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Currarino syndrome: report of five consecutive patients

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Abstract

Introduction

The Currarino syndrome is regarded as a developmental disorder based on its recognized etiological heterogeneity. This syndrome is thought to result from abnormal separation of the neuroectoderm from the endoderm. Our aim was to report the neurosurgical management of Currarino syndrome in children and adults and to describe what clinician could do if the Currarino triad was suspected.

Case reports

We present five cases of Currarino triad who underwent surgical intervention. All patients had sacral bony deformity, anorectal malformations, and anterior sacral meningocele. A 40-year-old-male had chronic constipation. He was incidentally diagnosed with Currarino syndrome. A 19-year-old-female suffered from a slight weakness in lower extremities and urinary incontinence. Her past medical history was remarkable for anal atresia. The other three cases were children.

Conclusion

When an anterior sacral meningocele is encountered, Currarino syndrome should be taken into consideration. Although it is rarity, the Currarino syndrome might be one of the causes of chronic constipation. Endoscopic or endoscope-assisted surgery via a posterior sacral route can be feasible for treatment of some of the patients with anterior sacral meningocele. Anterior meningocele pouch associated with Currarino syndrome will regresses over time following transdural ligation of its neck.

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Authors and Affiliations

  1. Department of Neurosurgery, Düzce University School of Medicine, Düzce, 81320, Turkey

    Soner Duru & Erhan Turkoglu

  2. Department of Neurosurgery, Selçuk University School of Medicine, Konya, Turkey

    Hakan Karabagli

  3. Department of Neurosurgery, Ege University School of Medicine, Izmir, Turkey

    Yusuf Erşahin

Authors
  1. Soner Duru
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  2. Hakan Karabagli
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  3. Erhan Turkoglu
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  4. Yusuf Erşahin
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Correspondence to Soner Duru.

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Duru, S., Karabagli, H., Turkoglu, E. et al. Currarino syndrome: report of five consecutive patients. Childs Nerv Syst 30, 547–552 (2014). https://doi.org/10.1007/s00381-013-2274-6

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  • DOI: https://doi.org/10.1007/s00381-013-2274-6

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