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An overlooked complication of the clean intermittent catheters: prostate calculi

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Although the clinical importance of prostate calculi has been understood over time, it is a urinary system disease that can cause different symptoms and can be ignored by urologists sometime. Clean intermittent catheter (CIC) is the gold standard method for bladder rehabilitation and urinary drainage in patients with neurogenic bladder. The aim of this study was to compare the incidence of prostate calculi and related pathologies between patients using CIC and not using CIC.


A total of 314 neurogenic bladder patients who were followed up and treated in our urology clinic were included in this study. The patients were divided into two groups as patients non-using CIC (Group-1, n:154) and patients using CIC (Group-2, n:160).Presence of prostate calculi, the number of CIC used per/day, plasma uric acid levels, urine parameters, mean-stone-density (MSD) and calculi sizes were retrospectively scanned from patient records.


In this study, no significant difference was observed between the parameters such as age, uric acid level, MSD, urine parameters, and other electrolyte levels (Table 1) While the incidence of prostate calculi in Group 1 was 23.4%; The incidence of prostate calculi in group 2 was 37.5(p = 0.007) (Fig. 2).


In this study, it was tried to show the relationship between the use of CIC and prostate calculi that cause LUTS and dysuria, which are generally ignored in clinical evaluation but do not pass in patients. As a result of this study, it was determined that the incidence of prostate calculi increased in patients using CIC.

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Fig. 1
Fig. 2

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Authors and Affiliations



GE: Project Development, Manuscript Writing, Data Managing, Retrospective scan. AA: Project Development, Data Analysis, Manuscript Editing, Editing of pictures and tables. MGS: Data Analysis, Manuscript Editing. MTK: Retrospective scan, Data Analysis. SG: Data Analysis, Manuscript Editing. MB: Project Development, Manuscript Editing.

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Correspondence to Gökhan Ecer.

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Authors declared that the research was conducted according to the principles of the World Medical Association Declaration of Helsinki “Ethical Principles for Medical Research Involving Human Subjects”. The study was performed in the Clinical Ethic Committee of Necmettin Erbakan University Meram Medicine Faculty (No: 2022/3865).

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Ecer, G., Aydin, A., Sönmez, M.G. et al. An overlooked complication of the clean intermittent catheters: prostate calculi. World J Urol 41, 1635–1640 (2023).

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