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Split medulla in association with multiple closed neural tube defects

  • Case Report
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Abstract

Purpose

We describe the case of a patient with a split medulla associated with multiple closed neural tube defects.

Case report

This 13-year-old female initially presented to our service at just over a year of age for neck abnormalities and a congenital midline occipital dermal sinus. MRI and CT scans showed the presence of multiple cervical vertebral segmentation abnormalities, a bony spur at the level of the craniocervical junction, split medulla, split cervical spinal cord, and a midline occipital dermal sinus. Since the patient’s neurological course had remained stable during follow-up for over 11 years, the only surgical procedure undertaken was excision of the dermal sinus to prevent infection.

Conclusions

The constellation of abnormalities indicates that the notochord was split early during gestation, both rostral and caudal to the cervicomedullary junction. Surgical intervention to treat the other malformations needs to be considered only if the patient develops a progressive neurological deficit.

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Acknowledgments

Ai Muroi, MD, received salary support from Rudi Shulte Research Institute, Santa Barbara, California.

The family provided written permission for the use of the photograph.

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Authors and Affiliations

  1. Division of Neurosurgery, Childrens Hospital Los Angeles, 1300 N. Vermont Avenue, Suite 1006, Los Angeles, CA, 90027, USA

    Ai Muroi, Karen L. Fleming & J. Gordon McComb

  2. Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

    Ai Muroi, Karen L. Fleming & J. Gordon McComb

Authors
  1. Ai Muroi
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  2. Karen L. Fleming
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  3. J. Gordon McComb
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Correspondence to Ai Muroi.

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Muroi, A., Fleming, K.L. & McComb, J.G. Split medulla in association with multiple closed neural tube defects. Childs Nerv Syst 26, 967–971 (2010). https://doi.org/10.1007/s00381-010-1098-x

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  • DOI: https://doi.org/10.1007/s00381-010-1098-x

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