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Computed tomography-guided stereotactic biopsy of intracranial lesions in pediatric patients

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Abstract

Purpose

The primary objective of this study was to report the results of author’s 18-year experience of diagnostic stereotactic biopsy procedures in children with intracranial lesions.

Methods and materials

A retrospective analysis was conducted on stereotactic procedures performed on children with brain tumor between 1989 and 2007.

Results

Stereotactic biopsy of intracranial tumors was performed in 172 children (69 girls, and 103 boys) with the mean age of 9.17 ± 3.66 years at the time of diagnosis. The most frequent anatomical location of lesions was brainstem (45.9%). Glioma was the most common diagnosis, represented in 90.7% of patients (156 patients). Other diagnosed tumors (4.7%) were classified as metastatic (1.7%), lymphomas (1.2%), oligodendroglioma (0.6%), craniopharyngioma (0.6%), and pineocytoma (0.6%). Nonneoplastic lesions were revealed in 4.7% of patients.

Conclusion

The most frequent brain pathology of children is glioma, but the incidence of brain lesions other than gliomas and the frequency of brain lesions in the inoperable areas are compelling reasons to establish tissue diagnosis.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Neuroscience Research Center, Tabriz University of Medical Sciences, Imam Reza Medical Center, Golgasht Street, Tabriz, Eastern Azerbaijan, Iran, 5166614756

    Ali Meshkini, Aimaz Afrough & Amir Hamdi

  2. Functional Neurosurgery and Stereotaxy Research Center, Shahid Beheshti University (Medical Sciences), Tehran, Iran

    Ali Meshkini, Sohrab Shahzadi, Alireza Zali & Khosro Parsa

Authors
  1. Ali Meshkini
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  2. Sohrab Shahzadi
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  3. Alireza Zali
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  4. Khosro Parsa
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  5. Aimaz Afrough
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Corresponding author

Correspondence to Amir Hamdi.

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Meshkini, A., Shahzadi, S., Zali, A. et al. Computed tomography-guided stereotactic biopsy of intracranial lesions in pediatric patients. Childs Nerv Syst 27, 2145–2148 (2011). https://doi.org/10.1007/s00381-011-1534-6

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  • DOI: https://doi.org/10.1007/s00381-011-1534-6

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