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Okuläre Pulsamplitude als biometrischer Messwert in der Glaukomdiagnostik

Ocular pulse amplitude: a new biometrical parameter for the diagnose of glaucoma?

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Zusammenfassung

Hintergrund

Die dynamische Konturtonometrie (DCT) ermöglicht direkte transkorneale Messungen des Augeninnendrucks und der okulären Pulsamplitude (OPA). Ziel dieser Studie war es, herauszufinden, ob die OPA als biometrischer Messwert Aussagen über verschiedene Glaukomformen erlaubt.

Patienten und Methoden

Es wurden 441 Augen von 222 Patienten in die Studie aufgenommen. Zur Druckmessung dienten die DCT und ein Applanationstonometer nach Goldmann.

Ergebnisse

Die mittlere OPA betrug 3,1±1,4 mmHg. Augen mit okulärer Hypertension (3,6±1,3 mmHg) zeigten signifikant höhere Werte als gesunde Augen (3,1±1,4 mmHg) und solche mit Niederdruckglaukom (2,9±1,4 mmHg). Nach erfolgreicher Trabekulektomie wurden signifikant tiefere Werte (2,4±1,3 mmHg) als bei Gesunden gemessen.

Schlussfolgerung

Die OPA scheint diverse Formen des Glaukoms zu charakterisieren, könnte aber auch direkt von der Höhe des Augendrucks abhängen. Es muss weiter abgeklärt werden, ob sie einen prädiktiven Faktor in der Diagnose und der Verlaufsbeurteilung des Glaukoms darstellt.

Abstract

Background

Dynamic contour tonometry (DCT) enables accurate transcorneal measurements of the intraocular pressure and ocular pulse amplitude (OPA). In this study, we investigated whether this new biometrical parameter can characterize different glaucoma types and serve as a helpful tool in the diagnosis and therapy of the disease.

Patients and methods

A total of 441 eyes of 222 patients were included. Pressure measurements were performed with contour and applanation tonometry.

Results

Mean OPA was 3.1±1.4 mmHg. Eyes with ocular hypertension showed significantly higher OPA values (3.6±1.3 mmHg) than healthy eyes (3.1±1.4 mmHg) and eyes with low-tension glaucoma (2.9±1.4 mmHg). After trabeculectomy, the values were significantly lower (2.4±1.3 mmHg) than in healthy eyes.

Conclusion

The size of the OPA seems to be characteristic for different types of glaucoma and directly dependent on intraocular pressure levels. Further investigation is indicated to clarify its diagnostic usefulness.

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Authors and Affiliations

  1. Augenklinik, Universitätsspital Zürich, Frauenklinikstraße 24, 8091, Zürich, Schweiz

    T. Romppainen

  2. Augenklinik, Kantonsspital Winterthur, Winterthur, Schweiz

    T. Romppainen, C. Kniestedt & J. Stürmer

  3. Horten Zentrum für praxisorientierte Forschung und Wissenstransfer, Zürich, Schweiz

    L.M. Bachmann

Authors
  1. T. Romppainen
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  2. C. Kniestedt
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  3. L.M. Bachmann
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  4. J. Stürmer
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Correspondence to T. Romppainen.

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Romppainen, T., Kniestedt, C., Bachmann, L. et al. Okuläre Pulsamplitude als biometrischer Messwert in der Glaukomdiagnostik. Ophthalmologe 104, 230–235 (2007). https://doi.org/10.1007/s00347-006-1467-8

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  • DOI: https://doi.org/10.1007/s00347-006-1467-8

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