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Effect of cervical and lumbosacral spina bifida cystica on volumes of intracranial structures in children

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Abstract

Purpose

Spina bifida is a major disorder that occurs when the membranes of the spinal cord and medulla fail to close during the embryonic period and affects the individual for the rest of life. Some physical, mental, and social difficulties can be observed in the lives of children with spina bifida after surgery. The aim of this study is to determine what kind of volumetric changes occur in the brain when spina bifida occurs in different regions of the cord.

Methods

The volume of intracranial structures of 14 children aged 1 to 9 years (7 cervical, 7 lumbosacral) with different levels of spina bifida compared with vol2Brain.

Results

Spina bifida occurring in the cervical region was found to cause a greater volumetric reduction in subcortical structures, cortex and gyrus than spina bifida occurring in the lumbosacral region.

Conclusion

We believe that our study will help clinicians involved in the management of this disorder.

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Data availability

Data is available upon reasonable request.

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Acknowledgements

We would like to thank Lecturer Mustafa Günay Özdemir for his contribution to improving the grammar and sentence structures of the paper in English.

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Authors and Affiliations

  1. Cappadocia Vocational School, Department of Medical Services and Techniques, Cappadocia University, Nevsehir, Turkey

    Hüseyin Yiğit

  2. Department of Anatomy, Faculty of Medicine, Erciyes University, Kayseri, Turkey

    Hatice Güler

  3. Department of Anatomy, Faculty of Medicine, Ordu University, Ordu, Turkey

    Halil Yılmaz

  4. Department of Pediatric Radiology, Faculty of Medicine, Erciyes University, Kayseri, Turkey

    Ümmügülsüm Özgül Gümü & Zehra Filiz Karaman

  5. Department of Child Health and Diseases, Faculty of Medicine, Erciyes University, Kayseri, Turkey

    Tamer Güneş

Authors
  1. Hüseyin Yiğit
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  2. Hatice Güler
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  3. Halil Yılmaz
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  4. Ümmügülsüm Özgül Gümü
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  5. Zehra Filiz Karaman
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  6. Tamer Güneş
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Contributions

Hüseyin Yiğit wrote the manuscript, created the graphics, and reviewed the literature. Hatice Güler contributed to the manuscript writing and literature review, created the project. Halil Yılmaz made the statistical analysis and contributed to the manuscript writing and literature review. Ümmügülsüm Özgül Gümüş, Zehra Filiz Karaman, and Tamer Güneş assisted in patient selection and ensured the acquisition of radiological images and contributed literature review.

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Correspondence to Hüseyin Yiğit.

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Yiğit, H., Güler, H., Yılmaz, H. et al. Effect of cervical and lumbosacral spina bifida cystica on volumes of intracranial structures in children. Childs Nerv Syst 40, 527–535 (2024). https://doi.org/10.1007/s00381-023-06153-2

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  • DOI: https://doi.org/10.1007/s00381-023-06153-2

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