Abstract
Trospium chloride (TCL), a quaternary ammonium derivative of nortropanol, has been evaluated in a number of clinical and pharmacological studies. Selected pharmacological and clinical pharmacokinetic data are discussed as providing a basis for a better interpretation and understanding of the clinical trial results. An overview of the results of 20 clinical trials and post-marketing surveillance studies including more than 10 000 patients is presented.
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Höfner, K., Oelke, M., Machtens, S. et al. Trospium chloride – an effective drug in the treatment of overactive bladder and detrusor hyperreflexia. World J Urol 19, 336–343 (2001). https://doi.org/10.1007/s003450100225
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DOI: https://doi.org/10.1007/s003450100225