Skip to main content
Log in

Thulium:YAG laser: a good compromise between holmium:YAG and thulium fiber laser for endoscopic lithotripsy? A narrative review

  • Original Article
  • Published:
World Journal of Urology Aims and scope Submit manuscript

Abstract

Purpose

To provide a technological description of the new pulsed solid-state Thulium:YAG laser (Tm:YAG). In addition, current available literature on Tm:YAG lithotripsy is also reviewed.

Materials and methods

Medline, Scopus, Embase, and Web of Science databases were used to search for Tm:YAG operating mode articles.

Results

Tm:YAG technology works with a laser cavity with thulium-doped YAG crystal, pumped by laser diodes. Laser beam operates at 2013 nm, with an adjustable peak power (≥ 1000 W) and the minimal fiber laser diameter is of 200 µm. It has an intermediate water absorption coefficient and peak power-pulse duration. Various pulse modulations are proposed, aiming to minimize stone retropulsion. Multiple comparative in vitro studies suggest that Tm:YAG’s ability to fragment stones is similar to the one of the Ho:YAG laser; on the contrary, its ability to dust all stone types is similar to the one of the TFL, with a low retropulsion. A single in vivo study assessed Tm:YAG lithotripsy feasibility.

Conclusions

The new pulsed solid-state thulium:YAG laser could represent a safe and effective compromise between Ho:YAG laser and TFL for endoscopic lithotripsy, either in retrograde intra-renal surgeries or in percutaneous nephrolithotomy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

Data availability

Data is available on request to the corresponding authors.

References

  1. Scales CD, Smith AC, Hanley JM, Saigal CS, Urologic Diseases in America Project (2012) Prevalence of kidney stones in the United States. Eur Urol 62(1):160–165

    Article  PubMed  PubMed Central  Google Scholar 

  2. Raheem OA, Khandwala YS, Sur RL, Ghani KR, Denstedt JD (2017) Burden of urolithiasis: trends in prevalence, treatments, and costs. Eur Urol Focus 3(1):18–26

    Article  PubMed  Google Scholar 

  3. Stamatelou K, Goldfarb DS (2023) Epidemiology of kidney stones. Healthc Basel Switz 11(3):424

    Google Scholar 

  4. Türk C, Petřík A, Sarica K, Seitz C, Skolarikos A, Straub M et al (2016) EAU Guidelines on Interventional Treatment for Urolithiasis. Eur Urol 69(3):475–482

    Article  PubMed  Google Scholar 

  5. Johnson DE, Cromeens DM, Price RE (1992) Use of the holmium:YAG laser in urology. Lasers Surg Med 12(4):353–363

    Article  CAS  PubMed  Google Scholar 

  6. Urofrance | Recommandations de bonne pratique pour la prise en charge des calculs et de la lithiase urinaires: diagnostic, traitement, suivi et prévention secondaire—Argumentaire—Urofrance [Internet]. 2022 [cité 17 Nov 2022]. Disponible sur: https://www.urofrance.org/recommandation/recommandations-de-bonne-pratique-pour-la-prise-en-charge-des-calculs-et-de-la-lithiase-urinaires-diagnostic-traitement-suivi-et-prevention-secondaire-argumentaire/

  7. Keller EX, De Coninck V, Doizi S, Daudon M, Traxer O (2020) What is the exact definition of stone dust? An in vitro evaluation. World J Urol 8:1

    Google Scholar 

  8. Keller EX, De Coninck V, Doizi S, Daudon M, Traxer O (2021) Thulium fiber laser: ready to dust all urinary stone composition types? World J Urol 39(6):1693–1698

    Article  CAS  PubMed  Google Scholar 

  9. Keller EX, de Coninck V, Audouin M, Doizi S, Bazin D, Daudon M et al (2019) Fragments and dust after Holmium laser lithotripsy with or without « Moses technology »: How are they different? J Biophotonics avr 12(4):e201800227

    Article  Google Scholar 

  10. Traxer O, Keller EX (2020) Thulium fiber laser: the new player for kidney stone treatment? A comparison with Holmium:YAG laser. World J Urol 38(8):1883–1894

    Article  CAS  PubMed  Google Scholar 

  11. Panthier F, Doizi S, Corrales M, Traxer O (2021) Pulsed lasers and endocorporeal laser lithotripsy. Prog En Urol 31(8–9):451–457

    Article  CAS  Google Scholar 

  12. Petzold R, Miernik A, Suarez-Ibarrola R (2021) In vitro dusting performance of a new solid state thulium laser compared to holmium laser lithotripsy. J Endourol 35(2):221–225

    Article  PubMed  Google Scholar 

  13. Kraft L, Yilmaz M, Petzold R, Gratzke C, Suarez-Ibarrola R, Miernik A (2022) Dusting efficiency of a novel pulsed thulium: yttrium aluminum garnet laser vs. a thulium fiber laser. J Endourol 36(2):259–265

    Article  PubMed  Google Scholar 

  14. Petzold R, Suarez-Ibarrola R, Miernik A (2021) Temperature assessment of a novel pulsed thulium solid-state laser compared with a Holmium:Yttrium-Aluminum-Garnet Laser. J Endourol 35(6):853–859

    Article  PubMed  Google Scholar 

  15. Manuel d’utilisation Dornier Thulio. Dornier (2022)

  16. Petzold R, Suarez-Ibarrola R, Miernik A (2021) Gas bubble anatomy during laser lithotripsy: an experimental in vitro study of a pulsed solid-state Tm:YAG and Ho:YAG Device. J Endourol 35(7):1051–1057

    Article  PubMed  Google Scholar 

  17. Kraft L, Petzold R, Suarez-Ibarrola R, Miernik A (2022) In vitro fragmentation performance of a novel, pulsed Thulium solid-state laser compared to a Thulium fibre laser and standard Ho:YAG laser. Lasers Med Sci 37(3):2071–2078

    Article  PubMed  Google Scholar 

  18. Kwok JL, Ventimiglia E, De Coninck V, Corrales M, Sierra A, Panthier F et al (2023) Pulsed thulium:YAG laser-ready to dust all urinary stone composition types? Results from a PEARLS analysis. World J Urol 2023:1

    Google Scholar 

  19. Petzold R, Miernik A, Suarez-Ibarrola R (2021) Retropulsion force in laser lithotripsy—an in vitro study comparing a Holmium device to a novel pulsed solid-state Thulium laser. World J Urol 39(9):3651–3656

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  20. Panthier F, Solano C, Chicaud M, Kutchukian S, Candela L, Doizi S et al (2023) Initial clinical experience with the pulsed solid-state thulium YAG laser from Dornier during RIRS: first 25 cases. World J Urol 41(8):2119–2125

    Article  CAS  PubMed  Google Scholar 

  21. Ventimiglia E, Villa L, Doizi S, Briganti A, Proietti S, Giusti G et al (2021) Laser lithotripsy: the importance of peak power and pulse modulation. Eur Urol Focus 7(1):22–25

    Article  PubMed  Google Scholar 

  22. Traxer O, Corrales M (2021) Managing urolithiasis with thulium fiber laser: updated real-life results—a systematic review. J Clin Med 10(15):3390

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Blackmon RL, Irby PB, Fried NM (2011) Comparison of holmium:YAG and thulium fiber laser lithotripsy: ablation thresholds, ablation rates, and retropulsion effects. J Biomed Opt 16(7):071403

    Article  PubMed  Google Scholar 

  24. Ventimiglia E, Doizi S, Kovalenko A, Andreeva V, Traxer O (2020) Effect of temporal pulse shape on urinary stone phantom retropulsion rate and ablation efficiency using holmium:YAG and super-pulse thulium fibre lasers. BJU Int 126(1):159–167

    Article  CAS  PubMed  Google Scholar 

  25. Wollin DA, Ackerman A, Yang C, Chen T, Simmons WN, Preminger GM et al (2017) Variable pulse duration from a new Holmium:YAG Laser: the effect on stone comminution, fiber tip degradation, and retropulsion in a dusting model. Urology 103:47–51

    Article  PubMed  Google Scholar 

  26. Æsøy MS, Juliebø-Jones P, Beisland C, Ulvik Ø (2022) Temperature profiles during ureteroscopy with thulium fiber laser and holmium:YAG laser: findings from a pre-clinical study. Scand J Urol 56(4):313–319

    Article  PubMed  Google Scholar 

  27. Panthier F, Pauchard F, Traxer O (2023) Retrograde intra renal surgery and safety: pressure and temperature. A systematic review. Curr Opin Urol 33(4):308–317

    Article  PubMed  Google Scholar 

  28. Aldoukhi AH, Black KM, Hall TL, Roberts WW, Ghani KR (2020) Frequency threshold for ablation during holmium laser lithotripsy: How high can you go? J Endourol 34(10):1075–1081

    Article  PubMed  Google Scholar 

  29. Aldoukhi AH, Hall TL, Ghani KR, Roberts WW (2021) Strike rate: analysis of laser fiber to stone distance during different modes of laser lithotripsy. J Endourol 35(3):355–359

    Article  PubMed  Google Scholar 

  30. Panthier F, Doizi S, Gorny C, Berthe L, Traxer O (2020) Impact of laser fiber diameter and irrigation fluids on induced bubble stream dynamics with superpulsed thulium fiber laser: an in vitro study. J Endourol 2020:1

    Google Scholar 

  31. Panthier F, Doizi S, Lapouge P, Chaussain C, Kogane N, Berthe L et al (2020) Comparison of the ablation rates, fissures and fragments produced with 150 µm and 272 µm laser fibers with superpulsed thulium fiber laser: an in vitro study. World J Urol 2020:1

    Google Scholar 

  32. Nazif OA, Teichman JMH, Glickman RD, Welch AJ (2004) Review of laser fibers: a practical guide for urologists. J Endourol 18(9):818–829

    Article  PubMed  Google Scholar 

  33. Haddad M, Emiliani E, Rouchausse Y, Coste F, Doizi S, Berthe L et al (2017) Impact of the curve diameter and laser settings on laser fiber fracture. J Endourol 31(9):918–921

    Article  PubMed  Google Scholar 

  34. Laser JC (2020) Lithotripsy fundamentals: from the physics to optimal fragmentation. Open Access J Urol Nephrol 5(3):1–10

    Article  Google Scholar 

  35. Ulvik Ø, Æsøy MS, Juliebø-Jones P, Gjengstø P, Beisland C (2022) Thulium fibre laser versus Holmium:YAG for ureteroscopic lithotripsy: outcomes from a prospective randomised clinical trial. Eur Urol (Internet). 14 mars 2022 [cité 16 mars 2022]. Disponible sur: https://www.europeanurology.com/article/S0302-2838(22)01669-4/fulltext

Download references

Funding

No funding to declare for this study.

Author information

Authors and Affiliations

Authors

Contributions

FP: project development, data collection and management, data analysis, manuscript writing et editing. MC: project development, data collection and management, manuscript writing et editing. MC: manuscript writing et editing. SK: data collection and management. CS: manuscript writing et editing. LC: manuscript writing et editing. SD: project development, manuscript writing et editing. OT: project development, data analysis, manuscript writing et editing.

Corresponding author

Correspondence to Frédéric Panthier.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest but: Frédéric Panthier has declared as consultant for Dornier. Olivier Traxer has declared as consultant for Karl Storz, Coloplast, IPG photonics, Ambu, Quanta System and Rocamed. Steeve Doizi has declared as consultant for Boston Scientific Corporation and Coloplast.

Informed consent

This article does not contain any studies with human participants or animals performed by any of the authors. Human stone samples were used in this study, with the informed consent of each patient.

Research involving human participants or animals

This article does not contain any studies with human participants or animals performed by any of the authors.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chicaud, M., Corrales, M., Kutchukian, S. et al. Thulium:YAG laser: a good compromise between holmium:YAG and thulium fiber laser for endoscopic lithotripsy? A narrative review. World J Urol 41, 3437–3447 (2023). https://doi.org/10.1007/s00345-023-04679-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00345-023-04679-3

Keywords

Navigation