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Leiomyosarcoma in a cervical myelomeningocele: a rare complication in a neglected case

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Abstract

Background and importance

Asymptomatic myelomeningoceles are usually more of cosmetic deformities and left without evaluation and untreated, amongst low socio-economic strata. Such midline swellings, if left neglected may become the seat for malignancies, usually of squamous cell origin.

Clinical presentation

The authors report a case of an 18-year-old male patient who developed leiomyosarcoma within chronically neglected cervical myelomeningocele.

Conclusion

A non-healing ulcer of any aetiology is a bed for carcinogenesis. Neglected myelomeningoceles, for any reason, may convert a benign entity to a malignant pathology. To our best knowledge, this is the first case of a leiomyosarcoma arising de novo from myelomeningocele.

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Authors and Affiliations

  1. Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India

    Sandeep Mohindra, Aman Batish & Manjul Tripathi

  2. Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

    Kaniyappan Nambiyar & Kirti Gupta

Authors
  1. Sandeep Mohindra
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  2. Aman Batish
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  3. Manjul Tripathi
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  4. Kaniyappan Nambiyar
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  5. Kirti Gupta
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Corresponding author

Correspondence to Sandeep Mohindra.

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Conflict of interest

The authors do not have any personal or institutional financial interest in drugs, materials or devices described in the present submission.

IRB/ethics committee approval

No approval was required as the standard operating/management procedures were adopted. The authors report a developmental anomaly in a patient and its management protocol described in this report is a standardized procedure.

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Detailed patient consent is available with the authors. Available consent includes radiology scans and clinical pictures for academic publication purposes.

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Mohindra, S., Batish, A., Tripathi, M. et al. Leiomyosarcoma in a cervical myelomeningocele: a rare complication in a neglected case. Childs Nerv Syst 37, 2097–2103 (2021). https://doi.org/10.1007/s00381-020-04928-5

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  • DOI: https://doi.org/10.1007/s00381-020-04928-5

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