Skip to main content
Log in

Kataraktoperation

Effekt auf den hinteren Augenabschnitt

Cataract surgery

Effect on the posterior segment of the eye

  • CME Weiterbildung · Zertifizierte Fortbildung
  • Published:
Der Ophthalmologe Aims and scope Submit manuscript

Zusammenfassung

Die Kataraktoperation ist ein sicherer Eingriff mit niedriger Komplikationsrate und guter Erfolgsaussicht. Dennoch beeinflusst sie die Physiologie des Auges. Akut werden Entzündungsmediatoren freigesetzt, intraoperative Druckschwankungen und Verformungen des Auges können Mikrotraumen hervorrufen und die Durchblutung beeinträchtigen. Postoperativ verändern sich die Diffusionsbarrieren und die Geometrie der intraokularen Räume. Insbesondere der Glaskörper unterliegt über die Jahre vermehrten Destruktionen. Klinisch ist das pseudophake zystoide Makulaödem nach Kataraktoperation bekannt. Mehrere Studien bestätigten eine gewisse Progredienz einer diabetischen Retinopathie, v. a. eines diabetischen Makulaödems. Für das Fortschreiten einer Makuladegeneration scheint die Kataraktoperation keine große Rolle zu spielen, das Risiko für eine Netzhautablösung bei Pseudophakie steigt jedoch über mindestens 10 Jahre erheblich an. Die Berücksichtigung besonderer Risikofaktoren bei der Indikationsstellung kann den Eingriff noch sicherer machen.

Abstract

Cataract surgery is a safe procedure with a high patient satisfaction rate. However, pseudophakia changes the physiology of the eye and immediate changes include release of inflammatory cytokines. Deformation of the globe and intraoperative fluctuations of intraocular pressure may induce microlesions and alterations of ocular perfusion. The barrier function between the anterior and the posterior segment is compromised after surgery and the geometry of the intraocular chambers changes. Especially the vitreous body is subject to increased destruction during the years after surgery. The occurrence of pseudophakic cystoid macular edema after cataract surgery is a well known complication. Several studies have described a progression of diabetic retinopathy, especially of diabetic macular edema after cataract surgery. In contrast cataract surgery does not seem to have a significant impact on the progression of age-related macular degeneration. However the risk for retinal detachment is significantly increased in pseudophakia for at least 10 years after surgery. Awareness of special risk factors can make cataract surgery, one of the most effective procedures in medicine, even safer.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Abb. 1
Abb. 2
Abb. 3
Abb. 4

Literatur

  1. Agostini HT, Hansen LL, Feltgen N (2007) Treatment of pseudophakic cystoid macular edema. Ophthalmologe 104:425–426, 428–430

    Article  CAS  PubMed  Google Scholar 

  2. Arne JL (2004) Phakic intraocular lens implantation versus clear lens extraction in highly myopic eyes of 30- to 50-year-old patients. J Cataract Refract Surg 30(10):2092–2096

    Article  PubMed  Google Scholar 

  3. Boberg-Ans G, Henning V, Villumsen J, Cour M (2006) Longterm incidence of rhegmatogenous retinal detachment and survival in a defined population undergoing standardized phacoemulsification surgery. Acta Ophthalmol Scand 84(5):613–618

    Article  PubMed  Google Scholar 

  4. Byer NE (2000) Can rhegmatogenous retinal detachment be prevented? Reflections on the history of „prophylactic“ treatment of retinal detachment. Ophthalmologe 97(10):696–702

    Article  CAS  PubMed  Google Scholar 

  5. Centers for Disease Control and Prevention (1996) Blindness caused by diabetes: Massachusetts, 1987–1994. MMWR Morb Mortal Wkly Rep 45(43):937–941

    Google Scholar 

  6. Cheema RA, Al-Mubarak MM, Amin YM et al (2009) Role of combined cataract surgery and intravitreal bevacizumab injection in preventing progression of diabetic retinopathy: prospective randomized study. J Cataract Refract Surg 35:18–25

    Article  PubMed  Google Scholar 

  7. Chen CH, Liu YC, Wu PC (2009) The combination of intravitreal bevacizumab and phacoemulsification surgery in patients with cataract and coexisting diabetic macular edema. J Ocul Pharmacol Ther 25:83–89

    Article  CAS  PubMed  Google Scholar 

  8. Chew EY, Sperduto RD, Milton RC et al (2009) Risk of advanced age-related macular degeneration after cataract surgery in the age-related eye disease study: AREDS report 25. Ophthalmology 116(2):297–303

    Article  PubMed  Google Scholar 

  9. Coppe AM, Lapucci G (2008) Posterior vitreous detachment and retinal detachment following cataract extraction. Curr Opin Ophthalmol 19:239–242

    Article  PubMed  Google Scholar 

  10. Cugati S, Mitchell P, Rochtchina E et al (2006) Cataract surgery and the 10-year incidence of age-related maculopathy: the Blue Mountains Eye Study. Ophthalmology 113(11):2020–2025

    Article  PubMed  Google Scholar 

  11. Degenring RF, Vey S, Kamppeter B et al (2007) Effect of uncomplicated phacoemulsification on the central retina in diabetic and non-diabetic subjects. Graefes Arch Clin Exp Ophthalmol 245:18–23

    Article  PubMed  Google Scholar 

  12. Donoso LA, Kim D, Frost A et al (2006) The role of inflammation in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 51(2):137–152

    Article  PubMed  Google Scholar 

  13. Dowler JG, Sehmi KS, Hykin PG, Hamilton AM (1999) The natural history of macular edema after cataract surgery in diabetes. Ophthalmology 106(4):663–668

    Article  CAS  PubMed  Google Scholar 

  14. Ederer F, Hiller R, Taylor HR (1981) Senile lens changes and diabetes in two population studies. Am J Ophthalmol 91:381–395

    CAS  PubMed  Google Scholar 

  15. Feltgen N, Weiss C, Wolf S et al (2007) Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment study (SPR study): recruitment list evaluation. Study report no. 2. Graefes Arch Clin Exp Ophthalmol 245(6):803–809

    Article  PubMed  Google Scholar 

  16. Gass JD, Norton EW (1966) Cystoid macular edema and papilledema following cataract extraction. A fluorescein fundoscopic and angiographic study. Arch Ophthalmol 76:646–661

    CAS  PubMed  Google Scholar 

  17. Hayreh SS (1980) Anterior ischemic optic neuropathy. IV. Occurrence after cataract extraction. Arch Ophthalmol 98:1410–1416

    CAS  PubMed  Google Scholar 

  18. Heimann H, Bartz-Schmidt KU, Bornfeld N et al (2007) Scleral buckling versus primary vitrectomy in rhegmatogenous retinal detachment: a prospective randomized multicenter clinical study. Ophthalmology 114(12):2142–2154

    Article  PubMed  Google Scholar 

  19. Hilford D, Hilford M, Mathew A et al (2009) Posterior vitreous detachment following cataract surgery. Eye 23:1388–1392

    Article  CAS  PubMed  Google Scholar 

  20. Ho L, Boekhoorn SS, Liana et al (2008) Cataract surgery and the risk of aging macula disorder: the Rotterdam study. Invest Ophthalmol Vis Sci 49(11):4795–4800

    Article  PubMed  Google Scholar 

  21. Hong T, Mitchell P, Loryn T de et al (2009) Development and progression of diabetic retinopathy 12 months after phacoemulsification cataract surgery. Ophthalmology 116(8):1510–1514

    Article  PubMed  Google Scholar 

  22. Irvine SR (1953) A newly defined vitreous syndrome following cataract surgery. Am J Ophthalmol 36:499–619

    CAS  PubMed  Google Scholar 

  23. Jaffe GJ, Burton TC, Kuhn E et al (1992) Progression of nonproliferative diabetic retinopathy and visual outcome after extracapsular cataract extraction and intraocular lens implantation. Am J Ophthalmol 114:448–456

    CAS  PubMed  Google Scholar 

  24. Kim SJ, Bressler NM (2009) Optical coherence tomography and cataract surgery. Curr Opin Ophthalmol 20:46–51

    Article  CAS  PubMed  Google Scholar 

  25. Kim SJ, Equi R, Bressler NM (2007) Analysis of macular edema after cataract surgery in patients with diabetes using optical coherence tomography. Ophthalmology 114(5):881–889

    Article  PubMed  Google Scholar 

  26. Kim SY, Yang J, Lee YC et al (2008) Effect of a single intraoperative sub-Tenon injection of triamcinolone acetonide on the progression of diabetic retinopathy and visual outcomes after cataract surgery. J Cataract Refract Surg 34:823–826

    Article  PubMed  Google Scholar 

  27. Klein BE, Klein R, Moss SE (1995) Incidence of cataract surgery in the Wisconsin epidemiologic study of diabetic retinopathy. Am J Ophthalmol 119:295–300

    CAS  PubMed  Google Scholar 

  28. Kohnen T, Knorz MC, Neuhann T (2007) Evaluation and quality assurance of refractive surgery procedures by the German Ophthalmological Society and the Professional Association of German Ophthalmologists. Ophthalmologe 104:719–726

    Article  CAS  PubMed  Google Scholar 

  29. Kreis AJ, Aylward GW, Wolfensberger TJ (2007) Prophylaxis for retinal detachment: evidence or eminence based? Retina 27(4):468–472

    Article  PubMed  Google Scholar 

  30. Libre PE (2003) Intraoperative light toxicity: a possible explanation for the association between cataract surgery and age-related macular degeneration. Am J Ophthalmol 136(6):1172–1174

    Article  PubMed  Google Scholar 

  31. Lois N, Wong D (2003) Pseudophakic retinal detachment. Surv Ophthalmol 48(5):467–487

    Article  PubMed  Google Scholar 

  32. Mainster MA, Turner Pl (2009) Blue-blocking IOLs decrease photoreception without providing significant photoprotection. Surv Ophthalmol 55(3):272–289

    Article  PubMed  Google Scholar 

  33. Miyake K, Ibaraki N (2002) Prostaglandins and cystoid macular edema. Surv Ophthalmol [Suppl 1] 47:S203–S218

  34. Neal RE, Bettelheim FA, Lin C et al (2005) Alterations in human vitreous humour following cataract extraction. Exp Eye Res 80:337–347

    Article  CAS  PubMed  Google Scholar 

  35. Neuhann IM, Neuhann TF, Heimann H et al (2008) Retinal detachment after phacoemulsification in high myopia: analysis of 2356 cases. J Cataract Refract Surg 34(10):1644–1657

    Article  PubMed  Google Scholar 

  36. Ohrloff C, Schalnus R, Rothe R et al (1990) Role of the posterior capsule in the aqueous-vitreous barrier in aphakic and pseudophakic eyes. J Cataract Refract Surg 16:198–201

    CAS  PubMed  Google Scholar 

  37. Osterlin S (1977) On the molecular biology of the vitreous in the aphakic eye. Acta Ophthalmol (Copenh) 55:353–361

    Google Scholar 

  38. Osterlin S (1978) Macromolecular composition of the vitreous in the aphakic owl monkey eye. Exp Eye Res 26:77–84

    Article  CAS  PubMed  Google Scholar 

  39. Ramos M, Kruger EF, Lashkari K (2002) Biostatistical analysis of pseudophakic and aphakic retinal detachments. Semin Ophthalmol 17(3–4):206–213

    Google Scholar 

  40. Romero-Aroca P, Fernandez-Ballart J, Almena-Garcia M et al (2006) Nonproliferative diabetic retinopathy and macular edema progression after phacoemulsification: prospective study. J Cataract Refract Surg 32:1438–1444

    Article  PubMed  Google Scholar 

  41. Rossetti L, Autelitano A (2000) Cystoid macular edema following cataract surgery. Curr Opin Ophthalmol 11:65–72

    Article  CAS  PubMed  Google Scholar 

  42. Saidkasimova S, Mitry D, Singh J et al (2009) Retinal detachment in Scotland is associated with affluence. Br J Ophthalmol 93(12):1591–1594

    Article  CAS  PubMed  Google Scholar 

  43. Schalnus RW, Ohrloff C, Magone T (1995) The aqueous humor-vitreous body barrier and the blood-aqueous humor barrier after YAG laser capsulotomy in capsular sac vs ciliary sulcus fixation of the intraocular lens. Ophthalmologe 92:289–292

    CAS  PubMed  Google Scholar 

  44. Shah AS, Chen SH (2010) Cataract surgery and diabetes. Curr Opin Ophthalmol 21(1):4–9

    Article  PubMed  Google Scholar 

  45. Sheu SJ, Ger LP, Ho Wl (2010) Late increased risk of retinal detachment after cataract extraction. Am J Ophthalmol 149:113–119

    Article  PubMed  Google Scholar 

  46. Sutter FK, Menghini M, Barthelmes D et al (2007) Is pseudophakia a risk factor for neovascular age-related macular degeneration? Invest Ophthalmol Vis Sci 48(4):1472–1475

    Article  PubMed  Google Scholar 

  47. Takamura Y, Kubo E, Akagi Y (2009) Analysis of the effect of intravitreal bevacizumab injection on diabetic macular edema after cataract surgery. Ophthalmology 116:1151–1157

    Article  PubMed  Google Scholar 

  48. The Eye Diseases Prevalence Research Group (2004) Prevalence of age related macular degeneration in the United States. Arch Ophthalmol 122(4):564–572

    Article  Google Scholar 

  49. Thompson JT, Glaser BM (1985) Role of lensectomy and posterior capsule in movement of tracers from vitreous to aqueous. Arch Ophthalmol 103:420–421

    CAS  PubMed  Google Scholar 

  50. Tomany SC, Cruickshanks KJ, Klein R et al (2004) Sunlight and the 10-year incidence of age-related maculopathy: the Beaver Dam Eye Study. Arch Ophthalmol 122(5):750–757

    Article  PubMed  Google Scholar 

  51. Tu Kl, Kaye Sb, Sidaras G et al (2007) Effect of intraocular surgery and ketamine on aqueous and serum cytokines. Mol Vis 13:1130–1137

    CAS  PubMed  Google Scholar 

  52. Van der Schaft TL, Mooy CM, Bruijn WC de et al (1994) Increased prevalence of disciform macular degeneration after cataract extraction with implantation of an intraocular lens. Br J Ophthalmol 78(6):441–445

    Article  Google Scholar 

  53. Vinerovsky A, Rath EZ, Rehany U et al (2004) Central retinal artery occlusion after peribulbar anesthesia. J Cataract Refract Surg 30:913–915

    Article  PubMed  Google Scholar 

Download references

Interessenkonflikt

Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to W.A. Herrmann.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Herrmann, W., Heimann, H. & Helbig, H. Kataraktoperation . Ophthalmologe 107, 975–986 (2010). https://doi.org/10.1007/s00347-010-2236-2

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00347-010-2236-2

Schlüsselwörter

Keywords

Navigation