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Intramedullary spinal cord cavernous malformations presenting with unexplained chest pain: case report and review of the literature

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Abstract

Introduction

Intramedullary spinal cord cavernous malformations are very uncommon in pediatric age, with only 26 cases reported within the available literature to date. The diagnosis of such lesions is often difficult and delayed because of their rarity and bizarre clinical presentation.

Case report

We report a case of intramedullary spinal cord cavernous malformation in a girl, in which sudden onset chest pain was the only presenting symptom, followed by appearance of neurological deficits after 5 days. We review the available literature discussing clinical features and principles of management of these lesions in children.

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References

  1. Khalatbari MR, Hamidi M, Moharamzad Y (2011) Pediatric intramedullary cavernous malformation of the conus medullaris: case report and review of the literature. Childs Nerv Syst 27(3):507–511

    Article  PubMed  Google Scholar 

  2. Kharkar S, Shuck J, Conway J, Rigamonti D (2007) The natural history of conservatively managed symptomatic intramedullary spinal cord cavernomas. Neurosurgery 60:865–872

    Article  PubMed  Google Scholar 

  3. Sandalcioglu IE, Wiedemayer H, Gasser T, Asgari S, Engelhorn T, Stolke D (2003) Intramedullary spinal cord cavernous malformation: clinical features and risk of hemorrhage. Neurosurg Rev 26:253–256

    Article  PubMed  Google Scholar 

  4. Bakir A, Savas A, Yilmaz E, Savaş B, Erden E, Cağlar S, Sener O (2006) Spinal intradural-intramedullary cavernous malformation: case report and literature review. Pediatr Neurosurg 42:35–37

    Article  PubMed  Google Scholar 

  5. Narayan P, Barrow DL (2003) Intramedullary spinal cavernous malformation following spinal irradiation. Case report and review of the literature. J Neurosurg 98:68–72

    PubMed  Google Scholar 

  6. Anson JA, Spetzler RF (1993) Surgical resection of intramedullary spinal cord cavernous malformations. J Neurosurg 78:446–451

    Article  PubMed  CAS  Google Scholar 

  7. Varoglu AO, Tan H, Onbas O, Tuzun Y, Deniz O, Gursan N (2008) Intramedullary angioma with bilateral arm hypothermia. Br J Neurosurg 22:687–689

    Article  PubMed  CAS  Google Scholar 

  8. Marseglia GL, Savasta S, Ravelli A, Gaino TM, Burgio GR (1995) Recurrent chest pain as the presenting manifestation of spinal meningioma. Acta Paediatr 84:1086–1088

    Article  PubMed  CAS  Google Scholar 

  9. Selbst SM (2010) Approach to the child with chest pain. Pediatr Clin N Am 57(6):1221–1234

    Article  Google Scholar 

  10. Hussain MZ, Ishrat S, Salehuddin M, Mahmood M, Islam MT (2011) Chest pain in children: an update. Mymensingh Med J 20(1):165–167

    PubMed  CAS  Google Scholar 

  11. Noudel R, Litrè F, Vinchon M, Patey M, Rousseaux P (2008) Intramedullary spinal cord cavernous angioma in children: case report and literature review. Childs Nerv Syst 24(2):259–263

    Article  PubMed  Google Scholar 

  12. Cornips E, Vinken P, Ter Laak-Poort M, Beuls EA, Weber J, Vles JS (2010) Intramedullary cavernoma presenting with hematomyelia: report of two girls. Childs Nerv Syst 26:391–398

    Article  PubMed  Google Scholar 

  13. Nagib MG, O’Fallon MT (2002) Intramedullary cavernous angiomas of the spinal cord in the pediatric age group: a pediatric series. Pediatr Neurosurg 36:57–63

    Article  PubMed  Google Scholar 

  14. Ogilvy CS, Louis DN, Ojemann RG (1992) Intramedullary cavernous angiomas of the spinal cord: clinical presentation, pathological features, and surgical management. Neurosurgery 31:219–229

    Article  PubMed  CAS  Google Scholar 

  15. Gross BA, Du R, Popp AJ, Day AL (2010) Intramedullary spinal cord cavernous malformations. Neurosurg Focus 29(3):E14

    Article  PubMed  Google Scholar 

  16. Chen C-C, Wang C-M, Chu N-K, Wu KP-H, Tang SF-T, Wong AM-K (2008) Spinal cord arteriovenous malformation presenting as chest pain in a child. Spinal Cord 46:456–458

    Article  PubMed  Google Scholar 

  17. Jallo GI, Freed D, Zareck M, Epstein F, Kothbauer KF (2006) Clinical presentation and optimal management for intramedullary cavernous malformation. Neurosurg Focus 21:E10

    Article  PubMed  Google Scholar 

  18. Scott RM, Barnes P, Kupsky W, Adelman LS (1992) Cavernous angiomas of the central nervous system in children. J Neurosurg 76:38–46

    Article  PubMed  CAS  Google Scholar 

  19. Kolias AG, Debasish P, Aditya S, Azzam I, Atul T (2009) Paediatric intramedullary spinal cord cavernous malformation: case report and review of the literature. Clin Neurol Neurosurg 111:784–788

    Article  PubMed  Google Scholar 

  20. McGirt MJ, Chaichana KL, Atiba A, Bydon A, Witham TF, Yao KC, Jallo GI (2008) Incidence of spinal deformity after resection of intramedullary spinal cord tumors in children who underwent laminectomy compared with laminoplasty. J Neurosurg Pediatr 1(1):57–62

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Deparment of Pediatrics, Fondazione IRCCS Policlinico San Matteo, P.le Golgi 2, 27100, Pavia, Italy

    Salvatore Savasta, Mattia Algeri, Elisabetta De Sando & Gian Luigi Marseglia

  2. Department of Radiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

    Georgia Mussati

  3. Department of Neurosurgery, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

    Davide Locatelli

  4. Clinical Neurophysiology Service, C. Mondino National Institute of Neurology Foundation IRCCS, Pavia, Italy

    Alessandro Lozza

Authors
  1. Salvatore Savasta
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  2. Mattia Algeri
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  3. Elisabetta De Sando
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  4. Alessandro Lozza
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  5. Georgia Mussati
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  6. Davide Locatelli
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  7. Gian Luigi Marseglia
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Corresponding author

Correspondence to Salvatore Savasta.

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Savasta, S., Algeri, M., De Sando, E. et al. Intramedullary spinal cord cavernous malformations presenting with unexplained chest pain: case report and review of the literature. Childs Nerv Syst 29, 323–328 (2013). https://doi.org/10.1007/s00381-012-1941-3

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  • DOI: https://doi.org/10.1007/s00381-012-1941-3

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