorbonne Université, Centre National de la Recherche Scientifique (CNRS) UMR7622, Institut National pour la Santé et la Recherche Médicale (INSERM) U1156, Institut de Biologie Paris Seine–Laboratoire de Biologie du Développement (IBPS-LBD), 9 Quai Saint-Bernard, 75005, Paris, France

    M. Catala

Authors
  1. A. B. Kelani
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  2. M. Catala
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Contributions

AK studied the population, AK and MC analyzed the population for genetic findings, and AK and MC wrote the main manuscript. AK and MC reviewed the manuscript.

Corresponding author

Correspondence to M. Catala.

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The authors declare no competing interests.

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Kelani, A.B., Catala, M. Family with recurrent cases of neural tube defects in Niamey (Niger). Childs Nerv Syst 40, 975–976 (2024). https://doi.org/10.1007/s00381-024-06334-7

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  • DOI: https://doi.org/10.1007/s00381-024-06334-7

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