Zusammenfassung
Das autosomal-dominant vererbte Brooke-Syndrom ist durch das Auftreten multipler Trichoepitheliome, die als dichtstehende Knötchen im Gesichtsbereich imponieren, gekennzeichnet. Die Therapie besteht bei größeren Tumoren in der Exzision, bei flächenhaft ausgebreiteten Tumoren in der Dermabrasion oder Laserabtragung. Patienten mit Brooke-Syndrom sollten regelmäßig kontrolliert werden, da maligne Hauttumoren auftreten können. Wir stellen hier einen Patienten mit einem Brooke-Syndrom vor und berichten über den Behandlungsverlauf.
Abstract
Brooke’s syndrome is a rare autosomal dominant dermatosis characterized by multiple trichoepitheliomas, which preferentially arise in the face. Therapy consists of excisional surgery of larger tumors and for multiple lesions, dermal abrasion or laser therapy may be considered. Patients with Brooke’s syndrome should be closely followed-up due to the possible development of malignant skin tumours. Here, we present a patient with Brooke’s syndrome and report on the course of treatment.
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Rensch, F., Harder, B., Goebeler, M. et al. Multiple familiäre Trichoepitheliome (Brooke-Syndrom). Ophthalmologe 106, 735–739 (2009). https://doi.org/10.1007/s00347-008-1848-2
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DOI: https://doi.org/10.1007/s00347-008-1848-2