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A rare clinical presentation: a pleomorphic xanthoastrocytoma presenting with intracerebral haemorrhage and metastasizing vigorously—case report and review of the literature

Child's Nervous System volume 35, pages 355–362 (2019)Cite this article

Abstract

Metastasis of an intracranial tumour is not a common situation in our daily neurosurgical practice. Pleomorphic xanthoastrocytoma is also a rare glial tumour with relatively a favourable prognosis among other CNS pathologies. Here, we present an anaplastic pleomorphic xanthoastrocytoma case which shows both haematogenous and lymphatic metastasis which is described first time in the up-to-date literature. Our case is a 17-year-old male operated for a right occipital intra-axial lesion with a diagnosis of anaplastic pleomorphic xanthoastrocytoma which recurs 5 years later and metastasize vigorously through haematogenous and lymphatic routes. A rare-presenting symptom for this pathology is also intracerebral haemorrhage. This is the ninth case report in the literature which presents initially with this entity.

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Acknowledgments

The authors thank Mrs. Özlem Yapıcıer, MD for her contribution for editing figures and details related to pathological headings.

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  1. Division of Pediatric Neurosurgery, Acıbadem University School of Medicine, Altunizade Mah. Yurtcan Sk. NO:1, 34662, Üsküdar/İstanbul, Turkey

    Gülden Demirci Otluoğlu & M. Memet Özek

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  1. Gülden Demirci Otluoğlu
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  2. M. Memet Özek
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Correspondence to Gülden Demirci Otluoğlu.

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Demirci Otluoğlu, G., Özek, M.M. A rare clinical presentation: a pleomorphic xanthoastrocytoma presenting with intracerebral haemorrhage and metastasizing vigorously—case report and review of the literature. Childs Nerv Syst 35, 355–362 (2019). https://doi.org/10.1007/s00381-018-3960-1

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  • DOI: https://doi.org/10.1007/s00381-018-3960-1

Keywords

  • Pleomorphic xanthoastrocytoma
  • Haemorrhage
  • Anaplastic PXA
  • Lesion