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Morphometric analysis of the craniocervical juncture in children with Chiari I malformation and concomitant syringobulbia

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Abstract

Introduction

Although very uncommon, Chiari I malformation (CIM) with syringomyelia may be associated with concomitant syringobulbia. We hypothesized that the anatomy of the craniocervical region may be different in CIM patients with syringomyelia who develop syringobulbia in conjunction with their syringomyelia compared to other patients with CIM with and without syringomyelia. The present study was conducted in order to prove or disprove such a theory.

Materials and methods

A group of 189 children with operated CIM were reviewed for the presence of syringobulbia, and this cohort then underwent morphometric analyses of their craniocervical juncture. These measurements were then compared to both our prior patient findings and historic controls.

Results

The current study did not identify any morphometrical peculiarities for patients with CIM and syringobulbia compared to other CIM patients with and without isolated syringomyelia.

Conclusions

Based on our study, the mechanism behind such cerebrospinal fluid distention into the brain stem remains elusive with no single morphometrical difference in patients with CIM and syringobulbia compared to other patients with CIM. Perhaps, future testing aimed at identifying pressure gradients across the foramen magnum in patients with and without syringobulbia and concomitant CIM may be useful.

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Authors and Affiliations

  1. Pediatric Neurosurgery, Children’s Hospital, 1600 7th Avenue South ACC 400, Birmingham, AL, 35233, USA

    R. Shane Tubbs & W. Jerry Oakes

  2. University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA

    Matthew Bailey & William C. Barrow

  3. Department of Anatomical Sciences, St. George’s University, St. George’s, Grenada

    Marios Loukas

  4. Clarian Neuroscience Institute, Indianapolis Neurosurgical Group and Indiana University Department of Neurosurgery, Indianapolis, IN, USA

    Mohammadali M. Shoja

Authors
  1. R. Shane Tubbs
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  2. Matthew Bailey
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  3. William C. Barrow
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  4. Marios Loukas
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  5. Mohammadali M. Shoja
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  6. W. Jerry Oakes
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Corresponding author

Correspondence to R. Shane Tubbs.

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Tubbs, R.S., Bailey, M., Barrow, W.C. et al. Morphometric analysis of the craniocervical juncture in children with Chiari I malformation and concomitant syringobulbia. Childs Nerv Syst 25, 689–692 (2009). https://doi.org/10.1007/s00381-009-0810-1

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  • DOI: https://doi.org/10.1007/s00381-009-0810-1

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