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Nonintrusive pressure measurement in microfluidic systems via backscattering interferometry

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Abstract

Measurement of pressure in microfluidic systems typically requires intrusion into the channel, rendering direct pressure and fluid flow rate measurements impractical outside of a laboratory environment. A nonintrusive measurement technique has been successfully developed to measure fluid pressure in both gas and liquids in microchannels. The technique, which consists of an unfocused laser beam impinging a microchannel to generate interferometric fringes, contains information on both channel wall deflection and changes in refractive index of the liquid or gas. The effects can be isolated through interpretation of fringe shift and changes in fringe morphology. Using finite element analysis to determine microchannel wall deflection in conjunction with refractive index data enables accurate quantification of pressures in microchannels.

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References

  • Adrian RJ (2011) Particle image velocimetry. Cambridge University Press, Cambridge, New York

    Google Scholar 

  • Birch KP, Downs MJ (1993) An updated Edlén equation for the refractive index of air. Metrologia 30:155–162

    Article  Google Scholar 

  • Born M, Wolf E (1983) Principles of optics, 6th edn. Pergamon, Oxford

    Google Scholar 

  • Bornhop DJ (1994) Laser-based refractive index detector using backscatter, U.S. Patent #5,325,170.

  • Bucaro JA, Lagakos N, Houston BH, Jarzynski J, Zalalutdinov M (2005) Miniature, high performance, low-cost fiber optic microphone. J Acoust Soc Am 118(3):1406–1413

    Article  Google Scholar 

  • Dorsey NE (1940) Properties of ordinary water-substance. American chemical society monograph series. Reinhold Publishing Corporation, New York

    Google Scholar 

  • Edlén B (1966) The refractive index of air. Metrologia 2:71–80

    Article  Google Scholar 

  • Florea M (2000) Using a differential refractive index detector as a pressure transducer for online viscometry in exclusion chromatography. J Chromatogr A 878(1):1–15

    Article  MathSciNet  Google Scholar 

  • Francon M (1966) Optical interferometry. Academic Press, New York, London

    Google Scholar 

  • Fultz D (2007) Nonintrusive pressure measurement in microchannels. M.S. Thesis, Michigan Technological University.

  • Ganesan K (2002) Optical Detection of air bubbles trapped in a micro-capillary pore using a laser interferometric backscatter technique. M.S. Thesis, University of Tennessee - Knoxville.

  • Greywall DS (1997) Micromechanical light modulators, pressure gauges, and thermometers attached to optical fibers. J Micromec Microeng 7(4):343

    Article  Google Scholar 

  • Hernandez J, Allen JS (2011) Visualization of flow near a steadily advancing Meniscus. In: 9th International Symposium on Particle Image Velocimetry (PIV11), Kobe, Japan

  • Jin S, Park J, Yoo JY, Breuer KS (2003) Near-wall PTV measurements using evanescent wave illumination. In: 5th International Symposium on Particle Image Velocimetry (PIV03), Busan, Korea

  • Kihm K (2011) Near-field characterization of micro/nano-scaled fluid flows. Springer, New York

    Book  Google Scholar 

  • Lauer JL, Miller JPH (1947) An instrument for the measurement of the index of refraction of liquids in the wave-length range 200 μm to 1000 μm. J Opt Soc Am 37(8):664–668

    Article  Google Scholar 

  • Markov D, Begari D, Bornhop DJ (2002) Breaking the 10−7 barrier for RI measurements in nanoliter volumes. Anal Chem 74(20):5438–5441

    Article  Google Scholar 

  • Markov D, Dotson S, Wood S, Bornhop D (2004) Nonintrusive fluid flow measurements in microfluidic channels with backscatter interferometry. Electrophoresis 25:3805–3809

    Article  Google Scholar 

  • Park JS, Choi CK, D Kihm K (2004) Optically sliced micro-PIV using confocal laser scanning microscopy (CLSM). Exp Fluids 37(1):105–119

  • Probstein RF (1994) Physicochemical hydrodynamics: an introduction. Wiley-Interscience,  Hoboken

    Book  Google Scholar 

  • Santiago JG, Wereley ST, Meinhart CD, Beebe DJ, Adrian RJ (1998) A particle image velocimetry system for microfluidics. Exp Fluids 25:316–319

    Article  Google Scholar 

  • Sorensen H (2006) Self calibrating interferometric sensor. PhD Dissertation, Technical University of Denmark

  • Swinney K, Bornhop D (2001) Noninvasive picoliter volume thermometry based on backscatter interferometry. Electrophoresis 22:2032–2036

    Article  Google Scholar 

  • Swinney K, Markov D, Bornhop DJ (2000) Chip-scale universal detection based on backscatter interferometry. Anal Chem 72(13):2690–2695

    Article  Google Scholar 

  • Tarigan HJ, Neill P, Kenmore CK, Bornhop DJ (1996) Capillary-scale refractive index detection by interferometric backscatter. Anal Chem 68(10):1762–1770

    Article  Google Scholar 

  • Wang Z, Bornhop DJ (2005) Dual-capillary backscatter interferometry for high-sensitivity nanoliter-volume refractive index detection with density gradient compensation. Anal Chem 77(24):7872–7877

    Article  Google Scholar 

Download references

Acknowledgments

This research was partially supported by the Michigan Tech Research Excellence Fund.

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Correspondence to Jeffrey S. Allen.

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Fultz, D.W., Allen, J.S. Nonintrusive pressure measurement in microfluidic systems via backscattering interferometry. Exp Fluids 55, 1754 (2014). https://doi.org/10.1007/s00348-014-1754-0

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  • DOI: https://doi.org/10.1007/s00348-014-1754-0

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