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Rolle des Glaskörpers für Erkrankungen benachbarter Strukturen

The role of the vitreous body in diseases of neighboring structures

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Zusammenfassung

Hintergrund und Fragestellung

Das vitreoretinale Interface, also der Raum zwischen Glaskörper und Netzhaut, ist nicht nur einfach ein Zwischenraum, sondern Schauplatz mannigfaltiger Pathologien, bei denen der Glaskörper Einfluss auf seine benachbarten Strukturen nimmt.

Methoden

Es erfolgte eine selektive Literaturrecherche in Pubmed und aktuellen Buchbeiträgen.

Ergebnisse

Im vorliegenden Beitrag wird der Einfluss auf die zentrale Netzhaut bei der vitreomakulären Traktion, der Entstehung des Makulaforamens und der epiretinalen Gliose sowie die Beteiligung bei der neovaskulären alterskorrelierten Makuladegeneration beschrieben. In der Netzhautperipherie ist der Glaskörper bei der Entstehung der Netzhautforamina beteiligt, und auch bei der proliferativen Vitreoretinopathie und diabetischen Retinopathie ist der Einfluss essenziell. Dem Zusammenhang zwischen Glaskörper und der Eintrübung der natürlichen Linse wird oft wenig Beachtung geschenkt.

Diskussion

Die Glaskörperchirurgie vor allem im Zeitalter der medikamentösen Vitreolyse kommt nicht ohne die Kenntnis der pathophysiologischen Zusammenhänge zwischen Glaskörper und seinen benachbarten Strukturen aus.

Abstract

Background

The vitreoretinal interface is not merely the space between the vitreous body and the retina but it is also a site for highly complex pathologies with the vitreous body exerting an influence on all the neighbouring structures.

Methods

A literature search was performed in Pubmed and current book articles

Results

This review article highlights the role of the vitreous body in vitreomacular adhesion and traction, in the development of macular holes and epiretinal membranes as well as its role in age-related macular degeneration. In the retinal periphery the vitreous structures play a pivotal role in retinal tears and detachment as well as in diabetic and other proliferative vitreoretinopathies. The role of the vitreous bodyin the emergence of various forms of cataract is often underestimated.

Discussion

Vitreo-etinal surgeons should thoroughly understand the pathophysiological relationship between the vitreous body and the neighboring structures, especially in the era of medical vitreolysis.

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Authors and Affiliations

  1. Augenklinik des Klinikums Stuttgart, Kriegsbergstraße 60, 70174, Stuttgart, Deutschland

    K. Gekeler & F. Gekeler

  2. Universitäts-Augenklinik Tübingen, Tübingen, Deutschland

    K. Gekeler & F. Gekeler

  3. Augenklinik des Allgemeinen Krankenhauses der Stadt Linz, Medizinische Fakultät der Johannes Kepler Universität Linz, Linz, Österreich

    S. Priglinger & C. Priglinger

  4. Augenklinik der Ludwig-Maximilians-Universität München, München, Deutschland

    C. Priglinger

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  1. K. Gekeler
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  3. F. Gekeler
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  4. C. Priglinger
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Correspondence to K. Gekeler.

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K. Gekeler, S. Priglinger, F. Gekeler und C. Priglinger geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

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Gekeler, K., Priglinger, S., Gekeler, F. et al. Rolle des Glaskörpers für Erkrankungen benachbarter Strukturen. Ophthalmologe 112, 564–571 (2015). https://doi.org/10.1007/s00347-015-0056-0

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  • DOI: https://doi.org/10.1007/s00347-015-0056-0

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