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Fulminanter Verlauf einer orbitalen Mucoracea-Infektion

Fulminant process of an orbital Mucoracea infection

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Zusammenfassung

Die rhinoorbitozerebrale Mukormykose ist eine seltene invasive Pilzinfektion, die unbehandelt tödlich verläuft. Vorgestellt wird der Fall einer immunsupprimierten Patientin, die bei Z. n. allogener Stammzelltransplantation bei chronisch lymphatischer Leukämie eine schwere rhinoorbitozerebrale Mukormykose entwickelte. Aufgrund des fulminanten und möglicherweise tödlichen Verlaufs ist bei entsprechenden klinischen Zeichen auch ohne eines histopathologischen Nachweises eine radikale Entfernung der gesamten nekrotischen Areale in Kombination mit antifungaler Therapie unerlässlich.

Abstract

Rhinoorbitocerebral mucormycosis is a rare invasive fungal infection that is fatal when untreated. We describe an immunosuppressed patient with chronic lymphatic leukaemia who developed a severe rhinoorbitocerebral mucormycosis after allogeneic bone marrow transplantation. Due to the potentially fulminant course and fatal outcome, radical excision of the necrotic area in combination with antifungal therapy is necessary in the presence of suspicious clinical signs of mucormycosis despite a lack of histopathologic confirmation.

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Authors and Affiliations

  1. Department für Augenheilkunde, Universität Tübingen, Schleichstraße 12-16, 72076, Tübingen, Deutschland

    C. Jägle, E. Papageorgiou, U. Schiefer &  H. Jägle

  2. Universitäts-HNO Klinik, Tübingen, Deutschland

    C. Jägle, S. Preyer & H. Löwenheim

Authors
  1. C. Jägle
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  2. E. Papageorgiou
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  3. S. Preyer
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  4. H. Löwenheim
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  5. U. Schiefer
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  6. H. Jägle
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Correspondence to H. Jägle.

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Jägle, C., Papageorgiou, E., Preyer, S. et al. Fulminanter Verlauf einer orbitalen Mucoracea-Infektion. Ophthalmologe 106, 547–550 (2009). https://doi.org/10.1007/s00347-008-1830-z

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  • DOI: https://doi.org/10.1007/s00347-008-1830-z

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