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Phake Intraokularlinsen

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Zusammenfassung

Die optische Qualität nach Korrektur höherer Fehlsichtigkeiten mittels phaker Intraokularlinsen (PIOL) ist im Vergleich zu korneal-ablativen Verfahren potenziell besser, da die normale prolate korneale Asphärizität bei akzeptabler effektiver optischer Zone erhalten bleibt. Verbesserungen des Materials und Designs phaker IOL, der Implantationsinstrumente sowie eine bessere Kenntnis der Interaktion der PIOL mit den umliegenden anatomischen Strukturen führten in den letzten Jahren zu einer gestiegenen Sicherheit und Akzeptanz. Klinische Studien zu PIOL zeigten eine gute Vorhersagbarkeit, Stabilität und Effektivität. Die Sicherheit dieser Implantate über einen längeren Zeitraum (>5 Jahre) hingegen wurde bislang nicht belegt, auch wenn die Implantation PIOL bereits jetzt von vielen Ophthalmochirurgen unter diversen Umständen als das refraktiv-chirurgische Verfahren der Wahl angesehen wird. In dieser Übersicht wird auf die Vor- und Nachteile der verschiedenen aktuellen PIOL-Typen sowie deren Komplikationen eingegangen. Es ist davon auszugehen, dass Verfeinerungen der Bildgebung zu einer genaueren PIOL-Größenbestimmung (besonders in Hinblick auf die ICL) führen werden. Eine recht präzise Vorhersage der effektiven postoperativen Linsenposition mit geringer Abweichung von der Zielrefraktion wäre somit möglich. Die Patienten sollten wissen, dass die Implantation einer phaken Intraokularlinse die Fehlsichtigkeit weitestgehend ausgleicht, aber sowohl die zugrunde liegende Pathologie als auch die Änderungen durch die Operation zu ernsten Komplikationen führen können.

Abstract

Phakic intraocular lenses (PIOLs), which are located closer to the eye’s nodal points than the anterior corneal surface, can provide superior optical quality for higher corrections because of retention of normal prolate corneal asphericity and larger effective optical zones. Improvements in the material and design of phakic intraocular lenses and their insertion devices combined with advances in the understanding of the anatomical and physiological interactions of the PIOLs with intraocular structures, have increased safety and efficacy. Safety of these implants over the long term remains a concern, but in several situations PIOLs are the refractive correction of choice. The purpose of this review is to compare the different types of PIOLs regarding outcome and complications. Improvements in imaging technologies should improve the accuracy of ICL sizing and allow more precise prediction of effective lens position with more accurate power calculation. It is important to inform patients that phakic lens surgery only corrects the refractive aspect, and that the refractive error itself as well as the changes by surgery still has the potential for serious complications.

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Literatur

  1. Abela-Formanek C, Krüger AJ, Dejaco-Ruhswurm I et al. (2001) Gonioscopic changes after implantation of a posterior chamber lens in phakic myopic eyes. J Cataract Refract Surg 27:1919–1925

    CAS  PubMed  Google Scholar 

  2. Aguilar-Valenzuela L, Lleo-Perez A, Alonso-Munoz L et al. (2003) Intraocular pressure in myopic patients after Worst-Fechner anterior chamber phakic intraocular lens implantation. J Refract Surg 19:131–136

    PubMed  Google Scholar 

  3. Aliò JL, Ruiz-Moreno JM, Artola A (1993) Retinal detachment as a potential hazard in surgical correction of severe myopia with phakic anterior chamber lenses. Am J Ophthalmol 115:145–148

    PubMed  Google Scholar 

  4. Aliò JL, de la Hoz F, Pérez-Santonja JJ et al. (1999) Phakic anterior chamber lenses for the correction of myopia: a 7-year cumulative analysis of complications in 263 cases. Ophthalmology 106:458–466

    PubMed  Google Scholar 

  5. Aliò JL, de la Hoz F, Ruiz-Moreno JM, Salem TF (2000) Cataract surgery in highly myopic eyes corrected by phakic anterior chamber angle-supported lenses (1). J Cataract Refract Surg 26:1303–1311

    PubMed  Google Scholar 

  6. Aliò JL, Mulet ME, Shalaby AM (2002) Artisan phakic iris claw intraocular lens for high primary and secondary hyperopia. J Refract Surg 18:697–707

    PubMed  Google Scholar 

  7. Aliò JL, Kelman C (2003) The Duet-Kelman lens: a new exchangeable angle-supported phakic intraocular lens. J Refract Surg 19:488–495

    PubMed  Google Scholar 

  8. Allemann N, Chamon W, Tanaka HM et al. (2000) Myopic angle-supported intraocular lenses: two-year follow-up. Ophthalmology 107:1549–1554

    CAS  PubMed  Google Scholar 

  9. Ardjomand N, Kolli H, Vidic B et al. (2002) Pupillary block after phakic anterior chamber intraocular lens implantation. J Cataract Refract Surg 28:1080–1081

    PubMed  Google Scholar 

  10. Arne JL, Lesueur LC, Hulin HH (2003) Photorefractive keratectomy or laser in situ keratomileusis for residual refractive error after phakic intraocular lens implantation. J Cataract Refract Surg 29:1167–1173

    PubMed  Google Scholar 

  11. Baikoff G, Arne JL, Bokobza Y et al. (1998) Angle-fixated anterior chamber phakic intraocular lens for myopia of −7 to −19 diopters. J Refract Surg 14:282–293

    CAS  PubMed  Google Scholar 

  12. BenEzra D, Cohen E, Karshai I (2000) Phakic posterior chamber intraocular lens for the correction of anisometropia and treatment of amblyopia. Am J Ophthalmol 130:292–296

    CAS  PubMed  Google Scholar 

  13. Brandt JD, Mockovak, Chayet A (2001) Pigmentary dispersion syndrome induced by a posterior chamber phakic refractive lens. Am J Ophthalmol 131:260–263

    CAS  PubMed  Google Scholar 

  14. Brauweiler PH, Wehler T, Busin M (1999) High incidence of cataract formation after implantation of a silicone posterior chamber lens in phakic, highly myopic eyes. Ophthalmology 106:1651–1655

    CAS  PubMed  Google Scholar 

  15. Brunette I, Bueno JM, Harissi-Dagher M et al. (2003) Optical quality of the eye with the Artisan phakic lens for the correction of high myopia. Optom Vis Sci 80:167–174

    PubMed  Google Scholar 

  16. Budo C, Hessloehl JC, Izak M et al. (2000) Multicenter study of the Artisan phakic intraocular lens. J Cataract Refract Surg 26:1163–1171

    Article  CAS  PubMed  Google Scholar 

  17. Bylsma SS; Zalta AH, Foley E, Osher RH (2002) Phakic posterior chamber lens pupillary block. J Cataract Refract Surg 28:2222–2228

    PubMed  Google Scholar 

  18. Chiou AG, Bovet J, de Courten C (2001) Pseudophakic ametropia managed with phakic posterior chamber intraocular lens. J Cataract Refract Surg 27:1516–1518

    CAS  PubMed  Google Scholar 

  19. Colin J, Robinet A, Cochener B (1999) Retinal detachment after clear lens extraction for high myopia: seven-year follow-up. Ophthalmology 106:2281–2284

    CAS  PubMed  Google Scholar 

  20. Comaish IF, Lawless MA (2002) Phakic intraocular lenses. Curr Opin Ophthalmol 13:7–13

    PubMed  Google Scholar 

  21. Davidorf JM, Zaldivar R, Oscherow S (1998) Posterior chamber phakic intraocular lens for hyperopia of +4 to +11 diopters. J Refract Surg 14:306–311

    CAS  PubMed  Google Scholar 

  22. de Souza RF, Forseto A, Nose R et al. (2001) Anterior chamber intraocular lens for high myopia: five year results.J Cataract Refract Surg 27:1248–1253

    PubMed  Google Scholar 

  23. de Souza RF, Allemann N, Forseto A et al. (2003) Ultrasound biomicroscopy and Scheimpflug photography of angle-supported phakic intraocular lens for high myopia. J Cataract Refract Surg 29:1159–1166

    PubMed  Google Scholar 

  24. Dejaco-Ruhswurm I, Scholz U, Pieh S et al. (2002) Long-term endothelial changes in phakic eyes with posterior chamber intraocular lenses. J Cataract Refract Surg 28:1589–1593

    PubMed  Google Scholar 

  25. Dick HB, Krummenauer F, Schwenn O et al. (1999) Objective and subjective evaluation of photic phenomena after monofocal and multifocal intraocular lens implantation. Ophthalmology 106:1878–1886

    CAS  PubMed  Google Scholar 

  26. Dick HB, Augustin AJ, Pfeiffer N (2000) Osmolality of viscoelastic substances. J Cataract Refract Surg 26:1242–1246

    CAS  PubMed  Google Scholar 

  27. Dick HB, Schwenn O (2000) Viscoelastics in ophthalmic surgery. Springer, Berlin Heidelberg New York Tokyo

  28. Dick HB, Gross S, Tehrani M et al. (2002) Refractive lens exchange with an Array multifocal intraocular lens. J Refract Surg 18:509–518

    PubMed  Google Scholar 

  29. Dick HB, Aliò J, Bianchetti M et al. (2003) Toric phakic intraocular lens: European multicenter study. Ophthalmology 110:150–162

    Article  PubMed  Google Scholar 

  30. El Danasoury MA, El Maghraby A, Gamali TO (2002) Comparison of iris-fixed Artisan lens implantation with excimer laser in situ keratomileusis in correcting myopia between −9.00 and −19.50 diopters: a randomized study. Ophthalmology 109:955–964

    PubMed  Google Scholar 

  31. Fink AM, Gore C, Rosen E (1999) Cataract development after implantation of the Staar Collamer posterior chamber phakic lens. J Cataract Refract 25:278–282

    CAS  Google Scholar 

  32. García-Feijoó J, Alfaro IJ, Cuiña-Sardiña R et al. (2003) Ultrasound biomicroscopy examination of posterior chamber phakic intraocular lens position. Ophthalmology 110:163–172

    PubMed  Google Scholar 

  33. García-Feijoó J, Hernández-Matamoros JL, Méndez-Hernández C et al. (2003) High-frequency ultrasound biomicroscopy of silicone posterior chamber phakic intraocular lens for hyperopia. J Cataract Refract Surg 29:1940–1946

    PubMed  Google Scholar 

  34. Gonvers M, Bornet C, Othenin-Girard P (2003) Implantable contact lens for moderate to high myopia: relationship of vaulting to cataract formation. J Cataract Refract Surg 29:918–924

    PubMed  Google Scholar 

  35. Guell JL, Vazquez M, Gris O (2001) Adjustable refractive surgery: 6-mm Artisan lens plus laser in situ keratomileusis for the correction of high myopia. Ophthalmology 108:945–952

    CAS  PubMed  Google Scholar 

  36. Guell JL, Vazquez M, Malecaze F et al. (2003) Artisan toric phakic intraocular lens for the correction of high astigmatism. Am J Ophthalmol 136:442–447

    PubMed  Google Scholar 

  37. Hoffer KJ (2001) Pigment vacuum iridectomy for phakic refractive lens implantation. J Cataract Refract Surg 27:1166–1168

    CAS  PubMed  Google Scholar 

  38. Hoffer K (2003) Ultrasound axial length measurement in biphakic eyes. J Cataract Refract Surg 29:961–965

    PubMed  Google Scholar 

  39. Hoyos JE, Dementiev DD, Cigales M et al. (2002) Phakic refractive lens experience in Spain. J Cataract Refract Surg 28:1939–1946

    PubMed  Google Scholar 

  40. ICL in Treatment of Myopia Study Group (2003) Postoperative inflammation after implantation of the implantable contact lens. Ophthalmology 110:2335–2341

    PubMed  Google Scholar 

  41. Jiménez-Alfaro I, Benítez del Castillo JM, García-Feijoó J et al. (2000) Safety of posterior chamber phakic intraocular lenses for the correction of high myopia: anterior segment changes after posterior chamber phakic intraocular lens implantation. Ophthalmology 108:90–99

    Article  Google Scholar 

  42. Jiménez-Alfaro I, Gómez-Tellería G, Bueno JL, Puy P (2001) Contrast sensitivity after posterior chamber phakic intraocular lens implantation for high myopia. J Refract Surg 17:641–645

    PubMed  Google Scholar 

  43. Jiménez-Alfaro I, Garcia-Feijoo J, Pérez-Santonja JJ, Cuina R (2001) Ultrasound biomicroscopy of ZSAL-4 anterior chamber phakic intraocular lens for high myopia. J Cataract Refract Surg 27:1567–1573

    PubMed  Google Scholar 

  44. Kaya V, Kevser MA, Yilmaz OF (1999) Phakic posterior chamber plate intraocular lenses for high myopia. J Refract Surg 15:580–585

    CAS  PubMed  Google Scholar 

  45. Keuch RJ, Bleckmann H (2002) Pupil diameter changes and reaction after posterior chamber phakic intraocular lens implantation. J Cataract Refract Surg 28:2170–2172

    PubMed  Google Scholar 

  46. Kim DY, Reinstein DZ, Silverman RH et al. (1998) Very high frequency ultrasound analysis of a new phakic posterior chamber intraocular lens in situ. Am J Ophthalmol 125:725–729

    CAS  PubMed  Google Scholar 

  47. Kodjikian L, Gain P, Donate D et al. (2002) Malignant glaucoma induced by a phakic posterior chamber intraocular lens for myopia. J Cataract Refract Surg 28:2217–2221

    PubMed  Google Scholar 

  48. Kohnen T, Baumeister M, Magdowski G (2000). Scanning electron microscopic characteristics of phakic intraocular lenses. Ophthalmology 107:934–939

    CAS  PubMed  Google Scholar 

  49. Kwok AK, Young AL, Bhende P, Lam DS (1999) Retinal detachment in phakic eyes with anterior chamber intraocular lenses to correct severe myopia. Am J Ophthalmol 128:395–396

    CAS  PubMed  Google Scholar 

  50. Landesz M, Worst JG, van Rij G (2000) Long-term results of correction of high myopia with an iris claw phakic intraocular lens. J Refract Surg 16:310–316

    CAS  PubMed  Google Scholar 

  51. Landesz M, van Rij G, Luyten G (2001) Iris-claw phakic intraocular lens for high myopia. J Refract Surg 17:634–640

    CAS  PubMed  Google Scholar 

  52. Leccisotti A, Fields SV (2003) Angle-supported intraocular lenses in eyes with keratoconus and myopia. J Cataract Refract Surg 29:1530–1536

    PubMed  Google Scholar 

  53. Lesueur LC, Arne JL (2002) Phakic intraocular lens to correct high myopic amblypia in children. J Refract Surg 18:519–523

    PubMed  Google Scholar 

  54. Loewenstein A, Goldstein M, Lazar M (2002) Retinal pathology occurring after excimer laser surgery or phakic intraocular lens implantation: evaluation of possible relationship. Surv Ophthalmol 47:125–135

    PubMed  Google Scholar 

  55. Maloney RK, Nguyen LH, John ME (2002) Artisan phakic intraocular lens for myopia: short-term results of a prospective, multicenter study. Ophthalmology 109:1631–1641

    PubMed  Google Scholar 

  56. Marinho A, Pinto MC, Vaz F (2000) Phakic intraocular lenses: which to choose. Curr Opin Ophthalmol 11:280–288

    CAS  PubMed  Google Scholar 

  57. Maroccos R, Vaz F, Marinho A et al. (2001) Glare and halos after „phakic IOL“. Surgery for the correction of high myopia. Ophthalmologe 98:1055–1059

    CAS  PubMed  Google Scholar 

  58. Menezo JL, Cisneros A, Hueso JR, Harto M (1995) Long-term results of surgical treatment of high myopia with Worst-Fechner intraocular lenses. J Cataract Refract Surg 21:93–98

    CAS  PubMed  Google Scholar 

  59. Menezo JL, Cisneros AL, Rodriguez-Salvador V (1997) Removal of age-related cataract and iris claw phakic intraocular lens. J Refract Surg 13:589–590

    CAS  PubMed  Google Scholar 

  60. Menezo JL, Cisneros AL, Rodriguez-Salvador V (1998) Endothelial study of iris-claw phakic lens: four year follow-up. J Cataract Refract Surg 24:1039–1049

    CAS  PubMed  Google Scholar 

  61. Mimouni F, Colin J, Koffi V, Bonnet P (1991) Damage to the corneal endothelium from anterior chamber intraocular lenses in phakic myopic eyes. Refract Corneal Surg 7:277–281

    CAS  PubMed  Google Scholar 

  62. Munoz G, Montes-Mico R, Belda JI, Aliò JL (2003) Cataract after minor trauma in a young patient with an iris-fixated intraocular lens for high myopia. Am J Ophthalmol 135:890–891

    PubMed  Google Scholar 

  63. O’Brien TP, Awwad ST (2002) Phakic intraocular lenses and refractive lensectomy for myopia. Curr Opin Ophthalmol 13:264–270

    PubMed  Google Scholar 

  64. Pérez-Santonja JJ, Iradier MT, Benitez del Castillo JM et al. (1996) Chronic subclinical inflammation in phakic eyes with intraocular lenses to correct myopia. J Cataract Refract Surg 22:183–187

    PubMed  Google Scholar 

  65. Pérez-Santonja JJ, Iradier MT, Sanz-Iglesias L et al. (1996) Endothelial changes in phakic eyes with anterior chamber intraocular lenses to correct high myopia. J Cataract Refract Surg 22:1017–1022

    PubMed  Google Scholar 

  66. Pérez-Santonja JJ, Bueno JL, Zato MA (1997) Surgical correction of high myopia in phakic eyes with Worst-Fechner myopia intraocular lenses. J Refract Surg 13:268–281

    PubMed  Google Scholar 

  67. Pérez-Santonja JJ, Aliò JL, Jimenez-Alfaro I, Zato MA (2000) Surgical correction of severe myopia with an angle-supported phakic intraocular lens. J Cataract Refract Surg 26:1288–1302

    PubMed  Google Scholar 

  68. Pesando PM, Ghiringhello MP, Tagliavacche P (1999) Posterior chamber collamer phakic intraocular lens for myopia and hyperopia. J Refract Surg 15:415–423

    CAS  PubMed  Google Scholar 

  69. Pop M, Mansour M, Payette Y (1999) Ultrasound biomicroscopy of the iris-claw phakic intraocular lens for high myopia. J Refract Surg 15:632–635

    CAS  PubMed  Google Scholar 

  70. Preussner PR, Wahl J, Lahdo H et al. (2002) Ray tracing for intraocular lens calculation. J Cataract Refract Surg 28:1412–1419

    Article  Google Scholar 

  71. Rosen E, Gore C (1998) Staar Collamer posterior chamber phakic intraocular lens to correct myopia and hyperopia. J Cataract Refract Surg 24:596–606

    CAS  PubMed  Google Scholar 

  72. Ruiz-Moreno JM, Aliò JL, Pérez-Santonja JJ, de la Hoz F (1999) Retinal detachment in phakic eyes with anterior chamber intraocular lenses to correct severe myopia. Am J Ophthalmol 3:270–275

    Article  Google Scholar 

  73. Ruiz-Moreno JM, Aliò JL (2003) Incidence of retinal disease following refractive surgery in 9,239 eyes. J Refract Surg 19:534–547

    PubMed  Google Scholar 

  74. Sanchez-Galeana CA, Smith RJ, Rodriguez X et al. (2001) Laser in situ keratomileusis and photorefractive keratectomy for residual refractive error after phakic intraocular lens implantation. J Refract Surg 17:299–304

    CAS  PubMed  Google Scholar 

  75. Sanchez-Galeana CA, Zadok D, Montes M et al. (2002) Refractory intraocular pressure increase after phakic posterior chamber intraocular lens implantation. Am J Ophthalmol 134:121–123

    PubMed  Google Scholar 

  76. Sanchez-Galeana CA, Smith RJ, Sanders DR et al. (2003) Lens opacities after posterior chamber phakic intraocular lens implantation. Ophthalmology 110:781–785

    PubMed  Google Scholar 

  77. Sanders DR, Vukich JA, ICL in Treatment of Myopia (ITM) Study Group (2002) Incidence of lens opacities and clinically significant cataracts with the implantable contact lens: comparison of two lens designs. J Refract Surg 18:673–682

    PubMed  Google Scholar 

  78. Sanders DR, Vukich JA, Doney K, Gaston M (2003) Implantable Contact Lens in treatment of Myopia Study Group. U.S. Food and Drug Administration clinical trial of the Implantable Contact Lens for moderate to high myopia. Ophthalmology 110:255–266

    PubMed  Google Scholar 

  79. Sanders DR (2003) Actual and theoretical risks for visual loss following use of the implantable contact lens for moderate to high myopia. J Cataract Refract Surg 29:1323–1332

    PubMed  Google Scholar 

  80. Saragoussi JJ, Puech M, Assouline M et al. (1997) Ultrasound biomicroscopy of Baikoff anterior chamber phakic intraocular lenses. J Refract Surg 13:135–141

    CAS  PubMed  Google Scholar 

  81. Saxena R, Landesz M, Noordzij B, Luyten GP (2003) Three-year follow-up of the Artisan phakic intraocular lens for hypermetropia. Ophthalmology 110:1391–1395

    PubMed  Google Scholar 

  82. Saxena R, van Minderhout HM, Luyten GP (2003) Anterior chamber iris-fixated phakic intraocular lens for anisometropic amblyopia. J Cataract Refract Surg 29:835–838

    PubMed  Google Scholar 

  83. Tehrani M, Dick HB (2002) Korrektur eines höhergradigen Astigmatismus nach Keratoplastik durch Implantation einer phaken torischen Iris-Klauen-Linse. Klin Monatsbl Augenheilkd 219:159–163

    PubMed  Google Scholar 

  84. Tehrani M, Dick HB, Schwenn O et al. (2003) Postoperative astigmatism and rotational stability after Artisan toric phakic intraocular lens implantation. J Cataract Refract Surg 29:1761–1766

    PubMed  Google Scholar 

  85. Urrets-Zavalia A (1963) Fixed, dilated pupil, iris atrophy and secondary glaucoma: a distinct clinical entity following penetrating keratoplasty in keratoconus. Am J Ophthalmol 56:257–265

    PubMed  Google Scholar 

  86. Uusitalo RJ, Aine E, Sen NH, Laatikainen L (2002) Implantable contact lens for high myopia. J Cataract Refract Surg 28:29–36

    PubMed  Google Scholar 

  87. Yoon H, Macaluso DC, Moshirfar M, Lundergan M (2002) Traumatic dislocation of an Ophtec Artisan phakic intraocular lens. J Refract Surg 18:481–483

    PubMed  Google Scholar 

  88. Zaldivar R, Oscherow S, Ricur G (2000) The STAAR posterior chamber phakic intraocular lens. Int Ophthalmol Clin 40:237–244

    CAS  PubMed  Google Scholar 

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Dick, H.B., Tehrani, M. Phake Intraokularlinsen. Ophthalmologe 101, 232–245 (2004). https://doi.org/10.1007/s00347-004-0990-8

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