Zusammenfassung
Der Artikel gibt einen Überblick über das Spektrum möglicher Motilitätseinschränkungen und Stellungsanomalien der Augen bei Patienten mit Möbius-Sequenz. Die augenmuskelchirurgischen Behandlungsoptionen werden diskutiert und es wird ein operatives Stufenschema vorgestellt.
Abstract
This article reviews the spectrum of possible motility disorders and ocular misalignment in patients with Möbius sequence. The various options for strabismus surgery are discussed and a stepwise algorithm is presented.
Literatur
Graefe A, Saemisch T (1880) Handbuch der Gesammten Augenheilkunde. Engelman, Leipzig, 6:60
Möbius PJ (1888) Über angeborene doppelseitige Abducens-Facialis-Lähmung. Munch Med Wochschr 35:91–108
Verzijl HT, Zwaag B van der, Cruysberg JR, Padberg GW (2003) Möbius syndrome redefined: a syndrome of rhombencephalic maldevelopment. Neurology 61:327–333
Traboulsi EI (2004) Congenital abnormalities of cranial nerve development:overview, molecular mechanisms, and further evidence of heterogeneity and complexity of syndromes with congenital limitation of eye movements. Trans Am Ophthalmol Soc 102:373–389
Pieh C, Lagrèze WA (2007) Angeborene Fehlinnervationssyndrome. Ophthalmologe 104:1083–1096
Engle EC (2007) Oculomotility disorders arising from disruptions in brainstem motor neuron development. Arch Neurol 64:633–637
Dumars S, Andrews C, Chan WM et al (2008) Magnetic resonance imaging of the endophenotype of a novel familial Möbius-like syndrome. J AAPOS 12:381–389
Cattaneo L, Chierici E, Bianchi B et al (2006) The localization of facial motor impairment in sporadic Möbius syndrome. Neurology 66:1907–1912
Merz M, Wojtowicz S (1967) The Moebius syndrome. Am J Ophthalmol 63:837–840
Taboulsi EI, Maumenee ICH (1986) Extraocular muscle aplasia in Moebius syndrome. J Pediatr Ophthalmol Strabismus 23:120–122
Miller MT, Strömland K (1999) The Möbius Sequence: A Relook. J AAPOS 3:199–208
Momtchilova M, Pelosse B, Rocher F et al (2007) Möbius syndrome: ocular and clinical manifestations. J Fr Ophtalmol 30:177–182
Amaya LG, Walker J, Taylor D (1990) Möbius syndrome: a study and report of 18 cases. Binocul Vis Q 5:119–132
Miller MT, Ray V, Owens P, Chen F (1999) Möbius and Möbius-Like Syndromes (TTV-OFM, OMLH). J Pediatr Ophthalmol Strabismus 26:176–188
Ventura LO, Cruz CB da, Almeida HC de et al (2007) Möbius sequence: long-term strabismus surgical outcome. Arq Bras Oftalmol 70:195–199
Kushner BJ, Biglan AW, Carruthers J et al (1990) Grand rounds #20: A Case of Consecutive Exotropia after a Jensen Procedure for a Lateral Rectus Paralysis Associated with Moebius Syndrome. Binocul Vis Q 5:196–201
Spierer A, Barak A (2000) Strabismus surgery in children with Möbius syndrome. J AAPOS 4:58–59
Abbott RL, Metz HS, Weber AA (1978) Saccadic velocity studies in Moebius syndrome. Ann Ophthalmol 10:619–623
Waterhouse WJ, Enzenauer RW, Martyak AP (1993) Successful strabismus surgery in a child with Moebius syndrome. Ann Ophthalmol 25:292–294
Hicks AM (1943) Congenital paralysis of lateral rotators of eyes with paralysis of muscles of face. Arch Ophthalmol 30:38–42
Stansbury JR (1952) Moebius’s syndrome. Am J Ophthalmol 35:256–261
Sturm V, Menke N, Landau K (2009) Rectus muscle transposition for the treatment of complex ocular motility disorders. Klin Monatsbl Augenheilkd 226:321–327
Kolling GH (2001) Zur Therapie der Abduzensparalyse. Ophthalmologe 98:1169–1175
Sharma P, Gogoi M, Kedar S, Bhola R (2006) Periosteal fixation in third-nerve palsy. J AAPOS 10:324–327
Goldberg RA, Rosenbaum AL, Tong JT (2000) Use of apically based periosteal flaps as globe tethers in severe paretic strabismus. Arch Ophthalmol 118:2431–437
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Sturm, V., Michels, R., Menke, M. et al. Diagnose und Therapie okulomotorischer Defizite bei Patienten mit Möbius-Sequenz. Ophthalmologe 107, 708–712 (2010). https://doi.org/10.1007/s00347-010-2147-2
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DOI: https://doi.org/10.1007/s00347-010-2147-2