Abstract
Introduction
Meningiomas, especially papillary meningiomas, are rare tumours in childhood and adolescence. They are histologically classified as atypical.
Case report
We present a 15-year-old girl with a cystic papillary meningioma extending from the infratentorial to the supratentorial region extracranially. After a two-stage gross total resection combined with fractionated radiotherapy of a small residual tumour in the infratemporal fossa, the clinical course was stable for at least 4 years. Then a new infratentorial cystic papillary meningioma with a histological change in tumour malignancy was recognised within only 1 year.
Discussion
Besides the rare histology of a cystic papillary meningioma in an adolescent, the case is remarkable due to the considerable extent of the tumour and the irregular course with rapid regrowth and change into malignancy after an initially stable and benign course. For a comparison, the current literature is reviewed and discussed with regard to sex and age distribution, histopathological features, clinical course and therapeutical options.
Similar content being viewed by others
References
Amirjamshidi A, Mehrazin M, Abbassioun K (2000) Meningiomas of the central nervous system occurring below the age of 17: report of 24 cases not associated with neurofibromatosis and review of literature. Childs Nerv Syst 16:406–416
Davidson GS, Hope J (1989) Meningeal tumors of childhood. Cancer 63:1205–1210
Di Rocco C, Di Rienzo A (1999) Meningiomas in childhood. Crit Rev Neurosurg 9:180–188
Dziuk TW, Woo S, Butler EB, Thornby J, Grossman R, Dennis WS, Lu H, Carpenter LS, Chiu JK (1998) Malignant meningioma: an indication for initial aggressive surgery and adjuvant radiotherapy. J Neurooncol 37:177–188
Ferrante L, Acqui M, Artico M, Mastronardi L, Rocchi G, Fortuna A (1989) Cerebral meningiomas in children. Childs Nerv Syst 5:83–86
Flickinger JC, Kondziolka D, Maitz AH, Lunsford LD (2003) Gamma knife radiosurgery of imaging-diagnosed intracranial meningioma. Int J Radiat Oncol Biol Phys 56:801–806
Germano A, Galatioto S, La Rosa G, Caffo M, Cardia E (1997) Xanthomatous posterior pyramid meningioma in a 2-year-old girl. Childs Nerv Syst 13:406–411
Goldsmith BJ, Wara WM, Wilson CB, Larson DA (1994) Postoperative irradiation for subtotally resected meningiomas. J Neurosurg 80:195–201
Goyal LK, Suh H, Mohan DS, Prayson RA, Lee J, Barnett GH (2000) Local control and overall survival in atypical meningioma: a retrospective study. Int J Radiat Oncol Biol Phys 46:57–61
Herz DA, Shapiro K, Shulman K (1980) Intracranial meningiomas of infancy, childhood and adolescence. Childs Brain 7:43–56
Kleihues P, Cavenee WK (2000) Tumours of the nervous system. Pathology and genetics. IARC, Lyon
Kros JM, Cella F, Bakker SLM, Paz D, Geuze Y, Egeler RM (2000) Papillary meningioma with pleural metastasis: case report and literature review. Acta Neurol Scand 102:200–202
Lirng JF, Enterline DS, Tien RD, Fuchs H, Friedman HS, Ellington KS, McLendon RP (1995) MRI of papillary meningiomas in children. Pediatr Radiol 25:S9–S13
Malluci CL, Parkes SE, Barber P, Powell J, Stevens MCG, Walsh AR, Hockley AD (1996) Pediatric meningeal tumours. Childs Nerv Syst 12:582–589
Meinsma-v.d.Tuin M, Molenaar WM, Mooij JJA (2000) Spinal papillary meningioma: a case report and review of the literature. Acta Neurochir (Wien) 142:703–708
Nakamura M, Roser F, Michel J, Jacobs C, Samii M (2003) The natural history of incidental meningiomas. Neurosurgery 53:62–71
Sandberg DI, Edgar MA, Resch L, Rutka JT, Becker LE, Souweidane MM (2001) MIB-1 staining index of pediatric meningiomas. Neurosurgery 48:590–595
Shah MV, Haines SJ (1992) Pediatric skull, skull base, and meningeal tumors. Neurosurg Clin N Am 3:893–924
Turgut M, Ocan E, Bertan V (1997) Meningiomas in childhood and adolescence: a report of 13 cases and review of literature. Br J Neurosurg 11:501–507
Vaquero J, Zurita M, Coca S (2002) Cystic papillary meningioma. Neuropathol Appl Neurobiol 28:418–424
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Buschmann, U., Gers, B. & Hildebrandt, G. Uncommon case of a cystic papillary meningioma in an adolescent. Childs Nerv Syst 21, 322–326 (2005). https://doi.org/10.1007/s00381-004-1017-0
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00381-004-1017-0