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The evolution and future of minimalism in neurological surgery

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Abstract

Introduction

The evolution of the field of neurological surgery has been marked by a progressive minimalism. This has been evident in the development of an entire arsenal of modern neurosurgical enterprises, including microneurosurgery, neuroendoscopy, stereotactic neurosurgery, endovascular techniques, radiosurgical systems, intraoperative and navigational devices, and in the last decade, cellular and molecular adjuvants.

Aims

In addition to reviewing the major developments and paradigm shifts in the cyclic reinvention of the field as it currently stands, this paper attempts to identify forces and developments that are likely to fuel the irresistible escalation of minimalism into the future. These forces include discoveries in computational science, imaging, molecular science, biomedical engineering, and information processing as they relate to the theme of minimalism.

Discussion

These areas are explained in the light of future possibilities offered by the emerging field of nanotechnology with molecular engineering.

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References

  1. Adler JR, Murphy MJ, Chang SD, Hancock SL (1999) Image-guided robotic radiosurgery. Neurosurgery 44:1299–1306

    PubMed  Google Scholar 

  2. Amar AP, Zlokovic BV, Apuzzo MLJ (2003) Endovascular restorative neurosurgery: a novel concept for molecular and cellular therapy of the nervous system. Neurosurgery 52:402–412

    PubMed  Google Scholar 

  3. Apuzzo MLJ (2000) Modernity and the emerging futurism in neurosurgery tempora mutantur nos et mutamur in illis. J Clin Neurosci 7:85–87

    Article  PubMed  Google Scholar 

  4. Apuzzo MLJ (2001) Cellular and molecular neurosurgery: fetal grafting to treat Parkinson’s disease. Neurosurgery 49:575–575

    PubMed  Google Scholar 

  5. Apuzzo MLJ, Liu CY (2001) Things to come. Neurosurgery 49:765–778

    Google Scholar 

  6. Apuzzo MLJ, Liu CY (2002) Honored guest presentation: quid novi? In the realm of ideas—the neurosurgical dialectic. Clin Neurosurg 49:159–187

    PubMed  Google Scholar 

  7. Apuzzo MLJ, Liu CY, Sullivan D, Faccio RA (2002) Honored guest presentation: surgery of the human cerebrum—a collective modernity. Clin Neurosurg 49:27–89

    PubMed  Google Scholar 

  8. Bennett CH, DiVincenzo DP (2000) Quantum information and computation. Nature 404:247–255

    Article  Google Scholar 

  9. Betzig E, Trautman JK, Harris TD, Weiner JS, Kostelak RL (1991) Breaking the diffraction barrier-optical microscopy on a nanometric scale. Science 251:1468–1470

    Google Scholar 

  10. Crommie MF, Lutz CP, Eigler DM (1993) Confinement of electrons to quantum corrals on a metal-surface. Science 262:218–220

    CAS  Google Scholar 

  11. Frietas RA Jr (1999) Nanomedicine: basic capabilities, vol 1. Landes Bioscience, Austin

  12. Hadani M, Spiegelman R, Feldman Z, Berkenstadt H, Ram Z (2001) Novel, compact, intraoperative magnetic resonance imaging-guided system for conventional neurosurgical operating rooms. Neurosurgery 48:799–807

    CAS  PubMed  Google Scholar 

  13. Hopkins LN, Lanzino G, Guterman LR (2001) Treating complex nervous system vascular disorders through a “needle stick”: origins, evolution, and future of neuroendovascular therapy. Neurosurgery 48:463–475

    CAS  PubMed  Google Scholar 

  14. Liu CY, Apuzzo MLJ (2003) The genesis of neurosurgery and the evolution of the neurosurgical operative environment. I. Prehistory to 2003. Neurosurgery 52:3–19

    PubMed  Google Scholar 

  15. Liu CY, Apuzzo MLJ, Tirrell DA (2003) Engineering of the extracellular matrix: working toward neural stem cell programming and neurorestoration—concept and progress report. Neurosurgery 52:1154–1165

    PubMed  Google Scholar 

  16. Liu CY, Spicer M, Apuzzo MLJ (2003) The genesis of neurosurgery and the evolution of the neurosurgical operative environment. II. Concepts for future development, 2003 and beyond. Neurosurgery 52:20–33

    PubMed  Google Scholar 

  17. Reed MA, Tour JM (2000) Computing with molecules. Sci Am 282:86–93

    CAS  Google Scholar 

  18. Roy S, Ferrara LA, Fleischman AJ, Benzel EC (2001) Microelectromechanical systems and neurosurgery: a new era in a new millennium. Neurosurgery 49:779–797

    CAS  PubMed  Google Scholar 

  19. Rutka JT, Taylor M, Mainprize T, Langlois A, Ivanchuk S, Mondal S, Dirks P (2000) Molecular biology and neurosurgery in the third millennium. Neurosurgery 46:1034–1051

    CAS  PubMed  Google Scholar 

  20. Soong RK, Bachand GD, Neves HP, Olkhovets AG, Craighead HG, Montemagno CD (2000) Powering an inorganic nanodevice with a biomolecular motor. Science 290:1555–1558

    Article  CAS  PubMed  Google Scholar 

  21. Spicer MA, Apuzzo MLJ (2003) Virtual reality surgery: neurosurgery and the contemporary landscape. Neurosurgery 52:489–496

    PubMed  Google Scholar 

  22. Various (2001) Human genome issue. Science 291:1145–1434

    Google Scholar 

  23. Various (2001) Human genome issue. Nature 409:813–960

    Article  PubMed  Google Scholar 

  24. Various (2000) Issues in nanotechnology. Science 290:1523–1545

    Article  Google Scholar 

  25. Zlokovic BV, Apuzzo MLJ (1997) Cellular and molecular neurosurgery: pathways from concept to reality. I. Target disorders and concept approaches to gene therapy of the central nervous system. Neurosurgery 40:789–803

    CAS  PubMed  Google Scholar 

  26. Zlokovic BV, Apuzzo MLJ (1997) Cellular and molecular neurosurgery: pathways from concept to reality. II. Vector systems and delivery methodologies for gene therapy of the central nervous system. Neurosurgery 40:805–812

    CAS  PubMed  Google Scholar 

  27. Zlokovic BV, Apuzzo MLJ (1998) Strategies to circumvent vascular barriers of the central nervous system. Neurosurgery 43:877–878

    CAS  PubMed  Google Scholar 

Download references

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Correspondence to Michael L. J. Apuzzo.

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Liu, C.Y., Wang, M.Y. & Apuzzo, M.L.J. The evolution and future of minimalism in neurological surgery. Childs Nerv Syst 20, 783–789 (2004). https://doi.org/10.1007/s00381-004-0931-5

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  • DOI: https://doi.org/10.1007/s00381-004-0931-5

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