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Fetal MRI: normal gestational landmarks for cerebral biometry, gyration and myelination

Child's Nervous System volume 19, pages 422–425 (2003)Cite this article

Abstract

Purpose

Up until the last 10 years, normal cerebral gestational landmarks were assessed by ultrasonographic and fetopathologic studies. The purpose of this paper is to display the possibilities provided by fetal MRI in the evaluation of fetal cerebral biometry, normal sulcation and myelination.

Methods

Two hundred and twenty-five fetuses (with a normal brain) were studied prospectively using a standardised method. The gestational age ranged from 22 to 38 weeks. The main data concerning biometry of various cerebral structures at those terms are given .

Discussion

In contrast to ultrasound, MRI allows measurements of brain (and not skull), which are available independently of the position of the fetal head. The timing of the appearance of the different sulci is also available using MRI. It is considered to be a good marker of fetal brain maturation. The biochemical modifications contemporary to myelination make it possible to evaluate this phenomenon in the fetal brain using MRI.

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Fig. 1a–c.

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Authors and Affiliations

  1. Department of Paediatric Imaging, Hôpital Robert Debré, 48 boulevard Sérurier, 75019, Paris, France

    Catherine Garel, Emmanuel Chantrel, Monique Elmaleh, Hervé Brisse & Guy Sebag

Authors
  1. Catherine Garel
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  2. Emmanuel Chantrel
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  3. Monique Elmaleh
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  4. Hervé Brisse
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  5. Guy Sebag
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Correspondence to Catherine Garel.

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Garel, C., Chantrel, E., Elmaleh, M. et al. Fetal MRI: normal gestational landmarks for cerebral biometry, gyration and myelination. Childs Nerv Syst 19, 422–425 (2003). https://doi.org/10.1007/s00381-003-0767-4

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  • DOI: https://doi.org/10.1007/s00381-003-0767-4

Keywords

  • Brain anatomy
  • Brain growth and development
  • Brain volume
  • Fetal brain
  • Fetal central nervous system
  • MRI
  • Fetal MRI