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Infantile intraorbital Ewing’s sarcoma: case report and review of the literature

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Abstract

We reported a 7-month-old female with intraorbital Ewing’s sarcoma. Infantile Ewing’s sarcoma is rare and its prognosis is poor. Ewing’s sarcoma of orbital origin is even rare. There has been only 1 case of infantile intraorbital Ewing’s sarcoma reported, and only 5 infantile primary orbital ESFTs (Ewing’s sarcoma family of tumors) have been reported. Among these 5 cases, 2 infants who did not receive multimodal therapy died, whereas 3 who received multimodal therapy demonstrated long-term survival. The present case was also treated with multimodal therapy consisting of surgery, chemotherapy, and proton beam radiotherapy. There is no recurrence at 15 months follow-up. No specific treatment strategies have been established yet, and accumulation of cases is necessary. Ewing’s sarcoma should be included in the differential diagnosis of infantile intraorbital tumors.

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Authors and Affiliations

  1. Division of Neurosurgery, National Center for Child Health and Development, Okura 2-10-1, Setagaya-ku, Tokyo, 157-8535, Japan

    Eitaro Ishisaka, Kenichi Usami & Hideki Ogiwara

  2. Division of Neuro-Oncology, National Center for Child Health and Development, Tokyo, Japan

    Chikako Kiyotani & Keita Terashima

Authors
  1. Eitaro Ishisaka
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  2. Kenichi Usami
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  3. Chikako Kiyotani
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  4. Keita Terashima
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  5. Hideki Ogiwara
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Correspondence to Hideki Ogiwara.

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Ishisaka, E., Usami, K., Kiyotani, C. et al. Infantile intraorbital Ewing’s sarcoma: case report and review of the literature. Childs Nerv Syst 37, 299–304 (2021). https://doi.org/10.1007/s00381-020-04606-6

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  • DOI: https://doi.org/10.1007/s00381-020-04606-6

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