Abstract
Purpose
The purpose of this paper is to study the possible inheritance of nasal dermoid sinus cyst in the Finnish population.
Methods
A patient questionnaire and interview were utilized for this study.
Results
We identified nine patients with dermoid sinus cyst. Only one of them had familial nasal dermoid sinus cyst. We found no evidence for founder effect.
Conclusions
We report a pedigree with six affected individuals and an association of nasal dermoid sinus cyst and third ventricle colloid cyst. Whether patients or pedigrees with nasal dermoid sinus cyst (NDSC) and third ventricle colloid cysts represent a previously unrecognized syndrome or belong to the normal phenotypic spectrum of NDSC remains unclear. Our patient material suggests that only minority of NDSCs seem to be familial.
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Acknowledgments
T Klockars is doing research on the genetics of pediatric otorhinolaryngological diseases with financial support from the Wilhelm och Else Stockmanns Stiftelse.
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The authors have no financial or personal relationships that could influence this work.
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Saarinen, I., Karppinen, A., Saarinen, P. et al. Inheritance of nasal dermoid sinus cyst and evidence for association with third ventricle colloid cyst. Childs Nerv Syst 28, 117–120 (2012). https://doi.org/10.1007/s00381-011-1526-6
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DOI: https://doi.org/10.1007/s00381-011-1526-6