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Transpupillare Thermotherapie bei subfovealer choroidaler Neovaskularisation

Ein 9-Monats-Follow-up

Transpupillary thermotherapy for subfoveal choroidal neovascularization

A 9-month follow-up

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Zusammenfassung

Ziel

Ziel der vorliegenden Arbeit ist es, die Wirksamkeit, Stabilität und Sicherheit der transpupillaren Thermotherapie als Behandlungsmethode der subfovealen okkulten choroidalen Neovaskularisation (CNV) bei der alterskorrelierten Makuladegeneration (AMD) zu untersuchen.

Patienten und Methoden

Die transpupillare Thermotherapie (TTT) wurde an 40 Patienten mit ein- oder beidseitiger vorwiegend okkulter CNV durchgeführt. Mittels eines Infrarotdiodenlasers mit der Wellenlänge 810 nm wurden Laserherde für eine Dauer von 60 s appliziert. Eine komplette ophthalmologische Untersuchung wurde vor sowie 9 Monate nach Behandlung durchgeführt.

Ergebnisse

Nach 9 Monaten stabilisierte sich die Sehschärfe bei 65% (±2 Zeilen). Bei 35% konnte durch die TTT ein weiterer Visusverlust nicht aufgehalten werden. Die Leckage von Flüssigkeit, dargestellt in der Fluoreszeinangiographie, stabilisierte sich bei 67,5% der behandelten Patienten.

Schlussfolgerungen

Die vorliegenden Daten zeigen eine Stabilisierung der Sehschärfe in 65% nach TTT. Verglichen mit dem Spontanverlauf okkulter bzw. vorwiegend okkulter CNV, weisen diese Daten auf einen Benefit für die Patienten nach TTT hin.

Abstract

Purpose

The purpose of this study was to evaluate the efficiency, stability, and safety of transpupillary thermotherapy as a treatment of subfoveal occult choroidal neovascularizations (CNV) in age-related macular degeneration.

Methods

Transpupillary thermotherapy (TTT) was performed in 40 patients with uni- or bilateral predominantly occult CNV. Laser light derived from an infrared diode laser at 810 nm was used to apply spots for a duration of 60 s. A complete ophthalmic examination was performed prior to and 9 months after the treatment.

Results

After 9 months, visual acuity remained stable in 65% (±2 lines). In 35% of the patients TTT could not prevent further visual loss. Retinal leakage, assessed by fluorescein angiography, stabilized in 67.5% of the treated patients.

Conclusions

The present data show stabilization of visual acuity in 65% after TTT. Compared to the natural course of occult and mixed subfoveal CNV, these data give some evidence for patient benefit after TTT.

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Authors and Affiliations

  1. Augenklinik, Universität, Hamburg

    M. Feucht, B. Fuisting & G. Richard

  2. Augenklinik, Universität Hamburg-Eppendorf, Martinistraße 52, 20246 , Hamburg

    M. Feucht

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  1. M. Feucht
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  2. B. Fuisting
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  3. G. Richard
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Correspondence to M. Feucht.

Additional information

Teile des Vortrags wurden auf der 99. Tagung der Deutschen Ophthalmologischen Gesellschaft gehalten.

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Feucht, M., Fuisting, B. & Richard, G. Transpupillare Thermotherapie bei subfovealer choroidaler Neovaskularisation. Ophthalmologe 101, 1105–1110 (2004). https://doi.org/10.1007/s00347-004-1114-1

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  • DOI: https://doi.org/10.1007/s00347-004-1114-1

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