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Communicating hydrocephalus and raised intracranial pressure in association with multi-systemic smooth muscle dysfunction syndrome (MSMDS)

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Abstract

Multi-systemic smooth muscle dysfunction syndrome (MSMDS) is extremely rare and can manifest in multiple ways. Associated hydrocephalus has not yet been reported. Here, we report a three-year-old girl with communicating hydrocephalus and raised intracranial pressure secondary to MSMDS. Pathological mechanisms are proposed, as is the need to investigate patients diagnosed with MSMDS for ventriculomegaly and raised pressure.

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Authors and Affiliations

  1. Department of Neurosurgery, Alder Hey Children’s Charity NHS Foundation Trust, Liverpool, England, UK

    Anthony Roylance & Benedetta Pettorini

  2. Department of Neurology, Alder Hey Children’s Charity NHS Foundation Trust, Liverpool, England, UK

    Stefan Spinty

Authors
  1. Anthony Roylance
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  2. Stefan Spinty
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  3. Benedetta Pettorini
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Correspondence to Anthony Roylance.

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Roylance, A., Spinty, S. & Pettorini, B. Communicating hydrocephalus and raised intracranial pressure in association with multi-systemic smooth muscle dysfunction syndrome (MSMDS). Childs Nerv Syst 39, 825–828 (2023). https://doi.org/10.1007/s00381-022-05703-4

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  • DOI: https://doi.org/10.1007/s00381-022-05703-4

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