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Benign epilepsy of childhood with centro-temporal spikes (BECTS) versus migraine: a neuropsychological assessment

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Abstract

Purpose

Epilepsy and migraine frequently show a clinical overlap. An increase in number of electroencephalographic abnormalities, such as centro-temporal spikes (CTS), may be observed in patients suffering from migraine, epileptic abnormalities that are typically in benign epilepsy of childhood with CTS (BECTS). The aim of this study is to better define the role of CTS in children with migraine compared to children with BECTS, in relation with their neuropsychological profile.

Methods

Thirty-two children were enrolled and divided into three groups on the basis of their diagnosis: 16 children (eight males and eight females, aged 12.3 ± 2.58 years) affected by BECTS, 8 patients (four males and four females, aged 11.8 ± 3.47 years) affected by BECTS and migraine, and 8 children (four males and four females, aged 13.5 ± 1.79 years) affected by migraine showing CTS abnormalities. A cognitive and neuropsychological assessment was performed, using Wechsler Intelligence Scale for Children—third edition and NEPSY II, in all patients.

Results and conclusions

A similar neuropsychological impairment was found in patients affected by BECTS and in those affected by BECTS and migraine; a significant deficit in short- and long-term verbal memory was evident in patients affected by migraine and CTS. CTS in patients with migraine can influence the neuropsychological tests, with a possible negative impact on language and learning development.

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Conflict of interest

None of the authors has any conflict of interest to disclose. We confirm that we have read the journal’s position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.

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Authors and Affiliations

  1. Child Neurology, NESMOS Dept., Faculty of Medicine and Psychology, Sapienza University, Via di Grottarossa, 1035-1039, Rome, 00189, Italy

    Pasquale Parisi & Claudia Martini

  2. Department of Pediatrics, University of Chieti, Chieti, Italy

    Sara Matricardi & Alberto Verrotti

  3. Child and Adolescent Neuropsychiatry Unit, University of L’Aquila, L’Aquila, Italy

    Elisabetta Tozzi & Enzo Sechi

Authors
  1. Pasquale Parisi
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  2. Sara Matricardi
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  3. Elisabetta Tozzi
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  4. Enzo Sechi
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  5. Claudia Martini
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  6. Alberto Verrotti
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Correspondence to Pasquale Parisi.

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Parisi, P., Matricardi, S., Tozzi, E. et al. Benign epilepsy of childhood with centro-temporal spikes (BECTS) versus migraine: a neuropsychological assessment. Childs Nerv Syst 28, 2129–2135 (2012). https://doi.org/10.1007/s00381-012-1867-9

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  • DOI: https://doi.org/10.1007/s00381-012-1867-9

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