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Two cases with past Kawasaki disease developing acute myocardial infarction in their thirties, despite being regarded as at low risk for coronary events

Abstract

Two patients after Kawasaki disease (KD) developed acute myocardial infarction in their thirties, though coronary artery follow-up were deemed unnecessary because of apparently angiographic normal coronary arteries in their children more than 1-year after acute KD. Angiographic findings of apparently normal coronary arteries in the late period after acute KD are possible to mislead their prognoses. It should be recognized that coronary aneurysms can often regress in the late period. There is ongoing controversy about the therapeutic strategy in patients whose coronary aneurysms regressed within several years after acute KD. Coronary computed tomography angiography and flow-mediated dilatation might be useful for the detection of mild sequelae of KD non-invasively.

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We have received no financial support, and have no financial relationship with industry.

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Correspondence to Hideki Kawai.

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Kawai, H., Takakuwa, Y., Naruse, H. et al. Two cases with past Kawasaki disease developing acute myocardial infarction in their thirties, despite being regarded as at low risk for coronary events. Heart Vessels 30, 549–553 (2015). https://doi.org/10.1007/s00380-014-0541-4

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  • DOI: https://doi.org/10.1007/s00380-014-0541-4

Keywords

  • Kawasaki disease
  • Coronary computed tomography angiography
  • Flow-mediated dilatation
  • Acute myocardial infarction