Abstract
In children, up to 10% of the cases of arterial hypertension may be caused by a renovascular disease. The etiology of this renovascular disease is most of the time due to a fibromuscular dysplasia (FMD), which causes a noninflammatory intimal-medial fibroplasia leading to luminal compromise. Percutaneous transluminal angioplasty of FMD is a worldwide-accepted treatment modality for this serious arterial disease with, so far, good safety and long-term efficacy data. Once FMD involves several arterial compartments leading to symptoms the outcomes are poor. Herein we report the case of a 3½-year-old boy with severe arterial hypertension and abdominal angina due to a diffuse multivisceral FMD involvement, successfully managed by a percutaneous angioplasty approach using a new balloon catheter for plaque modulation.
Similar content being viewed by others
References
Bayazit AK, Yalcinkaya F, Cakar N, Duzova A, Bircan Z, Bakkaloglu A, Canpolat N, Kara N, Sirin A, Ekim M, Oner A, Akman S, Mir S, Baskin E, Poyrazoglu HM, Noyan A, Akil I, Bakkaloglu S, Soylu A (2007) Reno-vascular hypertension in childhood: a nationwide survey. Pediatr Nephrol 22(9):1327–1333
Slovut DP, Olin JW (2004) Fibromuscular dysplasia. N Engl J Med 350(18):1862–1871
Kincaid OW, Davis GD, Hallermann FJ, Hunt JC (1968) Fibromuscular dysplasia of the renal arteries. Arteriographic features, classification, and observations on natural history of the disease. Am J Roentgenol Radium Ther Nucl Med 104(2):271–282
Stokes JB, Bonsib SM, McBride JW (1996) Diffuse intimal fibromuscular dysplasia with multiorgan failure. Arch Intern Med 156(22):2611–2614
McCook TA, Mills SR, Kirks DR, Heaston DK, Seigler HF, Malone RB, Osofsky SG (1980) Percutaneous transluminal renal artery angioplasty in a 3 1/2-year-old hypertensive girl. J Pediatr 97(6):958–960
Tegtmeyer CJ, Elson J, Glass TA, Ayers CR, Chevalier RL, Wellons HA Jr, Studdard WE Jr (1982) Percutaneous transluminal angioplasty: the treatment of choice for renovascular hypertension due to fibromuscular dysplasia. Radiology 143(3):631–637
Shroff R, Roebuck DJ, Gordon I, Davies R, Stephens S, Marks S, Chan M, Barkovics M, McLaren CA, Shah V, Dillon MJ, Tullus K (2006) Angioplasty for renovascular hypertension in children: 20-year experience. Pediatrics 118(1):268–275
Courtel JV, Soto B, Niaudet P, Gagnadoux MF, Carteret M, Quignodon JF, Brunelle F (1998) Percutaneous transluminal angioplasty of renal artery stenosis in children. Pediatr Radiol 28(1):59–63
Iida O, Nanto S, Uematsu M, Morozumi T, Akahori H, Nagata S (2007) Endovascular therapy for limb salvage in a case of critical lower limb ischemia resulting from fibromuscular dysplasia. J Vasc Surg 46(4):803–807
Scheinert D, Peeters P, Bosiers M, O’sullivan G, Sultan S, Gershony G (2007) Results of the multicenter first-in-man study of a novel scoring balloon catheter for the treatment of infra-popliteal peripheral arterial disease. Catheter Cardiovasc Interv 70(7):1034–1039
de Ribamar Costa J Jr, Mintz GS, Carlier SG, Mehran R, Teirstein P, Sano K, Liu X, Lui J, Na Y, Castellanos C, Biro S, Dani L, Rinker J, Moussa I, Dangas G, Lansky AJ, Kreps EM, Collins M, Stone GW, Moses JW, Leon MB (2007) Nonrandomized comparison of coronary stenting under intravascular ultrasound guidance of direct stenting without predilation versus conventional predilation with a semi-compliant balloon versus predilation with a new scoring balloon. Am J Cardiol 100(5):812–817
Towbin RB, Pelchovitz DJ, Baskin KM, Cahill AM, Roebuck DJ, McClaren CA (2007) Cutting balloon angioplasty in children with resistant renal artery stenosis. J Vasc Interv Radiol 18(5): 663–669
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bonvini, R.F., Rastan, A., Sixt, S. et al. Diffuse fibromuscular dysplasia successfully treated with scoring balloon angioplasty in a 3-year-old boy. Heart Vessels 24, 460–462 (2009). https://doi.org/10.1007/s00380-009-1147-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00380-009-1147-0