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Outcomes of thulium prostatectomy with “Oyster technique” versus transurethral prostatectomy (TURP): a randomized control trial

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Abstract

Purpose

To compare the perioperative and postoperative outcomes between Oyster prostate vaporesection using Tm−YAG laser and the conventional transurethral prostatectomy using monopolar energy.

Methods

Patients with LUTS with an accumulative size of at least 60 ml were randomly assigned to one of two parallel groups to undergo Tm-YAG laser vaporesection (Group 1) or conventional monopolar transurethral prostatectomy (Group 2). The primary endpoints were the reduction in IPSS and the increase in Qmax postoperatively. Secondary endpoints included the Hemoglobin drop, the complication rate, the changes in urodynamic parameters, the duration of hospitalization and catheterization and the changes in IIEF during the 24-month follow-up.

Results

In total 32 and 30 patients were enrolled in Groups 1 and 2, respectively. Patient age (p = 0.422) and prostate volume were similar among the groups (p = 0.51). The outcomes in terms of IPSS decrease and Qmax amelioration were comparable (p = 0.449 and p = 0.237, respectively). Operative and hospitalization times were lower in Group 1 (p = 0.002 and p = 0.004, respectively). Hemoglobin drop, changes in urodynamic parameters and improvement in IIEF and QoL scores did not differ among the two Groups. The average time with the catheter was 2.06 ± 0.35 and 2.5 ± 0.82 (p = 0.003) days for Group 1 and Group 2, respectively. The overall complication rate was 6.2% for Group 1 and 13.3% for Group 2.

Conclusions

The Oyster technique leads to similar postoperative outcomes compared to the standard monopolar transurethral prostatectomy. The shorter catheterization, hospitalization and operation time should be considered advantages of the Oyster technique.

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Data availability

The data that support the findings of this study are available from the corresponding author, upon reasonable request.

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Authors and Affiliations

  1. Department of Urology, University Hospital of Patras, Patras, Greece

    Dimitrios Kotsiris, Vasileios Tatanis, Angelis Peteinaris, Konstantinos Pagonis, Panteleimon Ntasiotis, Constantinos Adamou, Evangelos Liatsikos & Panagiotis Kallidonis

  2. Department of Urology, Naval and Veterans Hospital, Chania, Greece

    Dimitrios Kotsiris

  3. 251 Hellenic Airforce Hospital, Athens, Greece

    Vasileios Tzenetidis

  4. Department of Anesthesiology and ICU, University Hospital of Patras, Patras, Greece

    Theofanis Vrettos

  5. Medical University of Vienna, Vienna, Austria

    Evangelos Liatsikos

Authors
  1. Dimitrios Kotsiris
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  2. Vasileios Tatanis
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  3. Angelis Peteinaris
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  4. Vasileios Tzenetidis
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  5. Konstantinos Pagonis
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  6. Panteleimon Ntasiotis
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  7. Constantinos Adamou
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  8. Theofanis Vrettos
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  9. Evangelos Liatsikos
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  10. Panagiotis Kallidonis
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Contributions

DK—Data collection and data analysis, interpretation of data and manuscript drafting. VT—Data analysis, interpretation of data and manuscript drafting. AP—Data collection and data analysis. VT—Data analysis, interpretation of data. KP—Data collection and data analysis. PN—Data collection and data analysis. CA—Data analysis, interpretation of data. TV—Critical revision. EL—Project development and critical revision. PK—Project development and conception, critical revision.

Corresponding author

Correspondence to Evangelos Liatsikos.

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Ethical approval

The study involves Humans Participants and has been carried out in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. Informed consent was obtained from all study participants.

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Kotsiris, D., Tatanis, V., Peteinaris, A. et al. Outcomes of thulium prostatectomy with “Oyster technique” versus transurethral prostatectomy (TURP): a randomized control trial. World J Urol 41, 2473–2479 (2023). https://doi.org/10.1007/s00345-023-04510-z

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  • DOI: https://doi.org/10.1007/s00345-023-04510-z

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