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Monstrous craniopharyngioma

Case presentations and term proposal

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Abstract

Introduction

Craniopharyngiomas (CF) are benign tumors, which can be cured by total resection; however, this is not always possible to achieve, thus leading to tumor recurrence. When these tumors achieve disproportionate growth, the treatment is even more difficult, fortunately grotesque CF are not frequent, making experience and data collection more arduous to obtain.

Case reports

Four patients are presented here to illustrate the need for the use of a new term, “monstrous craniopharyngioma,” which is proposed with the aim of making the evaluation of the different kinds of treatment available more accurate.

Conclusions

Craniopharyngiomas that have grown into more than one cranial fossa with mixed solid and cystic components pose a special challenge for resection, and therefore a systematic classification and approach are required in order to obtain the best surgical results.

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References

  1. Adamson TE, Wiestler OD, Kleihues P, Yasargil MG (1990) Correlation of clinical and pathological features in surgically treated craniopharyngiomas. J Neurosurg 73:12–17

    Google Scholar 

  2. AlMefty O, Hassounah M, Weaver P, Sakati N, Jinkins JR, Fox JL (1985) Microsurgery for giant craniopharyngiomas in children. Neurosurgery 17:585–595

    Google Scholar 

  3. Backlund EO (1994) Treatment of craniopharyngiomas: the multimodality approach. Pediatr Neurosurg 21 [Suppl 1]:82–89

    Google Scholar 

  4. Buhl R, Lang EW, Barth H, Mehdorn HM (2000) Giant cystic craniopharyngiomas with extension into the posterior fossa. Childs Nerv Syst 16:138–142

    Google Scholar 

  5. Carmel PW, Antunes JL, Change CH (1982) Craniopharyngiomas in children. Neurosurgery 11:382–389

    Google Scholar 

  6. Connolly E Jr, Christopher JW, Carmel PW (1997) Giant posterior fossa cystic craniopharyngiomas presenting with hearing loss. Surg Neurol 47:291–299

    Google Scholar 

  7. Fujimoto Y, Matsushita H, Velasco O, Rosemberg S, Plese JP, Marino R Jr (2002) Craniopharyngioma involving the infrasellar region. Pediatr Neurosurg 37:210–216

    Google Scholar 

  8. Goyal A, Singh AK, Sinha S (2002) Giant cystic craniopharyngioma with posterior fossa extension. Pediatr Neurosurg 37:50–51

    Google Scholar 

  9. Hader WJ, Steinbok P, Hukin J, Fryer C (2000) Intratumoral therapy with bleomycin for cystic craniopharyngiomas in children. Pediatr Neurosurg 33:211–218

    Google Scholar 

  10. Hoffman HJ (1994) Surgical management of craniopharyngioma. Pediatr Neurosurg 21 [Suppl 1]:44–49

    Google Scholar 

  11. Hoffman HJ, Kestle JRW (1994) Craniopharyngiomas. In: Cheek WR (ed) Pediatric neurosurgery, 3rd edn. Saunders, Philadelphia, pp 418–428

    Google Scholar 

  12. Hoffman HJ, De Silva M, Humphreys RP, Drake JM, Smith ML, Blaser SL (1992) Aggressive surgical management of craniopharyngiomas in children. J Neurosurg 76:47–52

    Google Scholar 

  13. Hoffman HJ, De Silva M, Humphreys RP, Drake JM, Smith ML, Blaser SI (1992) Aggressive surgical management of craniopharyngiomas in children. J Neurosurg 76:47–52

    Google Scholar 

  14. Link MJ, Driscoll CL, Giannini C (2002) Isolated, giant cerebellopontine angle craniopharyngioma in a patient with Gardner syndrome: case report. Neurosurgery 51:221–225

    Google Scholar 

  15. Matson DD, Crigler JF Jr (1969) Management of craniopharyngiomas in childhood. J Neurosurg 30:377–390

    Google Scholar 

  16. Miller DC (1994) Pathology of craniopharyngiomas: clinical import of pathological findings. Pediatr Neurosurg 21 [Suppl 1]:11–17

    Google Scholar 

  17. Mottolese C, Stan H, Hermier M, Berlier P, Convert J, Frappaz D, Lapraz C (2001) Intracystic chemotherapy with bleomycin in the treatment of craniopharyngiomas. Childs Nerv Sys 17:724–730

    Google Scholar 

  18. Parent AD, Fleischer AS, Marc JA, Ball TI (1977) Giant craniopharyngioma evaluated by computerized axial tomography. J Pediatr Surg 12:251–253

    Google Scholar 

  19. Sanford RA (1994) Craniopharyngioma: results of survey of the American Society of Pediatric Neurosurgery. Pediatr Neurosurg 21 [Suppl 1]:39–43

    Google Scholar 

  20. Sener RN (1994) Giant craniopharyngioma extending to the anterior cranial fossa and nasopharynx. Am J Roentgenol 162:441–442

    Google Scholar 

  21. Steno J (1985) Microsurgical topography of craniopharyngiomas. Acta Neurochir Suppl 35:94–100

    Google Scholar 

  22. Sung DI, Chang CH, Harisiadis L, Ronsenstein LM (1981) Treatment results of craniopharyngiomas. Cancer 47:847–852

    Google Scholar 

  23. Sutton LN (1994) Vascular complications of surgery for craniopharyngioma and hypothalamic glioma. Pediatr Neurosurg 21 [Suppl 1]:124–128

    Google Scholar 

  24. Sweet WH (1994) History of surgery of craniopharyngiomas. Pediatr Neurosurg 21 [Suppl 1]:28–38

    Google Scholar 

  25. Symon L, Sprich W (1985) Radical excision of craniopharyngioma: results in 20 patients. J Neurosurg 62:174–181

    Google Scholar 

  26. Szeifert GT, Julow J, Szabolcs M, Slowik F, Balint K, Pasztor E (1991) Secretory component of cystic craniopharyngiomas: a mucino-histochemical and electron-microscopic study. Surg Neurol 36:286–293

    Google Scholar 

  27. Weiner HL, Wisoff JH, Rosenberg ME, Kupersmith MJ, Cohen H, Zagzag D et al (1994) Craniopharyngiomas: a clinicopathological analysis of factors predictive of recurrence and functional outcome. Neurosurgery 35:1001–1011

    Google Scholar 

  28. Wisoff JH (1994) Surgical management of recurrent craniopharyngiomas. Pediatr Neurosurg 21 [Suppl 1]:108–113

    Google Scholar 

  29. Yasargil MG, Curcic M, Kis M, Siegernthaler G, Teddy PJ, Roth P (1990) Total removal of craniopharyngiomas. Approaches and long-term results in 144 patients. J Neurosurg 73:3–11

    Google Scholar 

  30. Young SC, Zimmerman RA, Nowell MA, Bilaniuk LT, Hackney DB, Grossman RI, Goldberg HI (1987) Giant cystic craniopharyngiomas. Neuroradiology 29:468–473

    Google Scholar 

  31. Zang YQ, Wang CC, Ma ZY (2002) Pediatric craniopharyngiomas: clinicomorphological study of 189 cases. Pediatr Neurosurg 36:80–84

    Google Scholar 

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Correspondence to Humberto Trejos.

Additional information

A commentary on this paper is available at http://dx.doi.org/10.1007/s00381-004-1102-4

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Trejos, H., Caceres, A. & Segura, J.L. Monstrous craniopharyngioma. Childs Nerv Syst 21, 1049–1053 (2005). https://doi.org/10.1007/s00381-004-1101-5

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  • DOI: https://doi.org/10.1007/s00381-004-1101-5

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