Skip to main content

Advertisement

Log in

Massive congenital immature teratoma of the lateral ventricle in a 33-day infant comorbidity with atrial septal defect

  • Case Report
  • Published:
Child's Nervous System Aims and scope Submit manuscript

Abstract

Congenital teratomas are extremely rare and mainly midline tumors arising in the pineal regions in childhood brain tumors which are rarer cases occur in the lateral ventricle. Atrial septal defect (ASD) is detected in approximately 0.15% of newborns. We report an intracranial massive immature teratoma of the lateral ventricle in a 33-day-old infant on account of its rare location, comorbidity, and rapidly increasing size after surgery. Based on our information, this was the first case of congenital immature teratoma of the lateral ventricle comorbidity with ASD.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Isaacs H Jr (1985) Perinatal (congenital and neonatal) neoplasms: a report of 110 cases. Pediatr Pathol 3:165–216

    Article  Google Scholar 

  2. Balestrini MR, Micheli R, Giordano L, Lasio G, Giombini S (1994) Brain tumors with symptomatic onset in the first two years of life. Child’s Nervous Syst: ChNS 10:104–110

    Article  CAS  Google Scholar 

  3. Jooma R, Kendall BE (1982) Intracranial tumours in the first year of life. Neuroradiology 23:267–274

    Article  CAS  Google Scholar 

  4. Vick GW 3rd, Bezold LI (2018) Isolated atrial septal defects (ASDs) in children: Classification, clinical features, and diagnosis. In: UpToDate, Post TW (Ed), UpToDate, Waltham, MA

  5. Sawamura Y, Ikeda J, Shirato H, Tada M, Abe H (1998) Germ cell tumours of the central nervous system: treatment consideration based on 111 cases and their long-term clinical outcomes. Eur J Cancer (Oxford, England : 1990) 34:104–110

    Article  CAS  Google Scholar 

  6. Jelinek J, Smirniotopoulos JG, Parisi JE, Kanzer M (1990) Lateral ventricular neoplasms of the brain: differential diagnosis based on clinical, CT, and MR findings. AJNR Am J Neuroradiol 11:567–574

    CAS  PubMed  PubMed Central  Google Scholar 

  7. Heifetz SA, Cushing B, Giller R, Shuster JJ, Stolar CJ, Vinocur CD, Hawkins EP (1998) Immature teratomas in children: pathologic considerations: a report from the combined Pediatric Oncology Group/Children’s Cancer Group. Am J Surg Pathol 22:1115–1124

    Article  CAS  Google Scholar 

  8. Fraumeni JF Jr (1960) Miller RW (1969) Cancer deaths in the newborn. Am J Dis Children 117:186–189

    Google Scholar 

  9. Odell JM, Allen JK, Badura RJ, Weinberger E (1987) Massive congenital intracranial teratoma: a report of two cases. Pediatr Pathol 7:333–340

    CAS  PubMed  Google Scholar 

  10. Pećina-Slaus N, Niku Eva-Martić T, Beros V, Tomas D (2007) Genetic alterations of E-cadherin and beta-catenin in germinoma and teratoma: report of two central nervous system cases. Pathol Oncol Res 13:370–374

    Article  Google Scholar 

  11. Radice GL (2013) N-cadherin-mediated adhesion and signaling from development to disease: lessons from mice. Prog Mol Biol Transl Sci 116:263–289

    Article  CAS  Google Scholar 

  12. Li J, Lan Z, Xu J (2014) Mystery case: giant mature teratoma of the lateral ventricle in a child. Neurology 83:e60–e61

    Article  Google Scholar 

  13. Lai PH, Hsu SS, Lo YS, Ho JT (2006) Mature teratoma of the lateral ventricle in adulthood: preoperative CT and MRI diagnosis. Neurology 66:E25–E26

    Article  Google Scholar 

  14. Selçuki M, Attar A, Yüceer N, Tuna H, Cakiroğlu E (1998) Mature teratoma of the lateral ventricle: report of two cases. Acta Neurochir 140:171–174

    Article  Google Scholar 

  15. Arslan E, Usul H, Baykal S, Acar E, Eyuboglu EE, Reis A (2007) Massive congenital intracranial immature teratoma of the lateral ventricle with retro-orbital extension: a case report and review of the literature. Pediatr Neurosurg 43:338–342

    Article  Google Scholar 

  16. Sinha VD, Dharker SR, Pandey CL (2001) Congenital intracranial teratoma of the lateral ventricle. Neurol India 49:170–173

    CAS  PubMed  Google Scholar 

  17. Chidambaram B, Yasha TC, Balasubramaniam V (2001) Massive triventricular teratoma in an infant. Child’s Nervous Syst 17:618–622

    Article  CAS  Google Scholar 

  18. Jain A, Dixit S, Datar S, Jain PK (2010) Large choroid plexus teratoma: a rare cause of congenital hydrocephalus. Indian J Pediatr 77:452–453

    Article  Google Scholar 

  19. Erman T, Göçer IA, Erdoğan S, Güneş Y, Tuna M, Zorludemir S (2005) Congenital intracranial immature teratoma of the lateral ventricle: a case report and review of the literature. Neurol Res 27:53–56

    Article  Google Scholar 

  20. Chien Y, Tsao P, Lee W, Peng S, Yau KJP (2000) Congenit Intracran Teratoma 22:72–74

    CAS  Google Scholar 

  21. Soares FA, Fischer SE, Reis MA, Soares EG (1996) Massive intracranial immature teratoma. Report of a case with polyhidramnios and intense pelvic pain. Arq Neuropsiquiatr 54:309–312

    Article  CAS  Google Scholar 

  22. Mazumdar M, Bacik J, Tickoo SK, Dobrzynski D, Donadio A, Bajorin D, Motzer R, Reuter V, Bosl GJ (2003) Cluster analysis of p53 and Ki67 expression, apoptosis, alpha-fetoprotein, and human chorionic gonadotrophin indicates a favorable prognostic subgroup within the embryonal carcinoma germ cell tumor. J Clin Oncol 21:2679–2688

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Xiaoqiang Wang.

Ethics declarations

Conflict of interest

The authors report no conflict of interest.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chen, A., Wei, J., Wang, J. et al. Massive congenital immature teratoma of the lateral ventricle in a 33-day infant comorbidity with atrial septal defect. Childs Nerv Syst 38, 217–221 (2022). https://doi.org/10.1007/s00381-021-05168-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00381-021-05168-x

Keywords

Navigation