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Incidence and safety outcomes associated with active stone removal procedures (ASRP): a comparison between neurological and non-neurological patients using the French National Health Data Base

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Abstract

Purpose

To compare the incidence and the safety outcomes associated with active stone removal procedure (ASRP) between neurological and non-neurological patients.

Materials and methods

The present study was conducted using the data issued from the French National Health Data Base. All patients that have been hospitalized to undergo an ASRP between January 1 2012 and December 31 2018 were included and allocated to four neurological groups (multiple sclerosis, spinal dysraphism, paraplegia, tetraplegia) and one non-neurological group. The primary outcome was the rate of patients hospitalized at least once to undergo an ASRP over the study period. The secondary outcomes included the type of ASRP performed, the length of hospital stay, the rates of post-operative UTI, of early re-admission and re-treatments. Multivariate logistic regression was used to estimate odd ratios, the four neurological groups being compared to the non-neurological group.

Results

During the study period, 45,745,055 patients were hospitalised, with 151,850 of them presenting with an underlying neurological disease. Among the non-neurological patients, 0.89% underwent an ASRP, while 1.39% neurological patients did. Neurological patients presented with a lower rate of ESWL associated with a higher rate of PCNL, while the length of hospital stay, the rate of post-operative UTI, of early re-admission and of re-treatment were systematically increased (p < 0.001), when compared to non-neurological patients, regardless of the type of ASRP considered.

Conclusions

The results presented here confirm and clarify the incidence and the safety outcomes associated with ASRP within the neurological population and advocate for the emergence of a dedicated research field focusing on neuro-urolithiasis.

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Abbreviations

ASRP:

Active stone removal procedure

CCAM:

Classification Commune des Actes Médicaux

EWSL:

Extracorporeal shock wave lithotripsy

fURS:

Flexible ureteroscopy

ICD 10:

International Classification of Disease 10

MS:

Multiple sclerosis

PCNL:

Per cutaneous nephrolithotomy

PMSI:

Programme de Médicalisation des Systèmes d’Information

rURS:

Rigid ureteroscopy

SCI:

Spinal cord injury

SD:

Spinal dysraphism

UTI:

Urinary tract infection

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Funding

The authors did not receive support from any organization for the submitted work. All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript.

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Authors and Affiliations

  1. Department of Urology, Claude Huriez Hospital, CHU Lille, Univ Lille, Lille University Hospital, 1 rue Polonovski, 59000, Lille Cedex, France

    Florian Beraud & Xavier Biardeau

  2. Medical Information Department, CHU Lille, Univ Lille, Lille University Hospital, 1 rue Polonovski, 59000, Lille Cedex, France

    Guillaume Clément & Xavier Lenne

Authors
  1. Florian Beraud
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  2. Guillaume Clément
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  3. Xavier Lenne
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  4. Xavier Biardeau
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Contributions

FB: project development, manuscript writing and editing. GC: data collection. XL: statistical analysis. XB: project development, manuscript editing, supervision.

Corresponding author

Correspondence to Florian Beraud.

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Conflict of interest

I hereby, Florian BERAUD, MD, declare that I have the full approval of my esteemed colleagues, and that I do not have any competing interests. This work is an original article that is not submitted, nor published elsewhere.

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We did not make any research involving human participants nor animals.

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No informed consent was required, we only used anonymized administrative retrospective data.

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Beraud, F., Clément, G., Lenne, X. et al. Incidence and safety outcomes associated with active stone removal procedures (ASRP): a comparison between neurological and non-neurological patients using the French National Health Data Base. World J Urol 40, 1821–1827 (2022). https://doi.org/10.1007/s00345-022-04054-8

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  • DOI: https://doi.org/10.1007/s00345-022-04054-8

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