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Germinoma of basal ganglia in female: case report and review of the literature

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Abstract

Introduction

Germinoma of basal ganglia in female is very rare. The authors present a case of germinoma located in the right temporal lobe and basal ganglia in female and raise a hypothesis for the sex disparity.

Materials and methods

A 13-year-old Chinese girl complained of weakness in the left extremities and intermittent headache for 2 years. Neuroimaging revealed an irregular lesion in the temple lobe and basal ganglia. A temporal polectomy was performed for the tumor.

Results and discussion

Histopathologic examination confirmed germinoma. The patient remains stable and tumor-free for 36 months after radiotherapy and chemotherapy. The authors’ hypothesis is that it is the individual hormone balance which leads to the male predominance of germinoma in the basal ganglia.

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Authors and Affiliations

  1. Beijing Neurosurgical Institute, Capital Medical University, Beijing, People’s Republic of China

    Shuyu Hao & Zhongcheng Wang

  2. Department of Neurosurgery, Beijing Tiantan Hospital, Beijing Neurosurgical Institute, Capital Medical University, Xili 6, Chongwen District, Beijing, 100050, People’s Republic of China

    Baiyun Liu, Jie Tang, Ge Jia, Yuqi Zhang & Zhenyu Ma

Authors
  1. Shuyu Hao
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  2. Baiyun Liu
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  3. Jie Tang
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  4. Ge Jia
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  5. Yuqi Zhang
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  6. Zhenyu Ma
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  7. Zhongcheng Wang
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Corresponding author

Correspondence to Baiyun Liu.

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Hao, S., Liu, B., Tang, J. et al. Germinoma of basal ganglia in female: case report and review of the literature. Childs Nerv Syst 25, 613–617 (2009). https://doi.org/10.1007/s00381-008-0769-3

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  • DOI: https://doi.org/10.1007/s00381-008-0769-3

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