Skip to main content


Log in

An acquired cerebral arteriovenous malformation after brain abscess treatment: case report and a review of the literature

  • Case Report
  • Published:
Child's Nervous System Aims and scope Submit manuscript


A cerebral arteriovenous malformation (AVM) is a congenital and static disease. However, there are increasing reports of acquired AVMs. The pathophysiology of an acquired AVM has not been fully elucidated but the suggested pathophysiology is a combination of genetic abnormalities and inflammatory cytokines caused by previous brain insults. We report a patient who developed an acquired AVM after the treatment for a brain abscess. She underwent Gamma Knife surgery to treat the acquired AVM. It is necessary to understand the characteristics of acquired AVMs and to further research acquired AVMs.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others


  1. Nagai Y, Anan M, Fujiki M (2020) Cerebral Arteriovenous malformations as acquired lesions: case reports and review of the literature. J Stroke Cerebrovasc Dis 29:105157

    Article  Google Scholar 

  2. Akimoto H, Komatsu K, Kubota Y (2003) Symptomatic de novo arteriovenous malformation appearing 17 years after the resection of two other arteriovenous malformations in childhood: case report. Neurosurgery 52:228–231 discussion 231-222

    PubMed  Google Scholar 

  3. Tasiou A, Tzerefos C, Alleyne CH Jr, Boccardi E, Karlsson B, Kitchen N, Spetzler RF, Tolias CM, Fountas KN (2020) Arteriovenous malformations: congenital or acquired lesions? World Neurosurg 134:e799–e807

    Article  Google Scholar 

  4. Dalton A, Dobson G, Prasad M, Mukerji N (2018) De novo intracerebral arteriovenous malformations and a review of the theories of their formation. Br J Neurosurg 32:305–311

    Article  CAS  Google Scholar 

  5. Shimoda Y, Osanai T, Nakayama N, Ushikoshi S, Hokari M, Shichinohe H, Abumiya T, Kazumata K, Houkin K (2016) De novo arteriovenous malformation in a patient with hereditary hemorrhagic telangiectasia. J Neurosurg Pediatr 17:330–335

    Article  Google Scholar 

  6. Lv X, Wang G (2018) Review of de novo cerebral arteriovenous malformation: haemorrhage risk, treatment approaches and outcomes. Neuroradiol J 31:224–229

    Article  Google Scholar 

  7. Leblanc GG, Golanov E, Awad IA, Young WL, Biology of Vascular Malformations of the Brain NWC (2009) Biology of vascular malformations of the brain. Stroke 40:e694–e702

    Google Scholar 

  8. Park SO, Wankhede M, Lee YJ, Choi EJ, Fliess N, Choe SW, Oh SH, Walter G, Raizada MK, Sorg BS, Oh SP (2009) Real-time imaging of de novo arteriovenous malformation in a mouse model of hereditary hemorrhagic telangiectasia. J Clin Invest 119:3487–3496

    CAS  PubMed  PubMed Central  Google Scholar 

  9. Sweeney M, Foldes G (2018) It takes two: endothelial-perivascular cell cross-talk in vascular development and disease. Front Cardiovasc Med 5:154

    Article  CAS  Google Scholar 

  10. Dogan SN, Bagcilar O, Mammadov T, Kizilkilic O, Islak C, Kocer N (2019) De novo development of a cerebral Arteriovenous malformation: case report and review of the literature. World Neurosurg 126:257–260

    Article  Google Scholar 

  11. Kim H, Su H, Weinsheimer S, Pawlikowska L, Young WL (2011) Brain arteriovenous malformation pathogenesis: a response-to-injury paradigm. Acta Neurochir Suppl 111:83–92

    Article  Google Scholar 

  12. Yeo JJ, Low SY, Seow WT, Low DC (2015) Pediatric de novo cerebral AVM: report of two cases and review of literature. Childs Nerv Syst 31:609–614

    Article  Google Scholar 

  13. Kim H, Pawlikowska L, Chen Y, Su H, Yang GY, Young WL (2009) Brain arteriovenous malformation biology relevant to hemorrhage and implication for therapeutic development. Stroke 40:S95–S97

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations


Corresponding author

Correspondence to Seung-Ki Kim.

Ethics declarations

Conflict of interest

The authors have no conflicts of interests to report.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Park, H., Koh, E.J., Lee, E.J. et al. An acquired cerebral arteriovenous malformation after brain abscess treatment: case report and a review of the literature. Childs Nerv Syst 37, 2923–2926 (2021).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: