Abstract
Case report
We report the case of a 16-year-old girl who developed hemangiopericytoma of the thoracic spine; the main clinical symptoms were of spastic paraparesis with sensory involvement and uro-fecal incontinence. She was initially put on antitubercular treatment keeping in mind the endemicity of tuberculosis in the region. When she deteriorated on conservative management, she was operated upon, and the histopathological report was suggestive of hemangiopericytoma.
Materials and methods
Additional immunocytochemistry was performed in the paraffin-embedded tumor sections.
Conclusions
An extremely rare case of primary epidural malignant hemangiopericytoma of the thoracic spinal column is described. It is a rare tumor, which is locally aggressive, and a potentially malignant tumor. The tumor is more commonly found in the cranium, and spinal involvement is rare, and only few case reports could be retrieved from the literature. We discuss the clinical profile, management, and outcome of spinal hemangiopericytomas along with pertinent review of the literature.
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References
Baglio CM, Crowson CN et al (1964) Hemangiopericytoma of Urachus: report of a case. J Urot 91:660–662
Bastin KT, Mehta MP (1992) Meningeal hemangiopericytoma: defining the role for radiation therapy. J Neurooncol 14:277–287
Blenkinsopp WK, Hobe JT (1966) Pedunculated hemangiopericytoma attached to the thoracic aorta. Thorax 21:193–196
Borg MF, Benjamin CS (1995) Haemangiopericytoma of the central nervous system. Australas Radiol 39:36–41
Brockunier A, Brun-Schwig A (1964) Pelvic hemangiopericytoma. Review of the literature and report of a case treated by posterior exenteration. Obstet Gynecol N Y 24:402–410
Brown DN (1962) Intracranial hemangiopericytoma—a clinical and pathologic study. (Thesis) Graduate School, University of Minnesota
Brunori A, Delitala A, Oddi G, Chiappetta F (1997) Recent experience in the management of meningeal hemangiopericytomas. Tumori 83:856–860
Ciappetta P, Celli P, Palma L, Mariottini A (1985) Intraspinal hemangiopericytomas. Report of two cases and review of the literature. Spine 10:27–31
Coffey RJ, Cascino TL, Shaw EG (1993). Radiosurgical treatment of recurrent hemangiopericytomas of the meninges: preliminary results. J Neurosurg 78:903–908
Das AK, Gans BJ (1965) Hemangiopericytoma of the oral cavity. Review of the literature and report of a case. J Oral Surg 23:456–460
Douglas JL, Mitchell R, Short DW (1966) Retroperitoneal hemangiopericytoma. Br J Surg 53:31–33
Enzinger FM, Smith BH (1976) Hemangiopericytoma. An analysis of 106 cases. Hum Pathol 7:61–82
Ernst CB, Adfll MR, Kahn DR (1965) Malignant hemangiopericytoma of the stomach. Surgery St Louis 58:351–356
Espat NJ, Lewis JJ, Leung D et al (2002) Conventional hemangiopericytoma: modern analysis of outcome. Cancer 95(8):1746–1751
Farrow GM, Harrison EG Jr, Utz DC, ReMine WH (1968) Sarcomas and sarcomatoid and mixed malignant tumors of the kidney in adults. Part 1. Cancer 22:545–550
Feldman F, Seaman WB (1964) Primary thoracic hemangiopericytoma. Radiology 82:998–1008
Fisher JH (1960) Hemangiopericytoma: a review of 20 cases. Can Med Ass J 83:1136–1139
Fuste FJ (1968) Primary hemangiopericytoma of the orbit. J Tenn Med Assoc 61:1003–1004
Galanis E, Buckner JC, Scheithauer BW, Kimmel DW, Schomberg PJ, Piepgras DG (1998) Management of recurrent meningeal hemangiopericytoma. Cancer 82:1915–1920
Goldberger RE, Schein CJ (1968) Hemangiopericytoma of the omentum: report of a case with a unique presentation and review of literature. Am Surg 34:291–295
Guthrie BL, Ebersold MJ, Scheithauer BW, Shaw EG (1989) Meningeal hemangiopericytomas: histopathological features, treatment and long-term follow-up of 44 cases. Neurosurgery 25:514–522
Hogle WP (2003) Malignant hemangiopericytoma: a clinical overview and case study. Clin J Oncol Nurs 7(1):57–62
Ijiri K, Yuasa S, Yone K et al (2002) Primary epidural hemangiopericytoma in the lumbar spine: a case report. Spine 27(7):E189–E192
Jaaskelainen J, Servo A, Haltia M, Wahlstrom T, Valtonen S (1985) Intracranial hemangio-pericytoma: radiology, surgery, radiotherapy and outcome in 21 patients. Surg Neurol 23:227–236
Jha N, McNeese M, Barkley H, Kong J (1987) Does radiotherapy have a role in hemangio-pericytoma management? Report on 14 new cases and a review of the literature. Int J Radiat Oncol Biol Phys 3:1399–1402
Lenczyk JM (1968) Nasal hemangiopericytoma. Arch Otolaryngol 87:536–539
Lieras H, Vauzflle JL, Guelpa G, Nerdhardt JH, Tairraz JP (1965) Hemangiopericytoma of cystic form of uterus. Diagnostic and therapeutic problems. Lyon Chir 61:863
Lin Y-J, Tu Y-K, Lin S-M, Shun C-T(1996) Primary hemangiopericytoma in the axis bone: case report and review of literature. Neurosurgery 39(2):397–400
MacCarty CS, Brown DN (1964) Orbital tumors in children. Clin Neurosurg 11:76–93
Someya M, Sakata KI, Oouchi A, Nagakura H, Satoh M, Hareyama M (2001) Four cases of meningeal hemangiopericytoma treated with surgery and radiotherapy. Jpn J Clin Oncol 31:548–552
McMaster MJ, Soule EH, Ivins JC (1975) Hemangiopericytoma. A clinicopathologic study and long-term follow-up of 60 patients. Cancer 36(6):2232–2244
Mira JG, Chu FC, Fortner JG (1977) The role of radiotherapy in the management of malignant hemangiopericytoma. Cancer 39:1254–1259
Mohammadianpanah M, Torabinejad S, Bagheri MH, Omidvari S, Mosalaei A, Ahmadloo N (2004) Primary epidural malignant hemangiopericytoma of thoracic spinal column causing cord compression: case report. Sao Paulo Med J 122(5):220–222
Nonaka M, Kohmura E, Hirata M, Hayakawa T (1998) Metastatic meningeal hemangiopericytoma of thoracic spine. Clin Neurol Neurosurg 100:228–230
Nunnery EW, Kahn LB, Reddick RL, Lipper S (1981) Hemangiopericytoma: a light microscopic and ultrastructural study. Cancer 47:906–914
O’beuen P, Brasfield RD (1965) Hemangiopericytoma. A follow up study. Cancer N Y 18:249–252
Palkovic S (1987) Multiple recurrence of an intracranial hemangiopericytoma. Neurosurg Rev 10:233–236
Payne BR, Prasad D, Steiner M, Steiner L (2000) Gamma surgery for hemangiopericytomas. Acta Neurochir 142:527–537
Perez CA, Chao KS (1998) Unusual nonepithelial tumors of the head and neck. In: Perez CA, Brady LW (eds) Principles and practice of radiation oncology, 3rd edn. Lippincott-Raven, Philadelphia, pp 1095–1134
Sakata K, Aoki Y, Tago M, Karasawa K, Nakagawa K, Hasegawa K (1998) Radiotherapy of bone metastases of a spinal meningeal hemangiopericytoma. Strahlenther Onkol 174:217–219
Salvati M, Ciappetta P, Artico M, Raco A, Aldo F (1991) Intraspinal hemangioma: case report and review of the literature. Neurosurg Rev 14:309–313
Scott M, Kellett G, Peale A (1974) Angioblastic meningioma (hemangiopericytoma) of the cerebellar fossa with metastases to the temporal bone and the lumbar spine. Surg Neurol 2:35–38
Sellke FW, Laszewski MJ, Robinson RA, Davis R, Rossi NP (1991) Hemangiopericytoma of the sternum. Arch Pathol Lab Med 115:242–244
Shklar G, Meyer I (1965) Vascular tumors of the mouth and jaw. Oral Surg 19:335–358
Simon R, Greene RC (1964) Perirenal hemangiopericytoma. A case associated with hypoglycaemia. J Am Med Assoc 189(21):155–156
Staples JJ, Robinson RA, Wen BC, Hussey DH (1990) Hemangiopericytoma—the role of radiotherapy. Int J Radiat Oncol Biol Phys 19:445–451
Stout AP, Murray MR (1942) Hemangiopericytoma: a vascular tumor featuring Zimmerman’s pericytes. Ann Surg 116:26–33
Stout AP, Cassel C (1943) Hemangiopericytoma of the omentum. Surgery 13:578–581
Uemura S, Kuratsu J, Hamada J, Yoshioka S, Kochi M, Ushio Y et al (1992) Effect of radiation therapy against intracranial hemangiopericytoma. Neurol Med Chir 32:328–332
Zimmermann KW (1923) Der Feinere Eau der Blutcapillaren. Z Anat Entw Gesh 68:29
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Kumar, R., Vaid, V.K., Kumar, V. et al. Hemangiopericytoma of thoracic spine: a rare bony tumor. Childs Nerv Syst 23, 1215–1219 (2007). https://doi.org/10.1007/s00381-007-0372-z
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DOI: https://doi.org/10.1007/s00381-007-0372-z