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Systemic arterial pulsatility (SAPi) in advanced heart failure: a novel hemodynamic risk stratification tool

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Abstract

Systemic arterial pulsatility index (SAPi) is a novel hemodynamic marker for ventriculo-arterial coupling (VAC), as it integrates the contractile properties of the left ventricle with the aortic impendence. SAPi can identify heart failure patients at increased risk for adverse events. Systemic pulsatility decreases as heart failure progresses, and there is a decrease in pulse pressure accompanied by an increase in left ventricular filling pressure. Decreasing SAPi is associated with worse prognosis in advanced heart failure patients.

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Data availability statement

We acknowledge the help of the National Heart, Lung and Blood Institutes for making available the database used in this secondary analysis.

References

  1. Mazimba S, Mwansa H, Breathett K, Strickling JE, Shah K, McNamara C, Mehta N, Kwon Y, Lamp J, Feng L, Tallaj J, Pamboukian S, Mubanga M, Matharoo J, Lim S, Salerno M, Mwansa V, Bilchick KC (2022) Systemic arterial pulsatility index (SAPi) predicts adverse outcomes in advanced heart failure patients. Heart Vessels 37(10):1719–1727

    Article  PubMed  Google Scholar 

  2. Oh JK (2005) Echocardiography as a noninvasive Swan-Ganz catheter. Circulation 111(24):3192–3194

    Article  PubMed  Google Scholar 

  3. Chirinos JA, Sweitzer N (2017) Ventricular-arterial coupling in chronic heart failure. Card Fail Rev 3(1):12–18

    Article  PubMed  PubMed Central  Google Scholar 

  4. Lim HS, Gustafsson F (2020) Pulmonary artery pulsatility index: physiological basis and clinical application. Eur J Heart Fail 22(1):32–38

    Article  PubMed  Google Scholar 

  5. Mazimba S, Welch TS, Mwansa H, Breathett KK, Kennedy JLW, Mihalek AD, Harding WC, Mysore MM, Zhuo DX, Bilchick KC (2019) Haemodynamically derived pulmonary artery pulsatility index predicts mortality in pulmonary arterial hypertension. Heart Lung Circ 28(5):752–760

    Article  PubMed  Google Scholar 

  6. Ommen SR, Nishimura RA, Appleton CP, Miller FA, Oh JK, Redfield MM, Tajik AJ (2000) Clinical utility of doppler echocardiography and tissue doppler imaging in the estimation of left ventricular filling pressures: a comparative simultaneous doppler-catheterization study. Circulation 102(15):1788–1794

    Article  CAS  PubMed  Google Scholar 

  7. Kane CJ, Salama AA, Pislaru C, Kane GC, Pislaru SV, Lin G (2022) Low pulmonary artery pulsatility index by echocardiography is associated with increased mortality in pulmonary hypertension. J Am Soc Echocardiogr. https://doi.org/10.1016/j.echo.2022.09.003

    Article  PubMed  Google Scholar 

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Correspondence to Sula Mazimba.

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Mazimba, S., Bilchick, K.C. Systemic arterial pulsatility (SAPi) in advanced heart failure: a novel hemodynamic risk stratification tool. Heart Vessels 38, 1093–1094 (2023). https://doi.org/10.1007/s00380-022-02217-6

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  • DOI: https://doi.org/10.1007/s00380-022-02217-6

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