Purpose and objective
To evaluate and compare the incidences of post-operative pelvic pain (PPP) in patients undergoing ablation, enucleation and conventional transurethral resection of the prostate (TURP).
A systematic review and meta-analysis was conducted according to the PRISMA guidelines. Using MEDLINE via PubMed and Cochrane CENTRAL, randomised control trials (RCTs) and observational studies reporting PPP rates post-ablation, enucleation or TURP were identified. The risk of biases (RoB) in RCTs and observation studies were assessed using the Cochrane RoB1.0 tool and the Newcastle–Ottawa Scale, respectively.
62 studies were included for qualitative analysis, while 51 of them reported number of patients with PPP post-intervention. Three observational studies and 13 RCTs compared the rates of PPP in patients undergoing ablation, enucleation or TURP. The most reported types of PPP are dysuria, abdominal pain and irritative symptoms. The pooled incidence of PPP at 1-month follow-up in patients undergoing ablation, enucleation and TURP were 0.15 (95% CI 0.10–0.22), 0.09 (95% CI 0.04–0.19 and 0.10 (95% CI 0.06–0.15), respectively. PPP is no longer prevalent at 3-months and onwards post-operatively. Ablation is associated with a higher risk of PPP than enucleation (RR 2.19, 95% CI 1.04–4.62) and TURP (RR 2.40, 95% CI 1.03–5.62) in observational studies but not RCTs; and there were no significant differences in the rates of PPP upon comparison of other modalities.
PPP is common after transurethral benign prostatic hyperplasia surgery. Patients undergoing ablation had a higher rate of post-intervention PPP than those undergoing enucleation and TURP in observational studies.
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Lepor H (2004) Pathophysiology, epidemiology, and natural history of benign prostatic hyperplasia. Rev Urol 6(Suppl 9):S3–S10
Bachmann A, Schürch L, Ruszat R, Wyler SF, Seifert HH, Müller A et al (2005) Photoselective vaporization (PVP) versus transurethral resection of the prostate (TURP): a prospective bi-centre study of perioperative morbidity and early functional outcome. Eur Urol 48(6):965–71 (discussion 72)
Ahyai SA, Gilling P, Kaplan SA, Kuntz RM, Madersbacher S, Montorsi F et al (2010) Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement. Eur Urol 58(3):384–397
Karaköse A, Prof A (2020) Clinical comparison of two minimal invasive techniques in the treatment of benign prostatic enlargement over 90 ml: BIVap (Richard WOLF®) saline vaporization of the prostate vs. Bipolar plasmakinetic TURP. Arch Esp Urol 73:140–6
Wroclawski ML, Carneiro A, Amarante RD, Oliveira CE, Shimanoe V, Bianco BA et al (2016) ‘Button type’ bipolar plasma vaporisation of the prostate compared with standard transurethral resection: a systematic review and meta-analysis of short-term outcome studies. BJU Int 117(4):662–668
Schatzl G, Madersbacher S, Lang T, Marberger M (1997) The early postoperative morbidity of transurethral resection of the prostate and of 4 minimally invasive treatment alternatives. J Urol 158(1):105–10 (discussion10-1)
Jones P, Alzweri L, Rai BP, Somani BK, Bates C, Aboumarzouk OM (2016) Holmium laser enucleation versus simple prostatectomy for treating large prostates: results of a systematic review and meta-analysis. Arab J Urol 14(1):50–58
Covidence systematic review software Melbourne, Australia: Veritas Health Innovation; Available from: www.covidence.org.
McGuinness LA, Higgins JPT (2020) Risk-of-bias VISualization (robvis): an R package and Shiny web app for visualizing risk-of-bias assessments. Res Synth Methods 12(1):55–61
Al-Ansari A, Younes N, Sampige VP, Al-Rumaihi K, Ghafouri A, Gul T et al (2010) GreenLight HPS 120-W laser vaporization versus transurethral resection of the prostate for treatment of benign prostatic hyperplasia: a randomized clinical trial with midterm follow-up. Eur Urol 58(3):349–355
Zhu Z, Shen Z, Tu F, Zhu Y, Sun F, Shao Y et al (2012) Thulium laser vaporesection versus transurethral electrovaporization of the prostate in high-risk patients with benign prostatic hyperplasia. Photomed Laser Surg 30(12):714–718
Rieken M, Bonkat G, Müller G, Wyler S, Mundorff NE, Püschel H et al (2013) The effect of increased maximum power output on perioperative and early postoperative outcome in photoselective vaporization of the prostate. Lasers Surg Med 45(1):28–33
Gupta NP, Singh A, Kumar R (2007) Transurethral vapor resection of prostate is a good alternative for prostates >70 g. J Endourol 21(12):1543–1546
Karakose A (2020) Clinical comparison of two minimal invasive techniques in the treatment of benign prostatic enlargement over 90 ml: BIVAP (Richard Wolf®) saline vaporization of the prostate vs bipolar plasmakinetic TURP. Arch Esp Urol. 73(2):140–6
Mottet N, Anidjar M, Bourdon O, Louis JF, Teillac P, Costa P et al (1999) Randomized comparison of transurethral electroresection and holmium: YAG laser vaporization for symptomatic benign prostatic hyperplasia. J Endourol 13(2):127–130
Erol A, Keskin SK, Başok EK, Dönmezer S (2018) Diode 980 nm laser vaporesection of the prostate: a comparison of 150 to 250 Watt. J Urol Surg 5(2):83–87
Gilling PJ, Cass CB, Malcolm A, Cresswell M, Fraundorfer MR, Kabalin JN (1998) Holmium laser resection of the prostate versus neodymium: yttrium-aluminum-garnet visual laser ablation of the prostate: a randomized prospective comparison of two techniques for laser prostatectomy. Urology 51(4):573–577
Sood R, Manasa T, Goel H, Singh RK, Singh R, Khattar N et al (2017) Day care bipolar transurethral resection vs photoselective vaporisation under sedoanalgesia: a prospective, randomised study of the management of benign prostatic hyperplasia. Arab J Urol 15(4):331–338
Mithani MH, Khalid SE, Khan SA, Sharif I, Awan AS, Mithani S et al (2018) Outcome of 980 nm diode laser vaporization for benign prostatic hyperplasia: a prospective study. Investig Clin Urol 59(6):392–398
Yip SK, Chan NH, Chiu P, Lee KW, Ng CF (2011) A randomized controlled trial comparing the efficacy of hybrid bipolar transurethral vaporization and resection of the prostate with bipolar transurethral resection of the prostate. J Endourol 25(12):1889–1894
Te AE, Malloy TR, Stein BS, Ulchaker JC, Nseyo UO, Hai MA et al (2004) Photoselective vaporization of the prostate for the treatment of benign prostatic hyperplasia: 12-month results from the first United States multicenter prospective trial. J Urol 172(4 Pt 1):1404–1408
Pillai RG, Al Naieb Z, Angamuthu S, Mundackal T (2014) Diode laser vaporisation of the prostate vs diode laser under cold irrigation: a randomised control trial. Arab J Urol 12(4):245–50
Botto H, Lebret T, Barré P, Orsoni JL, Hervé JM, Lugagne PM (2001) Electrovaporization of the prostate with the Gyrus device. J Endourol 15(3):313–316
Reich O, Schlenker B, Gratzke C, Tilki D, Riecken M, Stief C et al (2010) Plasma vaporisation of the prostate: initial clinical results. Eur Urol 57(4):693–697
Bepple JL, Barone BB, Eure G (2009) The effect of dutasteride on the efficacy of photoselective vaporization of the prostate: results of a randomized, placebo-controlled, double-blind study (DOP trial). Urology 74(5):1101–1104
Kim KS, Lee SH, Cho HJ, Suh HJ, Lee DH, Choi YS (2019) Comparison of bipolar plasma vaporization versus standard Holmium laser enucleation of the prostate: surgical procedures and clinical outcomes for small prostate volumes. J Clin Med. 8(7):1007
Heinrich E, Schiefelbein F, Schoen G (2007) Technique and short-term outcome of green light laser (KTP, 80W) vaporisation of the prostate. Eur Urol 52(6):1632–1637
Ruszat R, Seitz M, Wyler SF, Müller G, Rieken M, Bonkat G et al (2009) Prospective single-centre comparison of 120-W diode-pumped solid-state high-intensity system laser vaporization of the prostate and 200-W high-intensive diode-laser ablation of the prostate for treating benign prostatic hyperplasia. BJU Int 104(6):820–825
Gupta NP, Doddamani D, Aron M, Hemal AK (2002) Vapor resection: a good alternative to standard loop resection in the management of prostates >40 cc. J Endourol 16(10):767–771
van Melick HH, van Venrooij GE, Eckhardt MD, Boon TA (2003) A randomized controlled trial comparing transurethral resection of the prostate, contact laser prostatectomy and electrovaporization in men with benign prostatic hyperplasia: analysis of subjective changes, morbidity and mortality. J Urol 169(4):1411–1416
Malek RS, Kuntzman RS, Barrett DM (2000) High power potassium-titanyl-phosphate laser vaporization prostatectomy. J Urol 163(6):1730–1733
Malek RS, Kuntzman RS, Barrett DM (2005) Photoselective potassium-titanyl-phosphate laser vaporization of the benign obstructive prostate: observations on long-term outcomes. J Urol 174(4 Pt 1):1344–1348
Volkan T, Ihsan TA, Yilmaz O, Emin O, Selcuk S, Koray K et al (2005) Short term outcomes of high power (80 W) potassium-titanyl-phosphate laser vaporization of the prostate. Eur Urol 48(4):608–613
Tugcu V, Tasci AI, Sahin S, Ordekci Y, Karakas OF, Zorluoglu F (2007) Outcomes of 80 W KTP laser vaporization of the large prostate. Urol Int 79(4):316–320
Hai MA, Malek RS (2003) Photoselective vaporization of the prostate: initial experience with a new 80 W KTP laser for the treatment of benign prostatic hyperplasia. J Endourol 17(2):93–96
Chiang PH, Chen CH, Kang CH, Chuang YC (2010) GreenLight HPS laser 120-W versus diode laser 200-W vaporization of the prostate: comparative clinical experience. Lasers Surg Med 42(7):624–629
Aydogdu O, Karakose A, Atesci YZ (2014) A clinical study comparing BIVAP saline vaporization of the prostate with bipolar TURP in patients with prostate volume 30 to 80 mL: early complications, physiological changes and postoperative follow-up outcomes. Can Urol Assoc J 8(7–8):E485–E489
Hori Y, Kuromatsu I, Sugimura Y (2008) Photoselective vaporization of the prostate using high power (80 W) KTP laser: one year follow up of the first 101 patients in Japan. Int J Urol 15(12):1067–1071
Tao W, Xue B, Sun C, Yang D, Zhang Y, Shan Y (2019) Comparison of vaporization using 120-W GreenLight laser versus 2-micrometer continuous laser for treating benign prostatic hyperplasia: a 24-month follow-up study of a single center. J Xray Sci Technol 27(4):755–764
Mu XN, Wang SJ, Chen J, Jin XB, Huang ZX, Zhang LY (2016) Bipolar transurethral enucleation of prostate versus photoselective vaporization for symptomatic benign prostatic hyperplasia (>70 ml). Asian journal of andrology. 18(no pagination).
Carter A, Sells H, Speakman M, Ewings P, O’Boyle P, MacDonagh R (1999) Quality of life changes following KTP/Nd:YAG laser treatment of the prostate and TURP. Eur Urol 36(2):92–98
Kollmorgen TA, Malek RS, Barrett DM (1996) Laser prostatectomy: two and a half year’s experience with aggressive multifocal therapy. Urology 48(2):217–222
Liu Z, Li YW, Wu WR, Lu Q (2017) Long-term clinical efficacy and safety profile of transurethral resection of prostate versus plasmakinetic resection of the prostate for benign prostatic hyperplasia. Urology 103:198–203
Kumar N, Vasudeva P, Kumar A, Singh H (2018) Prospective randomized comparison of monopolar TURP, bipolar TURP and photoselective vaporization of the prostate in patients with benign prostatic obstruction: 36 months outcome. Low Urin Tract Symptoms 10(1):17–20
Kranzbühler B, Wettstein MS, Fankhauser CD, Grossmann NC, Gross O, Poyet C et al (2013) Pure bipolar plasma vaporization of the prostate: the Zürich experience. J Endourol 27(10):1261–1266
Anson K, Nawrocki J, Buckley J, Fowler C, Kirby R, Lawrence W et al (1995) A multicenter, randomized, prospective study of endoscopic laser ablation versus transurethral resection of the prostate. Urology 46(3):305–310
Fu WJ, Hong BF, Yang Y, Cai W, Gao JP, Wang CY et al (2005) Photoselective vaporization of the prostate in the treatment of benign prostatic hyperplasia. Chin Med J (Engl) 118(19):1610–1614
Rigatti L, Naspro R, Salonia A, Centemero A, Ghezzi M, Guazzoni G et al (2006) Urodynamics after TURP and HoLEP in urodynamically obstructed patients: are there any differences at 1 year of follow-up? Urology 67(6):1193–1198
Sinha RJ, Singh V, Bhaskar V, Purkait B, Jhanwar A (2017) Outcomes of transurethral resection and holmium laser enucleation in more than 60 g of prostate: a prospective randomized study. Indian journal of urology. 33.
Kim SH, Oh SJ (2014) Nonspecific genitourinary pain improves after prostatectomy using holmium laser enucleation of prostate in patients with benign prostatic hyperplasia: a prospective study. PLoS One 9(6):e98979
Bajic P, Noriega N, Gorbonos A, Karpman E (2019) GreenLight Laser Enucleation of the Prostate (GreenLEP): initial experience with a simplified technique. Urology 131:250–254
Elshal AM, Elkoushy MA, El-Nahas AR, Shoma AM, Nabeeh A, Carrier S et al (2015) GreenLightTM laser (XPS) photoselective vapo-enucleation versus holmium laser enucleation of the prostate for the treatment of symptomatic benign prostatic hyperplasia: a randomized controlled study. J Urol 193(3):927–34
Gilling P, Barber N, Bidair M, Anderson P, Sutton M, Aho T et al (2018) WATER: a double-blind, randomized, controlled trial of aquablation® vs transurethral resection of the prostate in benign prostatic hyperplasia. J Urol 199(5):1252–1261
Singh H, Desai MR, Shrivastav P, Vani K (2005) Bipolar versus monopolar transurethral resection of prostate: randomized controlled study. J Endourol 19(3):333–338
Tascı AI, Ilbey YO, Tugcu V, Cicekler O, Cevik C, Zoroglu F (2011) Transurethral resection of the prostate with monopolar resectoscope: single-surgeon experience and long-term results of after 3589 procedures. Urology 78(5):1151–1155
Quek KF, Loh CS, Low WY, Razack AH (2001) Quality of life assessment before and after transurethral resection of the prostate in patients with lower urinary tract symptoms. World J Urol 19(5):358–364
MacDonagh RP, Cliff AM, Speakman MJ, O’Boyle PJ, Ewings P, Gudex C (1997) The use of generic measures of health-related quality of life in the assessment of outcome from transurethral resection of the prostate. Br J Urol 79(3):401–408
Li K, Wang D, Hu C, Mao Y, Li M, Si-Tu J et al (2018) A novel Modification of transurethral enucleation and resection of the prostate in patients with prostate glands larger than 80 mL: surgical procedures and clinical outcomes. Urology 113:153–159
Gravas SJNC, Cornu JN, Gacci M, Gratzke C, Herrmann TRW, Mamoulakis C et al (2020) Management of non-neurogenic male LUTS. EAU Guidelines. Edn. presented at the EAU Annual Congress Amsterdam. ISBN 978-94-92671-07-3.
Herrmann TRW, Gravas S, de la Rosette JJ, Wolters M, Anastasiadis AG, Giannakis I (2020) Lasers in transurethral enucleation of the prostate-do we really need them. J Clin Med. 9(5):1412
Cornu JN, Ahyai S, Bachmann A, de la Rosette J, Gilling P, Gratzke C et al (2015) A systematic review and meta-analysis of functional outcomes and complications following Transurethral procedures for lower urinary tract symptoms resulting from Benign Prostatic obstruction: an update. Eur Urol 67(6):1066–1096
Wroclawski ML, Teles SB, Amaral BS, Kayano PP, Cha JD, Carneiro A et al (2020) A systematic review and meta-analysis of the safety and efficacy of endoscopic enucleation and non-enucleation procedures for benign prostatic enlargement. World J Urol 38(7):1663–1684
Wroclawski ML, Teles SB, Carneiro A (2020) Anatomical endoscopic enucleation of the prostate: the next gold standard? No! (or not yet!). Andrologia. 52(8):e13707
Kim SJ, Al Hussein Alawamlh O, Chughtai B, Lee RK (2018) Lower urinary tract symptoms following transurethral resection of prostate. Curr Urol Rep 19(10):85
Agarwal A, Eryuzlu LN, Cartwright R, Thorlund K, Tammela TL, Guyatt GH et al (2014) What is the most bothersome lower urinary tract symptom? Individual- and population-level perspectives for both men and women. Eur Urol 65(6):1211–1217
Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2003) The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Urology 61(1):37–49
Elbadawi A, Yalla SV, Resnick NM (1993) Structural basis of geriatric voiding dysfunction. IV. bladder outlet obstruction. J Urol 150(5 Part 2):1681–95
Su S, Lin J, Liang L, Liu L, Chen Z, Gao Y (2020) The efficacy and safety of mirabegron on overactive bladder induced by benign prostatic hyperplasia in men receiving tamsulosin therapy: a systematic review and meta-analysis. Medicine (United States). 99(4):e18802
Shin YS, Zhang LT, Zhao C, Kim YG, Park JK (2014) Twelve-week, prospective, open-label, randomized trial on the effects of an anticholinergic agent or antidiuretic agent as add-on therapy to an alpha-blocker for lower urinary tract symptoms. Clin Interv Aging 9:1021–1030
Sakalis V, Sfiggas V, Vouros I, Salpiggidis G, Papathanasiou A, Apostolidis A (2018) Combination of solifenacin with tamsulosin reduces prostate volume and vascularity as opposed to tamsulosin monotherapy in patients with benign prostate enlargement and overactive bladder symptoms: results from a randomized pilot study. Int J Urol 25(8):737–745
Sakalis V, Sfiggas V, Vouros I, Salpiggidis G, Papathanasiou A, Apostolidis A (2015) Is there an effect of antimuscarinics on the prostate? Preliminary results from a randomized study in patients with benign prostate enlargement (BPE) and overactive bladder (OAB). Eur Urol Suppl 14(2):e686
Park KK, Lee SH, Chung BH, Kim SJ, Kwak C, Son HC et al (2013) Efficacy and safety of low-dose anticholinergics to treat men with lower urinary tract symptoms with overactive bladder: a retrospective study based on real life practice. Prostate Int 1(1):37–41
Lee YS, Lee KS, Park WH, Kim JC, Hong S, Chung BH et al (2012) Persistence of solifenacin combination treatment in men with overactive bladder symptoms after tamsulosin monotherapy. Eur Urol Suppl 11(1):e688
Lee YS, Lee KS, Kim JC, Hong S, Chung BH, Kim CS et al (2014) Persistence with solifenacin add-on therapy in men with benign prostate obstruction and residual symptoms of overactive bladder after tamsulosin monotherapy. Int J Clin Pract 68(12):1496–1502
Lee S, Shin Y, Kim J, Zhang L, Zhao C, Kim Y et al (2014) Twelve-week, prospective, open label, randomized trial for the effect of anticholinergic agent or antidiuretic agent as add-on therapy to alpha-blocker for lower urinary tract symptoms. Urology 84(4):S226
Lee KW, Hur KJ, Kim SH, Cho SY, Bae SR, Park BH et al (2017) Initial use of high-dose anticholinergics combined with alpha-blockers for male lower urinary tract symptoms with overactive bladder: a prospective, randomized preliminary study. Low Urin Tract Symptoms 9(3):129–33
Castellani D, Pirola GM, Pacchetti A, Saredi G, Dellabella M (2020) State of the art of thulium laser enucleation and vapoenucleation of the prostate: a systematic review. Urology 136:19–34
Lee HN, Lee Y, Han J, Ju SH, Lee KS, Hong S et al (2010) Rate and predictive factors of the anticholinergic add-on therapy in men with residual overactive bladder symptom after 4 weeks of (-blocker monotherapy. Int Urogynecol J Pelvic Floor Dysfunct 21:S118–S120
Kwon SY, Lee KS, Kim KH, Seo YJ, Kang YJ (2019) Efficacy of mirabegron addition in benign prostatic hyperplasia with persistent overactive symptoms: a prospective study. Int J Urol 26(Supplement 2):119–120
Kara C, Resorlu B, Cicekbilek I, Unsal A (2010) Analgesic efficacy and safety of nonsteroidal anti-inflammatory drugs after transurethral resection of prostate. Int Braz J Urol 36(1):49–54
Welliver C, Helo S, McVary KT (2017) Technique considerations and complication management in transurethral resection of the prostate and photoselective vaporization of the prostate. Transl Androl Urol 6(4):695–703
Bates STM (2000) Short course oral prednisolone therapy in chronic abacterial prostatitis and prostatodynia: case reports of three responders and one non-responder. Sex Transm Inf 76:398–400
Jh J (2012) Effects of a short course of oral prednisolone in patients with bladder pain syndrome with fluctuating, worsening pain despite low-dose triple therapy. Int Neurourol J 16(4):175–180
Woods E (2010) Laser ablation of the prostate: a safe effective treatment of obstructive benign prostatic disease. Can Urol Assoc J 4(5):344–346
Sun EC, Darnall BD, Baker LC, Mackey S (2016) Incidence of and risk factors for chronic opioid use among opioid-naive patients in the postoperative period. JAMA Intern Med 176(9):1286–1293
Agarwal A, Dhiraaj S, Pawar S, Kapoor R, Gupta D, Singh PK (2007) An evaluation of the efficacy of gabapentin for prevention of catheter-related bladder discomfort: a prospective, randomized, placebo-controlled Double-Blind Study. Anesth Analg 105(5):1454–1457
Tehranchi A, Rezaei Y, Shojaee R (2014) Tolterodine to relieve urinary symptoms following transurethral resection of the prostate: a double-blind placebo-controlled randomized clinical trial. Korean J Urol 55(4):260–264
Lee KS, Kakizaki H, Yamamoto O, Jong JJ, Katou D, Sumarsono B et al (2019) Efficacy and safety of add-on mirabegron vs placebo to tamsulosin in men with overactive bladder symptoms (match study). Int J Urol 26(Supplement 2):65
Lee JY, Kim HW, Lee SJ, Koh JS, Suh HJ, Chancellor MB (2004) Comparison of doxazosin with or without tolterodine in men with symptomatic bladder outlet obstruction and an overactive bladder. BJU Int 94(6):817–820
Marszalek M, Berger I, Madersbacher S (2009) Low-energy extracorporeal shock wave therapy for chronic pelvic pain syndrome: finally, the magic bullet? Eur Urol 56(3):425–426
Zimmermann R, Cumpanas A, Miclea F, Janetschek G (2009) Extracorporeal shock wave therapy for the treatment of chronic pelvic pain syndrome in males: a randomised, double-blind, placebo-controlled study. Eur Urol 56(3):418–424
Brunahl CA, Klotz SGR, Dybowski C, Riegel B, Gregorzik S, Tripp DA et al (2018) Combined cognitive-behavioural and physiotherapeutic therapy for patients with chronic pelvic pain syndrome (COMBI-CPPS): study protocol for a controlled feasibility trial. Trials 19(1):20
Berry A, Barratt A (2002) Prophylactic antibiotic use in transurethral prostatic resection: a meta-analysis. J Urol 167(2 Pt 1):571–577
Qiang W, Jianchen W, MacDonald R, Monga M, Wilt TJ (2005) Antibiotic prophylaxis for transurethral prostatic resection in men with preoperative urine containing less than 1,00,000 bacteria per ml: a systematic review. J Urol 173(4):1175–1181
Thomas JA, Tubaro A, Barber N, d’Ancona F, Muir G, Witzsch U et al (2016) A multicenter randomized noninferiority trial comparing GreenLight-XPS laser vaporization of the prostate and transurethral resection of the prostate for the treatment of Benign Prostatic Obstruction: Two-year outcomes of the GOLIATH Study. Eur Urol 69(1):94–102
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Wroclawski, M.L., Castellani, D., Heldwein, F.L. et al. Shedding light on polypragmasy of pain after transurethral prostate surgery procedures: a systematic review and meta-analysis. World J Urol (2021). https://doi.org/10.1007/s00345-021-03678-6
- Prostatic hyperplasia
- Urological surgical procedures
- Transurethral resection of prostate