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Metastase in der periokulären Region

Metastasis in the periocular region

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Zusammenfassung

Orbitale und periokuläre metastatische Tumoren galten früher als sehr selten. Aber mit der ständigen Aktualisierung von Medikamenten und Nachweismethoden für die Krebsbehandlung werden neue Chemotherapien und Strahlenbehandlungen eingesetzt. Die Lebenserwartung von Krebspatienten ist länger geworden, und periokuläre Metastasen sind immer leichter zu erkennen. Auch unser Wissen über die Metastasen in einer seltenen Lokalisation muss aktualisiert werden. Dieser Beitrag gibt einen Überblick über die Inzidenz, die symptomatische Präsentation, die klinischen Merkmale, die diagnostischen Ansätze und die aktuelle Behandlung von Metastasen der Orbita und der okulären Adnexe bei diesen Patienten.

Abstract

Orbital and periocular metastatic tumors used to be considered very rare; however, with the constant updating of drugs and detection methods for cancer treatment, new chemotherapies and radiation treatments are being used. The life expectancy of cancer patients has become longer and periocular metastases are becoming easier to detect. Our knowledge of this rare disease of metastases also needs to be updated. This article reviews the incidence, symptomatic presentation, clinical features, diagnostic approaches and current treatment of metastatic tumors of the orbit and ocular adnexa in these patients.

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Authors and Affiliations

  1. Zentrum für Augenheilkunde, Medizinische Fakultät und Uniklinik Köln, Universität zu Köln, Kerpener Str. 62, 50937, Köln, Deutschland

    Yating Liu, Alexander C. Rokohl,  Wanlin Fan &  Ludwig M. Heindl

  2. Centrum für Integrierte Onkologie (CIO), Aachen-Bonn-Köln-Düsseldorf, Köln, Deutschland

    Alexander C. Rokohl &  Ludwig M. Heindl

  3. Klinik für Hämatologie, Onkologie und Immunologie, Klinikum Region Hannover, Hannover, Deutschland

    Martin R. Müller

  4. Klinik für Augenheilkunde, Klinikum Chemnitz, Chemnitz, Deutschland

    Vinodh Kakkassery

Authors
  1. Yating Liu
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  2. Alexander C. Rokohl
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  3. Martin R. Müller
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  4. Vinodh Kakkassery
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  5. Wanlin Fan
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  6. Ludwig M. Heindl
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Corresponding authors

Correspondence to Wanlin Fan or Ludwig M. Heindl.

Ethics declarations

Interessenkonflikt

Y. Liu, A.C. Rokohl, M.R. Müller, V. Kakkassery, W. Fan und L.M. Heindl geben an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autor/-innen keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien. Für Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts, über die Patient/-innen zu identifizieren sind, liegt von ihnen und/oder ihren gesetzlichen Vertretern/Vertreterinnen eine schriftliche Einwilligung vor.

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Hinweis des Verlags

Der Verlag bleibt in Hinblick auf geografische Zuordnungen und Gebietsbezeichnungen in veröffentlichten Karten und Institutsadressen neutral.

Die Autor*innen Wanlin Fan und Ludwig M. Heindl haben zu gleichen Teilen zum Manuskript beigetragen und teilen sich die Letztautorenschaft.

Prof. Ludwig M. Heindl und Dr. Wanlin Fan teilen sich die Erstautorenschaft.

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Liu, Y., Rokohl, A.C., Müller, M.R. et al. Metastase in der periokulären Region. Ophthalmologie 121, 366–373 (2024). https://doi.org/10.1007/s00347-024-02035-3

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