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Histologie bei bilateral asymmetrischem vasoproliferativem Tumor der Retina

Histological findings in bilateral asymmetrical vasoproliferative retinal tumor

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Zusammenfassung

Wir präsentieren einen beidseitigen vasoproliferativen Tumor der Netzhaut eines jungen Mannes. Erstsymptom war eine Visusminderung, hervorgerufen durch eine Glaskörperblutung. Am rechten Auge zeigte sich der Befund schwächer ausgeprägt und wurde erfolgreich mittels wiederholter Laser- und Kryokoagulation und Bevazicumab-Injektion behandelt. Der prominentere Tumor am linken Auge führte schließlich zum therapierefraktären, schmerzhaften Sekundärglaukom. Die Netzhautläsion wurde nach Enukleation histologisch und immunhistochemisch aufgearbeitet. Diskutiert werden klinische und histologische Differenzialdiagnosen und Therapieoptionen.

Abstract

We present a case of a bilateral vasoproliferative tumor of the retina in a young man. The first symptom was visual impairment due to vitreous hemorrhage. The right eye showed small tumors which were successfully treated by repeated cryocoagulation, photocoagulation and bevazicumab injection. The tumor in the left eye was larger and eventually led to a painful secondary glaucoma. After enucleation, this tumor was examined histologically and immunohistochemically. The clinical and histological differential diagnoses and therapeutic options are discussed.

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Authors and Affiliations

  1. Klinik für Ophthalmologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, Haus 25, 24105, Kiel, Deutschland

    S. Bajorat, S. Koinzer & J. Roider

  2. Institut für Pathologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Deutschland

    J.H. Bräsen & H.H. Hugo

Authors
  1. S. Bajorat
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  2. S. Koinzer
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  3. J.H. Bräsen
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  4. H.H. Hugo
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  5. J. Roider
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Correspondence to S. Bajorat.

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Bajorat, S., Koinzer, S., Bräsen, J. et al. Histologie bei bilateral asymmetrischem vasoproliferativem Tumor der Retina. Ophthalmologe 109, 1026–1029 (2012). https://doi.org/10.1007/s00347-012-2627-7

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  • DOI: https://doi.org/10.1007/s00347-012-2627-7

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