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Patient compliance for metabolic evaluation and medical treatment (CoMET) in calcium-oxalate stone patients: prospective study by EULIS eCORE study group

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Abstract

Purpose

In this study, we aimed to identify the compliance rates of calcium-oxalate stone patients for metabolic evaluation, diet and medical treatment and also determine the factors that are associated with poor compliance rates.

Methods

This study was conducted by the EULIS eCORE working group prospectively. In the initial visit, demographic and stone-related characteristics were recorded. Patients were suggested metabolic evaluation, dietary advices and medical treatment. Follow-up visit was performed after 3 months and compliance rates were recorded. Logistic regression analysis was performed to determine factors associated with poor compliance to metabolic evaluation, diet and medical treatment.

Results

Data of 346 patients from nine centers were analyzed. Compliance rates were 71.7%, 65.3%, and 63.7% for metabolic evaluation, diet, and medical treatment, respectively. In multivariate analysis, level of education (p = 0.003), history of emergency department visit (p = 0.04), number of stone surgeries (p = 0.03), patient care in dedicated stone clinic (p = 0.03), and history of shock wave lithotripsy (p = 0.005) were detected as independent predictors of compliance to metabolic analysis. Level of education (p < 0.001) and history of emergency department visit (p = 0.01) were detected as independent predictors of patient compliance to diet. Number of stone episodes (p = 0.03), family history of stones (p = 0.02), and polypharmacy (p < 0.001) were detected as independent predictors of patient compliance to medical treatment.

Conclusions

Patient compliance to metabolic evaluation, diet, and medical therapy is important for successful management of urolithiasis. Dietary advices and medications should be personalized by taking in to account the factors associated with poor compliance.

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Data availability

Data available on request from the authors.

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Acknowledgements

The study was supported by the EAU Foundation for Urological Research (EAU RF).

Funding

The authors declare that they have no relevant financial.

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Authors and Affiliations

  1. Department of Urology, Ankara University School of Medicine, Sancak Mahallesi Turan Güneş Bulvarı, 39/23, Çankaya, 06550, Ankara, Turkey

    Mehmet İlker Gökce & Muhammed Arif İbiş

  2. Department of Urology, NEÜ Meram Medicine Faculty, Konya, Turkey

    Selçuk Güven & Giray Sönmez

  3. Department of Urology and Nephrology, Military Medical Academy, Sofia, Bulgaria

    Kremena Petkova

  4. Department of Urology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

    Tzevat Tefik

  5. Department of Urology, Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia

    Nariman Gadzhiev

  6. Department of Urology, School of Medicine, Koc University, Istanbul, Turkey

    Murat Can Kiremit

  7. Department of Urology, Prof. Dr. Cemil Tascıoglu City Hospital Training and Research Hospital, University of Health Sciences, Ankara, Turkey

    Mehmet Ali Karagöz

  8. Division of Experimental Oncology/Unit of Urology, Urological Research Institute, IRCCS Ospedale San Raffaele, Milan, Italy

    Luca Villa

  9. Department of Urology, Biruni University School of Medicine, Istanbul, Turkey

    Kemal Sarıca

Authors
  1. Mehmet İlker Gökce
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  2. Selçuk Güven
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  3. Kremena Petkova
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  4. Tzevat Tefik
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  5. Muhammed Arif İbiş
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  6. Giray Sönmez
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  7. Nariman Gadzhiev
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  8. Murat Can Kiremit
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  9. Mehmet Ali Karagöz
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  10. Luca Villa
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  11. Kemal Sarıca
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Contributions

MIG: protocol/project development, manuscript writing/editing, SG: manuscript writing/editing, KP: data collection or management, TT: data analysis, data collection or management, MAI: data collection or management, manuscript writing/editing, GS: data analysis, data collection or management, NG: data collection or management, MCK: protocol/project development, data collection or management, MAK: data collection or management, LV: data collection or management, KS: protocol/project development, data analysis, manuscript writing/editing.

Corresponding author

Correspondence to Mehmet İlker Gökce.

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No conflict of interest was declared by the authors.

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For all participants, we received written informed consent.

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Gökce, M.İ., Güven, S., Petkova, K. et al. Patient compliance for metabolic evaluation and medical treatment (CoMET) in calcium-oxalate stone patients: prospective study by EULIS eCORE study group. World J Urol 41, 3135–3140 (2023). https://doi.org/10.1007/s00345-023-04610-w

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  • DOI: https://doi.org/10.1007/s00345-023-04610-w

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