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Neurosurgical treatment of meningiomas in children and young adults

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Object: We studied the frequency, functional outcome, association with neurofibromatosis (NF) and relapse in patients operated on for meningiomas at age 0–20 years in three Norwegian centers between 1972 and 1999. Methods: Information was collected by examining case notes and histology records, conducting telephone interviews and performing new radiological investigations. Twenty-seven patients were identified. Five had NF, and all 5 developed multiple tumors. In non-NF patients, relapse occurred in 2 out of 19 who underwent total tumor resection, and in all 3 whose surgery was nonradical. There was 1 postsurgical death, and no other major complications. Most patients had few complaints or none at all resulting from their previous tumor or treatment. Conclusions: Meningiomas without NF have a good prognosis in children and young adults if the tumor can be removed radically. However, relapse can occur many years after the primary operation.

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Lund-Johansen, M., Scheie, D., Muller, T. et al. Neurosurgical treatment of meningiomas in children and young adults. Child's Nerv Syst 17, 719–723 (2001).

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