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Endoscopic biopsy of pineal tumors: two burr hole trans-foramen of Monro approach and endonasal trans-tuber cinereum approach

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Abstract

Introduction

The pineal region is a challenging area for neurosurgeons due to its innate anatomical features, such as its deep location, surrounding large draining veins, and adjacent critical neural structures.

Discussion

There is a high proportion of malignant tumors in the pineal gland, especially in children, and they are frequently accompanied by obstructive hydrocephalus. These cases require that surgical procedures can make a pathological diagnosis to guide further treatment strategies and immediately resolve increased intracranial pressure. Simultaneous endoscopic third ventriculostomy and biopsy have been regarded as the first-line surgical intervention before establishing a definite treatment plan. However, it is not always successful because various factors affect the surgical procedures, such as the location and extent of the tumor, degree of ventriculomegaly, location and size of the massa intermedia, and size of the foramen of Monro.

Conclusion

Here, we briefly reviewed the points to be considered in endoscopic biopsy of pineal tumors and introduced an alternative surgical procedure, the endoscopic endonasal trans-tuber cinereum approach, to surmount the anatomical hurdles.

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References

  1. Hirato J, Nakazato Y (2001) Pathology of pineal region tumors. J Neurooncol 54:239–249

    Article  CAS  PubMed  Google Scholar 

  2. Phi JH, Kim SK, Lee J, Park CK, Kim IH, Ahn HS, Shin HY, Kim IO, Jung HW, Kim DG, Paek SH, Wang KC (2013) The enigma of bifocal germ cell tumors in the suprasellar and pineal regions: synchronous lesions or metastasis? J Neurosurg Pediatr 11:107–114

    Article  PubMed  Google Scholar 

  3. Cho KT, Wang KC, Kim SK, Shin SH, Chi JG, Cho BK (2002) Pediatric brain tumors: statistics of SNUH, Korea (1959–2000). Childs Nerv Syst 18:30–37

    Article  PubMed  Google Scholar 

  4. Wong TT, Ho DM, Chang KP, Yen SH, Guo WY, Chang FC, Liang ML, Pan HC, Chung WY (2005) Primary pediatric brain tumors: statistics of Taipei VGH, Taiwan (1975–2004). Cancer 104:2156–2167

    Article  PubMed  Google Scholar 

  5. Ellenbogen RG, Moores LE (1997) Endoscopic management of a pineal and suprasellar germinoma with associated hydrocephalus: technical case report. Minim Invasive Neurosurg 40:13–16

    Article  CAS  PubMed  Google Scholar 

  6. Wong TT, Chen HH, Liang ML, Yen YS, Chang FC (2011) Neuroendoscopy in the management of pineal tumors. Childs Nerv Syst 27:949–959

    Article  PubMed  Google Scholar 

  7. Roth J, Constantini S (2015) Combined rigid and flexible endoscopy for tumors in the posterior third ventricle. J Neurosurg 122:1341–1346

    Article  PubMed  Google Scholar 

  8. Ahmed AI, Zaben MJ, Mathad NV, Sparrow OC (2015) Endoscopic biopsy and third ventriculostomy for the management of pineal region tumors. World Neurosurg 83:543–547

    Article  PubMed  Google Scholar 

  9. Morgenstern PF, Souweidane MM (2013) Pineal region tumors: simultaneous endoscopic third ventriculostomy and tumor biopsy. World Neurosurg 79:S18 (e19−13)

    Article  Google Scholar 

  10. Oi S, Shibata M, Tominaga J, Honda Y, Shinoda M, Takei F, Tsugane R, Matsuzawa K, Sato O (2000) Efficacy of neuroendoscopic procedures in minimally invasive preferential management of pineal region tumors: a prospective study. J Neurosurg 93:245–253

    Article  CAS  PubMed  Google Scholar 

  11. Wang KC, Cho BK, Kim CS, Kim SD (1998) Control of intraoperative bleeding with hydrostatic pressure during endoscopic surgery. Childs Nerv Syst 14:280–284

    Article  CAS  PubMed  Google Scholar 

  12. Pople IK, Athanasiou TC, Sandeman DR, Coakham HB (2001) The role of endoscopic biopsy and third ventriculostomy in the management of pineal region tumours. Br J Neurosurg 15:305–311

    Article  CAS  PubMed  Google Scholar 

  13. Attri G, Gosal JS, Khatri D, Das KK, Bhaisora KS, Mehrotra A, Sardhara J, Srivastava AK, Behari S, Jaiswal S, Jaiswal AK (2020) Endoscopic third ventriculostomy and simultaneous tumor biopsy in pineal region tumors using the “single burr hole” technique: an analysis of 34 cases. Asian J Neurosurg 15:976–982

    Article  PubMed  PubMed Central  Google Scholar 

  14. Takami H, Graffeo CS, Perry A, Giannini C, Nakazato Y, Saito N, Matsutani M, Nishikawa R, Ichimura K, Daniels DJ (2022) Roles of tumor markers in central nervous system germ cell tumors revisited with histopathology-proven cases in a large international cohort. Cancers (Basel) 14

  15. O’Brien DF, Hayhurst C, Pizer B, Mallucci CL (2006) Outcomes in patients undergoing single-trajectory endoscopic third ventriculostomy and endoscopic biopsy for midline tumors presenting with obstructive hydrocephalus. J Neurosurg 105:219–226

    PubMed  Google Scholar 

  16. Al-Saiari S, Asiri FA, Farag AA, Alghamdi F, Rezk E, Al Orabi K, Abdoh MG, Rasheedi JK, Moshref R (2022) Multiple lessons learned from a single case: complications from pineal germinoma management. Surg Neurol Int 13:29

    Article  PubMed  PubMed Central  Google Scholar 

  17. Rhoton AL Jr (2002) The lateral and third ventricles. Neurosurgery 51:S207-271

    Article  PubMed  Google Scholar 

  18. Chernov MF, Kamikawa S, Yamane F, Ishihara S, Kubo O, Hori T (2006) Neurofiberscopic biopsy of tumors of the pineal region and posterior third ventricle: indications, technique, complications, and results. Neurosurgery 59:267–277

    Article  PubMed  Google Scholar 

  19. Cavallo LM, Di Somma A, de Notaris M, Prats-Galino A, Aydin S, Catapano G, Solari D, de Divitiis O, Somma T, Cappabianca P (2015) Extended endoscopic endonasal approach to the third ventricle: multimodal anatomical study with surgical implications. World Neurosurg 84:267–278

    Article  PubMed  Google Scholar 

  20. Kassam AB, Prevedello DM, Thomas A, Gardner P, Mintz A, Snyderman C, Carrau R (2008) Endoscopic endonasal pituitary transposition for a transdorsum sellae approach to the interpeduncular cistern. Neurosurgery 62:57–72

    PubMed  Google Scholar 

  21. Kim YH, Kang H, Dho YS, Hwang K, Joo JD, Kim YH (2021) Multi-layer Onlay graft using hydroxyapatite cement placement without cerebrospinal fluid diversion for endoscopic skull base reconstruction. J Korean Neurosurg Soc 64:619–630

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Kim KH, Kim YH, Dho YS, Kim JH, Hong SD, Choi JW, Seol HJ, Nam DH, Lee JI, Park CK, Kong DS (2018) Is low-lying optic chiasm an obstacle to an endoscopic endonasal approach for retrochiasmatic craniopharyngiomas? (Korean Society of Endoscopic Neurosurgery -003). World Neurosurg 114:e306–e316

    Article  PubMed  Google Scholar 

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Authors and Affiliations

Authors

Contributions

Yong Hwy Kim: writing manuscript, preparing the figures, organizing the paragraph, reviewing the manuscript, and electric submission. Ji Hoon Phi: writing manuscript, preparing the figures, organizing the paragraph, reviewing the manuscript. Seung-Ki Kim: concept and review of the manuscript. Kyu-Chang Wang: concept and review of the manuscript.

Corresponding authors

Correspondence to Seung-Ki Kim or Kyu-Chang Wang.

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The study was approved by the Institutional Review Board of Seoul National University Hospital (No. 2205–088-1324) and was conducted according to the Declaration of Helsinki. The requirement for informed consent was waived owing to the retrospective nature of the study.

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Kim, Y.H., Phi, J.H., Kim, SK. et al. Endoscopic biopsy of pineal tumors: two burr hole trans-foramen of Monro approach and endonasal trans-tuber cinereum approach. Childs Nerv Syst 39, 2367–2375 (2023). https://doi.org/10.1007/s00381-022-05654-w

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