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A case of focal cortical dysplasia type Ib atypically showing reversible intensity changes on magnetic resonance imaging which could be affected by epileptic discharge activity

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Abstract

Focal cortical dysplasia (FCD) was first described as a distinct neuropathological entity in 1971 by Taylor and colleagues. FCD is thought to be an embryological migration disorder and is thus considered a non-progressive, unchangeable disease throughout life. A 9-year-old right-handed boy was referred from a local hospital for medically intractable epileptic seizures. Serial magnetic resonance images (MRI) showed intensity changes that indicated exacerbation and remission. After presurgical evaluations including intracranial video-electroencephalogram monitoring, we performed a lesionectomy aided by MRI and epileptic focus resection. He has been free from seizures for more than 3 years. Neuropathological findings showed FCD type Ib. We surgically treated a patient with FCD, which showed MRI intensity changes indicating exacerbation and remission. Although FCD type Ib is generally invisible on MRI, in this patient, changes in intensity on MRI made FCD type Ib visible.

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Authors and Affiliations

  1. Department of Neurosurgery, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Hamamatsu, Shizuoka, 430-8558, Japan

    Naoto Kuroda

  2. Comprehensive Epilepsy Center, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Nakaku, Hamamatsu, Shizuoka, 430-8558, Japan

    Ayataka Fujimoto, Hideo Enoki & Tohru Okanishi

  3. Department of Pathology, Seirei Hamamatsu General Hospital, 2-12-12 Sumiyoshi, Hamamatsu, Shizuoka, 430-8558, Japan

    Yoshifumi Arai

Authors
  1. Naoto Kuroda
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  2. Ayataka Fujimoto
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  3. Hideo Enoki
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  4. Yoshifumi Arai
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  5. Tohru Okanishi
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Corresponding author

Correspondence to Ayataka Fujimoto.

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Written informed consent for publication of case details was obtained from the patient’s parents. This study was approved by the ethics committee at the Seirei Hamamatsu General Hospital.

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The authors declare that they have no conflict of interest.

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Kuroda, N., Fujimoto, A., Enoki, H. et al. A case of focal cortical dysplasia type Ib atypically showing reversible intensity changes on magnetic resonance imaging which could be affected by epileptic discharge activity. Childs Nerv Syst 35, 883–887 (2019). https://doi.org/10.1007/s00381-019-04093-4

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  • DOI: https://doi.org/10.1007/s00381-019-04093-4

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