Guillain-Barré syndrome in children: subtypes and outcome

  • Zeynep Selen Karalok
  • Birce Dilge Taskin
  • Zeliha Brohi Yanginlar
  • Esra Gurkas
  • Alev Guven
  • Aydan Degerliyurt
  • Ece Unlu
  • Gulsen Kose
Original Paper



This study reviews the clinical features, subtypes, and outcomes of childhood Guillain-Barré syndrome (GBS).


Fifty-four children who attended a tertiary care training and research hospital in Turkey were enrolled in the study.


The mean age was 6.5 ± 4.2 years and 32 patients (59.5%) were male. The most common subtype of GBS was acute inflammatory demyelinating polyneuropathy (AIDP), which was seen in 27 patients (50%). Having antecedent history, especially upper respiratory tract infection was significantly more common in AIDP (P = 0.028). Sensorial symptoms were significantly more frequent in axonal type GBS (P = 0.001). When we compare the demyelinating and axonal forms, all of the groups had favorable outcome.


The diagnosis of pediatric GBS can be delayed because of its variable presentation. Early admission to hospital and early treatment are important for decreasing the need for respiratory support and improving the outcome.


Childhood GBS Early treatment Outcome Subtypes 


Compliance with ethical standards

Conflicts of interest

There are no conflicts of interest.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Zeynep Selen Karalok
    • 1
  • Birce Dilge Taskin
    • 1
  • Zeliha Brohi Yanginlar
    • 1
  • Esra Gurkas
    • 1
  • Alev Guven
    • 1
  • Aydan Degerliyurt
    • 1
  • Ece Unlu
    • 2
  • Gulsen Kose
    • 3
  1. 1.Department of Pediatric NeurologyAnkara Children’s Hematology-Oncology Training and Research HospitalDıskapı/AnkaraTurkey
  2. 2.Department of Physical Medicine and RehabilitationMinistry of Health Diskapi Yildirim Beyazit Education and Research HospitalAnkaraTurkey
  3. 3.Department of Pediatric NeurologySisli Hamidiye Etfal Research and Training HospitalIstanbulTurkey

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