Abstract
Kaposiform hemangioendothelioma is an extremely rare vascular tumor which shows aggressive local growth. We present a case of rapid growing vascular skull tumor with dura invasion in a pediatric patient with neurofibromatosis type 1. A 14-year-old male complained of headache and dizziness for 1 month after minor head trauma. Brain magnetic resonance imaging (MRI) revealed a 5-cm-sized tumor in the left frontotemporal bone with internal hemorrhage and cystic changes. The gross total resection of tumor was done. At the 7-month follow-up, brain MRI revealed a recurrent skull tumor with intracranial dura mass. He underwent second surgery, and the pathologic diagnosis was suggestive of Kaposiform hemangioendothelioma. For this vascular proliferative tumor, mTOR inhibitor was treated for 6 months, and there was the recurred nodular-enhancing mass along the sphenoid ridge. After additional 2 months of medication, the following MRI revealed a decreased nodular-enhancing mass.
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Seong-Chan Jung and Tae-Young Jung wrote the main manuscript text, Sung-Soon Kim prepared all figures, Hee-Jo Baek provided the clinical information, Tae-Kyu Lee, Young-Jin Kim, and Tae-Young Jung reviewed the previous published articles. All authors reviewed the manuscript.
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This study complies with the World Medical Association Declaration of Helsinki, and this retrospective study was approved by the Institutional Review Board of Chonnam National University Hwasun Hospital. Written informed consent was obtained from the patient’s parents for publication of this case report and any accompanying images.
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Jung, SC., Jung, TY., Lee, TK. et al. Kaposiform hemangioendothelioma of skull base with dura invasion in a pediatric patient: a case report. Childs Nerv Syst 39, 3289–3294 (2023). https://doi.org/10.1007/s00381-023-06025-9
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DOI: https://doi.org/10.1007/s00381-023-06025-9